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5H5N
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BU of 5h5n by Molmil
The crystal structure of the NS1 (H17N10) RNA-binding domain
Descriptor: Non-structural protein 1
Authors:Zhao, X, Qi, J, Xiao, H, Gao, G.F.
Deposit date:2016-11-08
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The NS1 gene from bat-derived influenza-like virus H17N10 can be rescued in influenza A PR8 backbone
J.Gen.Virol., 97, 2016
1NS1
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BU of 1ns1 by Molmil
RNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURES
Descriptor: NONSTRUCTURAL PROTEIN 1
Authors:Montelione, G.T, Chien, C.-Y, Tejero, R.
Deposit date:1997-10-02
Release date:1998-01-14
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A novel RNA-binding motif in influenza A virus non-structural protein 1.
Nat.Struct.Biol., 4, 1997
1AIL
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BU of 1ail by Molmil
N-TERMINAL FRAGMENT OF NS1 PROTEIN FROM INFLUENZA A VIRUS
Descriptor: NONSTRUCTURAL PROTEIN NS1
Authors:Liu, J, Lynch, P.A, Chien, C, Montelione, G.T, Krug, R.M, Berman, H.M.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.
Nat.Struct.Biol., 4, 1997
6ZLC
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BU of 6zlc by Molmil
Non-specific dsRNA recognition by wildtype H7N1 RNA-binding domain
Descriptor: NITRATE ION, Non-structural protein 1, RNA (5'-R(*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*U)-3'), ...
Authors:Coste, F, Wacquiez, A, Marc, D, Castaing, B.
Deposit date:2020-06-30
Release date:2020-10-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6DGK
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BU of 6dgk by Molmil
Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus
Descriptor: Non-structural protein 1
Authors:Kleinpeter, A.B, Green, T.J, Petit, C.M.
Deposit date:2018-05-17
Release date:2018-08-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.
J. Biol. Chem., 293, 2018
2N74
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BU of 2n74 by Molmil
Solution Structure of the RNA-Binding domain of non-structural protein 1 from the 1918 H1N1 influenza virus
Descriptor: Non-structural protein 1
Authors:Jureka, A.S, Kleinpeter, A.B, Cornilescu, G, Cornilescu, C.C, Schwieters, C.D, Petit, C.M.
Deposit date:2015-09-03
Release date:2015-09-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Structure, 23, 2015
2GX9
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BU of 2gx9 by Molmil
X-ray structure of influenza virus NS1 effector domain
Descriptor: NS1 Effector Domain, THIOCYANATE ION
Authors:Bornholdt, Z.A, Prasad, B.V.
Deposit date:2006-05-08
Release date:2006-05-30
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structure of influenza virus NS1 effector domain.
Nat.Struct.Mol.Biol., 13, 2006
2Z0A
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BU of 2z0a by Molmil
Crystal structure of RNA-binding domain of NS1 from influenza A virus A/crow/Kyoto/T1/2004(H5N1)
Descriptor: GLYCINE, Nonstructural protein 1, SUCCINIC ACID
Authors:Saijo, S, Kishishita, S, Kamo-Uchikubo, T, Terada, T, Shirouzu, M, Ito, H, Ito, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of RNA-binding domain of NS1 from influenza A virus A/crow/Kyoto/T1/2004(H5N1)
To be Published
5NT1
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BU of 5nt1 by Molmil
Complex of influenza A NS1 effector domain with TRIM25 coiled coil
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
Authors:Koliopoulos, M.G, Rittinger, K.
Deposit date:2017-04-27
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
4OPH
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BU of 4oph by Molmil
X-ray structure of full-length H6N6 NS1
Descriptor: Nonstructural protein 1
Authors:Carrillo, B, Choi, J.M, Bornholdt, Z.A, Sankaran, S, Rice, A.P, Prasad, B.V.V.
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.158 Å)
Cite:The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
J.Virol., 88, 2014
5NT2
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BU of 5nt2 by Molmil
Complex of influenza A NS1 with TRIM25 coiled coil domain
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
Authors:Koliopoulos, M.G, Rittinger, K.
Deposit date:2017-04-27
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.259 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
4OPA
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BU of 4opa by Molmil
X-ray structure of H6N6-NS1 delta(80-84) mutant
Descriptor: Nonstructural protein 1
Authors:Carrillo, B.
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
J.Virol., 88, 2014
2ZKO
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BU of 2zko by Molmil
Structural basis for dsRNA recognition by NS1 protein of human influenza virus A
