PDB: 53 resultsInfo pagesStatus searchChemie searchBIRD

---

3H73	Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with DANA Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase A Authors: Hsiao, Y.-S, Tong, L. Deposit date: 2009-04-24 Release date: 2009-05-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun., 380, 2009
2W20	Structure of the catalytic domain of the native NanA sialidase from Streptococcus pneumoniae Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... Authors: Xu, G, Andrew, P.W, Taylor, G.L. Deposit date: 2008-10-21 Release date: 2008-12-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Structure of the Catalytic Domain of Streptococcus Pneumoniae Sialidase Nana. Acta Crystallogr.,Sect.F, 64, 2008
3H72	Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with NANA Descriptor: N-acetyl-alpha-neuraminic acid, Sialidase A Authors: Hsiao, Y.-S, Tong, L. Deposit date: 2009-04-24 Release date: 2009-05-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun., 380, 2009
3H71	Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) Descriptor: Sialidase A Authors: Hsiao, Y.-S, Tong, L. Deposit date: 2009-04-24 Release date: 2009-05-12 Last modified: 2019-09-04 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun., 380, 2009
5F9T	Crystal Structure of Streptococcus pneumoniae NanC, covalent complex with a fluorinated Neu5Ac derivative Descriptor: (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, GLYCEROL, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-12-10 Release date: 2015-12-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
2JKB	Crystal structure of Streptococcus pneumoniae NanB in complex with 2, 7-anhydro-Neu5Ac Descriptor: 1,2-ETHANEDIOL, 2-ACETYLAMINO-7-(1,2-DIHYDROXY-ETHYL)-3-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCTANE-5-CARBOXYLIC ACID, SIALIDASE B Authors: Gut, H, King, S.J, Walsh, M.A. Deposit date: 2008-08-26 Release date: 2008-09-16 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Structural and Functional Studies of Streptococcus Pneumoniae Neuraminidase B: An Intramolecular Trans-Sialidase. FEBS Lett., 582, 2008
2VW0	Crystal structure of the NanB sialidase from Streptococcus pneumoniae Descriptor: GLYCEROL, SIALIDASE B Authors: Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. Deposit date: 2008-06-13 Release date: 2008-06-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae J.Mol.Biol., 384, 2008
2VW1	Crystal structure of the NanB sialidase from Streptococcus pneumoniae Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, SIALIDASE B Authors: Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. Deposit date: 2008-06-13 Release date: 2008-06-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae J.Mol.Biol., 384, 2008
2VW2	Crystal structure of the NanB sialidase from Streptococcus pneumoniae Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SIALIDASE B Authors: Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. Deposit date: 2008-06-13 Release date: 2008-06-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae J.Mol.Biol., 384, 2008
4XJ8	Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 5.0 in 50mM sodium Acetate with DMSO Descriptor: Sialidase B Authors: Brear, P. Deposit date: 2015-01-08 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.749 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XE9	Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2014-12-23 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.84 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XHB	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES Descriptor: (1R,2S)-cyclopentane-1,2-diol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sialidase B Authors: Brear, P. Deposit date: 2015-01-05 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.88 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... Authors: Brear, P. Deposit date: 2015-01-09 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.53 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4FPO	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-chloro-4-methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-chloro-4-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.591 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FP2	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2[(Cyclohexylmethyl)ammonio]sulfonate Descriptor: 2-[(cyclohexylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPL	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3,4-dichlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3,4-dichlorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPE	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.181 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPG	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Hydroxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-hydroxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.576 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-ammoniopropane-1-sulfonate Descriptor: 3-aminopropane-1-sulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FP3	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(Furan-2-ylmethyl)ammonio]sulfonate Descriptor: 2-[(furan-2-ylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.743 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPJ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-bromobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-23 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOQ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-aminoethanesulfonic acid Descriptor: 2-AMINOETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOV	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPC	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-chlorobenzyl)amino]ethanesulfonic acid, GLYCEROL, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012

 

123>