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4A91	Crystal structure of the glutamyl-queuosine tRNAAsp synthetase from E. coli complexed with L-glutamate Descriptor: GLUTAMIC ACID, GLUTAMYL-Q TRNA(ASP) SYNTHETASE, ZINC ION Authors: Blaise, M, Olieric, V, Sauter, C, Lorber, B, Roy, B, Karmakar, S, Banerjee, R, Becker, H.D, Kern, D. Deposit date: 2011-11-22 Release date: 2012-01-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of Glutamyl-Queuosine Trnaasp Synthetase Complexed with L-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of Trnaasp Anticodon. J.Mol.Biol., 381, 2008
1NZJ	Crystal Structure and Activity Studies of Escherichia Coli Yadb ORF Descriptor: Hypothetical protein yadB, ZINC ION Authors: Campanacci, V, Kern, D.Y, Becker, H.D, Spinelli, S, Valencia, C, Vincentelli, R, Pagot, F, Bignon, C, Giege, R, Cambillau, C. Deposit date: 2003-02-18 Release date: 2004-04-13 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity. J.Mol.Biol., 337, 2004
4R3Z	Crystal structure of human ArgRS-GlnRS-AIMP1 complex Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ... Authors: Fu, Y, Kim, Y, Cho, Y. Deposit date: 2014-08-18 Release date: 2014-10-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (4.033 Å) Cite: Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation Proc.Natl.Acad.Sci.USA, 111, 2014
5TGT	Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa Descriptor: GLYCEROL, Glutamate--tRNA ligase, NONAETHYLENE GLYCOL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-09-28 Release date: 2016-10-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa To Be Published
8I9I	Glutamyl-tRNA synthetase from Escherichia Coli bound to Glutamate and Zinc Descriptor: GLUTAMIC ACID, Glutamate--tRNA ligase, ZINC ION Authors: Dev, A, Chongdar, N, Dasgupta, S, Basu, G. Deposit date: 2023-02-07 Release date: 2023-04-19 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Escherichia coli GluRS To Be Published
7K86	Crystal Structure of Glutamyl-tRNA synthetase (gltX) from Stenotrophomonas maltophilia Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Glutamate--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-25 Release date: 2020-10-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal Structure of Glutamyl-tRNA synthetase (gltX) from Stenotrophomonas maltophilia to be published
4P2B	Crystal structure of the apo form of the glutaminyl-tRNA synthetase catalytic domain from Toxoplasma gondii. Descriptor: Glutamine aminoacyl-tRNA synthetase, SULFATE ION Authors: van Rooyen, J.M, Belrhali, H, Hakimi, M.A. Deposit date: 2014-03-03 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of the apo form of the glutaminyl-tRNA synthetase catalytic domain from Toxoplasma gondii. To Be Published
5H4V	Structure of glutamyl-tRNA synthetase (Xoo1504) from Xanthomonas oryzae pv. oryzae Descriptor: Glutamate--tRNA ligase Authors: Doan, T.-N.-T, Ho, T.-H, Kang, L.-W. Deposit date: 2016-11-02 Release date: 2017-10-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Transcriptional expression of aminoacyl tRNA synthetase genes of Xanthomonas oryzae pv. oryzae (Xoo) on rice-leaf extract treatment and crystal structure of Xoo glutamyl-tRNA synthetase CROP PASTURE SCI, 68, 2017
1ZJW	Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ... Authors: Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J. Deposit date: 2005-05-01 Release date: 2005-06-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase. J.Biol.Chem., 280, 2005
8VC5	Crystal structure of glutamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa (Zinc bound) Descriptor: CITRATE ANION, GLYCEROL, Glutamate--tRNA ligase, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-12-13 Release date: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of glutamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa (Zinc bound) To be published
8UK6	Candida albicans glutaminyl tRNA synthetase (GLN4) in complex with N-pyrimidinyl-beta-thiophenylacrylamide Descriptor: (2E)-N-(pyrimidin-2-yl)-3-(thiophen-2-yl)prop-2-enamide, ZINC ION, glutamine--tRNA ligase Authors: Sychantha, D, Wright, G.D. Deposit date: 2023-10-12 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-beta-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chem Biol, 2024
2HZ7	Crystal structure of the Glutaminyl-tRNA synthetase from Deinococcus radiodurans Descriptor: Glutaminyl-tRNA synthetase Authors: Deniziak, M, Sauter, C, Becker, H.D, Paulus, C, Giege, R, Kern, D. Deposit date: 2006-08-08 Release date: 2007-04-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation Nucleic Acids Res., 35, 2007