Descriptor: GLYCEROL, Non-structural protein 1, RNA (5'-R(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3')
Authors:Yuan, Y.A.
Deposit date:2008-03-26
Release date:2008-10-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for dsRNA recognition by NS1 protein of influenza A virus
Cell Res., 19, 2009
5BXZ
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BU of 5bxz by Molmil
H17 Bat Influenza NS1 RNA Binding Domain
Descriptor: Non-structural protein 1
Authors:Kerry, P.S, Hale, B.G.
Deposit date:2015-06-09
Release date:2015-08-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.
J.Virol., 89, 2015
5BY1
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BU of 5by1 by Molmil
H18 Bat Influenza NS1 RNA Binding Domain
Descriptor: DI(HYDROXYETHYL)ETHER, Non-structural protein 1, PENTAETHYLENE GLYCOL
Authors:Kerry, P.S, Hale, B.G.
Deposit date:2015-06-09
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.
J.Virol., 89, 2015
2KKZ
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BU of 2kkz by Molmil
Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R].
Descriptor: Non-structural protein NS1
Authors:Aramini, J.M, Ma, L, Lee, H, Zhao, L, Cunningham, K, Ciccosanti, C, Janjua, H, Fang, Y, Xiao, R, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-29
Release date:2009-07-21
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R].
To be Published
3D6R
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BU of 3d6r by Molmil
Structure of an avian influenza A virus NS1 protein effector domain
Descriptor: Non-structural protein 1
Authors:Hale, B.G, Barclay, W.S, Randall, R.E, Russell, R.J.
Deposit date:2008-05-20
Release date:2008-08-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structure of an avian influenza A virus NS1 protein effector domain.
Virology, 378, 2008
6SW8
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BU of 6sw8 by Molmil
Crystal structure of the NS1 (H7N1) RNA-binding domain
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural protein 1
Authors:Coste, F, Wacquiez, A, Marc, D, Castaing, B.
Deposit date:2019-09-20
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.933 Å)
Cite:Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6SX2
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BU of 6sx2 by Molmil
dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain
Descriptor: 1,2-ETHANEDIOL, Non-structural protein 1, RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3')
Authors:Coste, F, Wacquiez, A, Marc, D, Castaing, B.
Deposit date:2019-09-24
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6SX0
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BU of 6sx0 by Molmil
Specific dsRNA recognition by wild type H7N1 NS1 RNA-binding domain
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Non-structural protein 1, ...
Authors:Coste, F, Wacquiez, A, Marc, D, Castaing, B.
Deposit date:2019-09-24
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
3EE9
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BU of 3ee9 by Molmil
Structure of NS1 effector domain
Descriptor: Non-structural protein 1, SULFATE ION
Authors:Xia, S, Monzingo, A.F, Robertus, J.D.
Deposit date:2008-09-04
Release date:2009-01-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure of NS1A effector domain from the influenza A/Udorn/72 virus.
Acta Crystallogr.,Sect.D, 65, 2009
3EE8
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BU of 3ee8 by Molmil
Structure of NS1 effector domain
Descriptor: Non-structural protein 1
Authors:Xia, S, Monzingo, A.F, Robertus, J.D.
Deposit date:2008-09-04
Release date:2009-01-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of NS1A effector domain from the influenza A/Udorn/72 virus.
Acta Crystallogr.,Sect.D, 65, 2009
3F5T
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BU of 3f5t by Molmil
X-ray Structure of H5N1 NS1
Descriptor: Nonstructural protein 1
Authors:Bornholdt, Z.A, Prasad, B.V.V.
Deposit date:2008-11-04
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
Nature, 456, 2008
6NU0
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BU of 6nu0 by Molmil
Solution NMR structure of 1918 NS1 effector domain
Descriptor: Non-structural protein 1
Authors:Shen, Q, Cho, J.H.
Deposit date:2019-01-30
Release date:2020-01-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus.
Biochem.Biophys.Res.Commun., 518, 2019
6NRL
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BU of 6nrl by Molmil
X-ray structure of H6N6-NS1 delta(80-84) R38A K41A E71G mutant
Descriptor: Non-structural protein 1
Authors:Mitra, S, Kumar, D, Hu, L, Prasad, B.V.V.
Deposit date:2019-01-23
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity.
J.Virol., 93, 2019

 

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數據於2024-04-17公開中

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