4R8X
| Crystal structure of a uricase from Bacillus fastidious | Descriptor: | Uricase | Authors: | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | Deposit date: | 2014-09-03 | Release date: | 2015-05-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.401 Å) | Cite: | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions. Appl.Microbiol.Biotechnol., 99, 2015
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1J2G
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4FSK
| Urate oxidase-azide complex in anaerobic conditions | Descriptor: | AZIDE ION, SODIUM ION, Uricase | Authors: | Gabison, L, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M, Prange, T. | Deposit date: | 2012-06-27 | Release date: | 2013-07-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Azide and Cyanide Have Different Inhibition Modes of Urate Oxidase To be Published
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2PES
| Urate Oxidase in complex with tris-dipicolinate Lutetium | Descriptor: | 8-AZAXANTHINE, LUTETIUM (III) ION, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | Authors: | Pompidor, G, Vicat, J, Kahn, R. | Deposit date: | 2007-04-03 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction. Acta Crystallogr.,Sect.D, 66, 2010
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6OE8
| The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C | Descriptor: | MALONATE ION, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | Authors: | Shi, Y, Wang, T, Zhou, X.E, Liu, Q, Jiang, Y, Xu, H.E. | Deposit date: | 2019-03-27 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy. Acta Pharmacol.Sin., 40, 2019
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7A0L
| Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | Authors: | McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A. | Deposit date: | 2020-08-09 | Release date: | 2020-12-09 | Last modified: | 2021-02-10 | Method: | NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION | Cite: | Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis. Iucrj, 8, 2021
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5FRC
| Structure of urate oxidase prepared by the 'soak-and-freeze' method under 42 bar of oxygen pressure | Descriptor: | 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ... | Authors: | Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P. | Deposit date: | 2015-12-16 | Release date: | 2016-10-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.443 Å) | Cite: | Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology. J.Appl.Crystallogr., 49, 2016
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3WLV
| Thermostable urate oxidase from Bacillus sp. TB-90 | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Hibi, T, Hayashi, Y, Itoh, T. | Deposit date: | 2013-11-14 | Release date: | 2014-06-18 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase. Biochemistry, 53, 2014
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2FUB
| Crystal structure of urate oxidase at 140 MPa | Descriptor: | 8-AZAXANTHINE, CYSTEINE, Uricase | Authors: | Colloc'h, N, Girard, E, Fourme, R. | Deposit date: | 2006-01-26 | Release date: | 2006-02-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | High pressure macromolecular crystallography: The 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly Biochim.Biophys.Acta, 1764, 2006
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4XFP
| Crystal Structure of Highly Active Mutant of Bacillus sp. TB-90 Urate Oxidase | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, SULFATE ION, ... | Authors: | Hibi, T, Hayashi, Y, Kawamura, A, Itoh, T. | Deposit date: | 2014-12-28 | Release date: | 2016-01-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Glycine Substitution of Surface Proline 287 Involves Entropic Enhancement of Bacillus sp. TB-90 Uricase Activity To be published
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7F2V
| Urate oxidase from Thermobispora bispora in apo form | Descriptor: | DIMETHYL SULFOXIDE, SULFATE ION, Uricase | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | Deposit date: | 2021-06-14 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
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7F2W
| TbUox in complex with uric acid | Descriptor: | URIC ACID, Uricase | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | Deposit date: | 2021-06-14 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
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5LL1
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6RGT
| Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-METHYL URIC ACID, ... | Authors: | Bui, S, Lowden, S.R.J, Steiner, R.A. | Deposit date: | 2019-04-17 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid To Be Published
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6RGM
| urate oxidase under 130 bar of krypton | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2019-04-17 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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5M98
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5AYJ
| Hyperthermostable mutant of Bacillus sp. TB-90 Urate Oxidase - R298C | Descriptor: | 9-METHYL URIC ACID, HEXAETHYLENE GLYCOL, SULFATE ION, ... | Authors: | Hibi, T, Kume, A, Kawamura, A, Itoh, T, Nishiya, Y. | Deposit date: | 2015-08-21 | Release date: | 2016-01-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Hyperstabilization of Tetrameric Bacillus sp. TB-90 Urate Oxidase by Introducing Disulfide Bonds through Structural Plasticity Biochemistry, 55, 2016
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5Y52
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5YJ2
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5Y2P
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2FXL
| Urate oxidase from aspergillus flavus complexed with allantoin | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Uricase | Authors: | Gabison, L, Chiadmi, M, Colloc'h, N, Prange, T. | Deposit date: | 2006-02-06 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase. Febs Lett., 580, 2006
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5YJA
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3BK8
| Urate oxidase aza-xanthine complex in cyanide | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | Authors: | Gabison, L, Prange, T, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M. | Deposit date: | 2007-12-06 | Release date: | 2008-08-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications Bmc Struct.Biol., 8, 2008
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5Z2B
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5Z27
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