3PNY	Structure of Glutamyl-tRNA synthetase from Mycobacterium tuberculosis in space group P21 Descriptor: Glutamyl-tRNA synthetase Authors: Kachalova, G.S, Laurinavichiute, D, Bartunik, H.D. Deposit date: 2010-11-20 Release date: 2011-12-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural analysis of the non-discriminating glutamyl-tRNA synthetase from Mycobacterium tuberculosis suggests minor role of anticodon recognition in tRNA(Gln) discrimination To be Published
3PNV	V369M mutant of Glutamyl-tRNA synthetase from Mycobacterium tuberculosis Descriptor: Glutamyl-tRNA synthetase Authors: Kachalova, G.S, Laurinavichiute, D, Bartunik, H.D. Deposit date: 2010-11-19 Release date: 2011-12-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural analysis of the non-discriminating glutamyl-tRNA synthetase from Mycobacterium tuberculosis suggests minor role of anticodon recognition in tRNA(Gln) discrimination To be Published
2JA2	Mycobacterium tuberculosis glutamyl-tRNA synthetase Descriptor: ACETATE ION, CHLORIDE ION, GLUTAMYL-TRNA SYNTHETASE Authors: Bourenkov, G.P, Strizhov, N, Shkolnaya, L.A, Bruning, M, Bartunik, H.D. Deposit date: 2006-11-20 Release date: 2008-10-28 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural Basis for Discriminating or Non-Discriminating Functioning of Glutamyl-tRNA Synthetases To be Published
2O5R	Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution Descriptor: CHLORIDE ION, GLYCEROL, Glutamyl-tRNA synthetase 1 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2006-12-06 Release date: 2006-12-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution To be published
2RE8	Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE Descriptor: Glutamine tRNA, Glutaminyl-tRNA synthetase, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... Authors: Bullock, T.L, Perona, J.J. Deposit date: 2007-09-25 Release date: 2008-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 105, 2008
2RD2	Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, Glutamine tRNA, Glutaminyl-tRNA synthetase, ... Authors: Bullock, T.L, Perona, J.J. Deposit date: 2007-09-20 Release date: 2008-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 105, 2008
4YE6	The crystal structure of the intact human GlnRS Descriptor: Glutamine--tRNA ligase Authors: Ognjenovic, J, Wu, J, Ling, J, Simonovic, M. Deposit date: 2015-02-23 Release date: 2016-02-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Res., 44, 2016
4YE9	The crystal structure of the G45V mutant of human GlnRS Descriptor: Glutamine--tRNA ligase Authors: Ognjenovic, J, Wu, J, Ling, J, Simonovic, M. Deposit date: 2015-02-23 Release date: 2016-02-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Res., 44, 2016
4YE8	The crystal structure of the Y57H mutant of human GlnRS Descriptor: Glutamine--tRNA ligase Authors: Ognjenovic, J, Wu, J, Ling, J, Simonovic, M. Deposit date: 2015-02-23 Release date: 2016-02-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Res., 44, 2016
5BNZ	Crystal structure of Glutamine-tRNA ligase /Glutaminyl-tRNA synthetase (GlnRS) from Pseudomonas aeruginosa Descriptor: CHLORIDE ION, Glutamine--tRNA ligase, SULFATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-05-26 Release date: 2015-06-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of Glutamine-tRNA ligase /Glutaminyl-tRNA synthetase (GlnRS) from Pseudomonas aeruginosa to be published
3AFH	Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with a glutamyl-AMP analog Descriptor: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE Authors: Ito, T, Yokoyama, S. Deposit date: 2010-03-01 Release date: 2010-06-30 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima Acta Crystallogr.,Sect.D, 66, 2010
3AII	Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... Authors: Nureki, O, Ishitani, R. Deposit date: 2010-05-14 Release date: 2010-08-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation Nucleic Acids Res., 2010
3AKZ	Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with tRNAGln and a glutamyl-AMP analog Descriptor: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, tRNAGln Authors: Ito, T, Yokoyama, S. Deposit date: 2010-07-19 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions. Nature, 467, 2010

 

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