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4QN0
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Crystal structure of the CPS-6 mutant Q130K
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Lin, J.L.J, Yuan, H.S.
Deposit date:2014-06-17
Release date:2015-06-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
Cell Rep, 16, 2016
1ZM8
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BU of 1zm8 by Molmil
Apo Crystal structure of Nuclease A from Anabaena sp.
Descriptor: MANGANESE (II) ION, Nuclease, SODIUM ION, ...
Authors:Ghosh, M, Meiss, G, Pingoud, A, London, R.E, Pedersen, L.C.
Deposit date:2005-05-10
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Mechanism of Nuclease A, a beta beta alpha Metal Nuclease from Anabaena.
J.Biol.Chem., 280, 2005
1G8T
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BU of 1g8t by Molmil
SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT 1.1 A RESOLUTION
Descriptor: MAGNESIUM ION, NUCLEASE SM2 ISOFORM, SULFATE ION
Authors:Lunin, V.V, Perbandt, M, Betzel, C.H, Mikhailov, A.M.
Deposit date:2000-11-21
Release date:2000-12-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism.
Acta Crystallogr.,Sect.D, 56, 2000
1QAE
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THE ACTIVE SITE OF SERRATIA ENDONUCLEASE CONTAINS A CONSERVED MAGNESIUM-WATER CLUSTER
Descriptor: MAGNESIUM ION, PROTEIN (EXTRACELLULAR ENDONUCLEASE)
Authors:Miller, M.D, Krause, K.L.
Deposit date:1999-03-03
Release date:1999-05-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The active site of Serratia endonuclease contains a conserved magnesium-water cluster.
J.Mol.Biol., 288, 1999
1QL0
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BU of 1ql0 by Molmil
Sm Endonuclease from Seratia marcenscens at atomic resolution
Descriptor: MAGNESIUM ION, NUCLEASE
Authors:Perbandt, M, Mikhailov, A.M, Betzel, C.H.
Deposit date:1999-08-18
Release date:2000-05-07
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic Structure of the Serratia Marcescens Endonuclease at 1.1 A Resolution and the Enzyme Reaction Mechanism.
Acta Crystallogr.,Sect.D, 56, 2000
4E3Y
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BU of 4e3y by Molmil
X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Lashkov, A.A, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M.
Deposit date:2012-03-11
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution
To be Published
1SMN
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IDENTIFICATION OF THE SERRATIA ENDONUCLEASE DIMER: STRUCTURAL BASIS AND IMPLICATIONS FOR CATALYSIS
Descriptor: EXTRACELLULAR ENDONUCLEASE
Authors:Miller, M.D, Krause, K.L.
Deposit date:1995-01-25
Release date:1996-01-29
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Identification of the Serratia endonuclease dimer: structural basis and implications for catalysis.
Protein Sci., 5, 1996
3S5B
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BU of 3s5b by Molmil
Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans
Descriptor: Endonuclease G, MAGNESIUM ION
Authors:Yuan, H.S, Lin, J.L.J.
Deposit date:2011-05-23
Release date:2012-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans
J.Biol.Chem., 287, 2012
5FGW
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BU of 5fgw by Molmil
Structure of Sda1 nuclease with bound zinc ion
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Moon, A.F, Krahn, J.M, Xun, L, Cuneo, M.J, Pedersen, L.C.
Deposit date:2015-12-21
Release date:2016-03-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.
Nucleic Acids Res., 44, 2016
6M3T
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BU of 6m3t by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P41212
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Park, K.H, Woo, E.J.
Deposit date:2020-03-04
Release date:2020-08-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6LYF
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BU of 6lyf by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/Se-Met)
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Park, K.H, Woo, E.J.
Deposit date:2020-02-14
Release date:2020-08-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6M3F
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BU of 6m3f by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Park, K.H, Woo, E.J.
Deposit date:2020-03-03
Release date:2020-08-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6M3U
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BU of 6m3u by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C100A), space group C2
Descriptor: Endonuclease G, mitochondrial
Authors:Park, K.H, Woo, E.J.
Deposit date:2020-03-04
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of the mouse endonuclease EndoG(H138A/C100A), space group C2
To Be Published
3OWV
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BU of 3owv by Molmil
Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae
Descriptor: CHLORIDE ION, DNA-entry nuclease, MAGNESIUM ION
Authors:Moon, A.F, Midon, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
Deposit date:2010-09-20
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
Nucleic Acids Res., 39, 2011
6NJT
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BU of 6njt by Molmil
Mouse endonuclease G mutant - H97A
Descriptor: CHLORIDE ION, Endonuclease G, mitochondrial, ...
Authors:Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S.
Deposit date:2019-01-04
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.
Nucleic Acids Res., 48, 2020
6NJU
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BU of 6nju by Molmil
Mouse endonuclease G mutant H97A bound to A-DNA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DNA (5'-D(CCGGCGCCGG)-3'), ...
Authors:Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S.
Deposit date:2019-01-04
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.
Nucleic Acids Res., 48, 2020
5GKP
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BU of 5gkp by Molmil
Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA
Descriptor: DNA (5'-D(*TP*TP*TP*TP*T)-3'), Endonuclease G, mitochondrial, ...
Authors:Lin, J.L, Yuan, H.S.
Deposit date:2016-07-05
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
5GKC
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BU of 5gkc by Molmil
The crystal structure of the CPS-6 H148A/F122A
Descriptor: Endonuclease G, mitochondrial
Authors:Lin, J.L, Yuan, H.S.
Deposit date:2016-07-04
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
8GHR
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BU of 8ghr by Molmil
Structure of human ENPP1 in complex with variable heavy domain VH27.2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Carozza, J.A, Wang, H, Solomon, P.E, Wells, J.A, Li, L.
Deposit date:2023-03-10
Release date:2023-08-02
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Discovery of VH domains that allosterically inhibit ENPP1.
Nat.Chem.Biol., 20, 2024
2O3B
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BU of 2o3b by Molmil
Crystal structure complex of Nuclease A (NucA) with intra-cellular inhibitor NuiA
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Ghosh, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
Deposit date:2006-12-01
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.
J.Biol.Chem., 282, 2007
6IID
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BU of 6iid by Molmil
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Descriptor: DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-10-04
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
3ISM
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BU of 3ism by Molmil
Crystal structure of the EndoG/EndoGI complex: Mechanism of EndoG inhibition
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CG4930, CG8862, ...
Authors:Loll, B, Gebhardt, M, Wahle, E, Meinhart, A.
Deposit date:2009-08-26
Release date:2009-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
Nucleic Acids Res., 37, 2009
7R6V
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BU of 7r6v by Molmil
Human EXOG complexed with dRP-containing DNA
Descriptor: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*AP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Szymanski, M.R, Yin, Y.W.
Deposit date:2021-06-23
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Human EXOG possesses strong AP hydrolysis activity
To Be Published
7R6T
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BU of 7r6t by Molmil
Human EXOG complexed with dRP-containing DNA
Descriptor: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*A)-3'), DNA (5'-D(3DR)P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), MAGNESIUM ION, ...
Authors:Szymanski, M.R, Yin, Y.W.
Deposit date:2021-06-23
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Human EXOG possesses strong AP hydrolysis activity
To Be Published
4A1N
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Human Mitochondrial endo-exonuclease
Descriptor: CHLORIDE ION, MAGNESIUM ION, NUCLEASE EXOG, ...
Authors:Welin, M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Nyman, T, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, Weigelt, J, Nordlund, P.
Deposit date:2011-09-16
Release date:2012-02-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Mitochondrial Endo-Exonuclease
To be Published

217705

數據於2024-03-27公開中

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