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1BVO
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BU of 1bvo by Molmil
DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
Authors:Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
Deposit date:1998-09-16
Release date:1999-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
1A66
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BU of 1a66 by Molmil
SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES
Descriptor: CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3')
Authors:Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L.
Deposit date:1998-03-06
Release date:1998-06-17
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of the core NFATC1/DNA complex.
Cell(Cambridge,Mass.), 92, 1998
1NFA
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BU of 1nfa by Molmil
HUMAN TRANSCRIPTION FACTOR NFATC DNA BINDING DOMAIN, NMR, 10 STRUCTURES
Descriptor: HUMAN TRANSCRIPTION FACTOR NFATC1
Authors:Wolfe, S.A, Zhou, P, Dotsch, V, Chen, L, You, A, Ho, S.N, Crabtree, G.R, Wagner, G, Verdine, G.L.
Deposit date:1997-01-18
Release date:1997-04-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc.
Nature, 385, 1997
2V2T
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BU of 2v2t by Molmil
X-ray structure of a NF-kB p50-RelB-DNA complex
Descriptor: 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB
Authors:Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G.
Deposit date:2007-06-07
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites.
J.Mol.Biol., 373, 2007
7CLI
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BU of 7cli by Molmil
Structure of NF-kB p52 homodimer bound to P-Selectin kB DNA fragment
Descriptor: DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*TP*CP*AP*CP*CP*CP*CP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*GP*GP*GP*GP*TP*GP*AP*CP*CP*CP*CP*TP*TP*G)-3'), Nuclear factor NF-kappa-B p52 subunit
Authors:Meshcheryakov, V.A, Wang, V.Y.-F.
Deposit date:2020-07-21
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
Elife, 12, 2023
6GGR
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BU of 6ggr by Molmil
Crystal structure of Salmonella zinc metalloprotease effector GtgA in complex with p65
Descriptor: Bacteriophage virulence determinant, CHLORIDE ION, Transcription factor p65
Authors:Jennings, E, Esposito, D, Rittinger, K, Thurston, T.
Deposit date:2018-05-03
Release date:2018-08-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B.
J. Biol. Chem., 293, 2018
3GUT
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BU of 3gut by Molmil
Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR
Descriptor: HIV-LTR Core Forward Strand, HIV-LTR Core Reverse Strand, Nuclear factor NF-kappa-B p105 subunit, ...
Authors:Stroud, J.C, Oltman, A.J, Han, A, Bates, D.L, Chen, L.
Deposit date:2009-03-30
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
J.Mol.Biol., 393, 2009
5U01
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BU of 5u01 by Molmil
Cooperative DNA binding by two RelA dimers
Descriptor: DNA (27-MER), Transcription factor p65
Authors:Ghosh, G, Huang, D.
Deposit date:2016-11-22
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated.
J. Biol. Chem., 292, 2017
8OW4
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BU of 8ow4 by Molmil
2.75 angstrom crystal structure of human NFAT1 with bound DNA
Descriptor: DNA (5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3'), Nuclear factor of activated T-cells, ...
Authors:Lopez-Sagaseta, J, Erausquin, E, Hernandez-Morales, S, Urdiciain, A, Lasarte, J.J, Lozano, T.
Deposit date:2023-04-27
Release date:2023-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:2.75 angstrom crystal structure of human NFAT1 with bound DNA
Not published
2I9T
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BU of 2i9t by Molmil
Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter
Descriptor: 5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*CP*TP*G)-3', 5'-D(*CP*AP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*CP*T)-3', Nuclear factor NF-kappa-B p105 subunit, ...
Authors:Escalante, C.R, Shen, L, Thanos, D, Aggarwal, A.K.
Deposit date:2006-09-06
Release date:2007-02-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
Structure, 10, 2002
1GJI
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BU of 1gji by Molmil
Crystal structure of c-Rel bound to DNA
Descriptor: C-REL PROTO-ONCOGENE PROTEIN, IL-2 CD28RE DNA
Authors:Huang, D.B, Chen, Y.Q, Ruetsche, M, Phelps, C.B, Ghosh, G.
Deposit date:2001-05-30
Release date:2002-05-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2.
Structure, 9, 2001
3DO7
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BU of 3do7 by Molmil
X-ray structure of a NF-kB p52/RelB/DNA complex
Descriptor: 5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3', Avian reticuloendotheliosis viral (V-rel) oncogene related B, Nuclear factor NF-kappa-B p100 subunit
Authors:Fusco, A, Huang, D.B, Miller, D, Vu, D, Ghosh, G.
Deposit date:2008-07-03
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
TO BE PUBLISHED
1SVC
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BU of 1svc by Molmil
NFKB P50 HOMODIMER BOUND TO DNA
Descriptor: DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB))
Authors:Mueller, C.W, Harrison, S.C.
Deposit date:1995-11-27
Release date:1996-06-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the NF-kappa B p50 homodimer bound to DNA.
Nature, 373, 1995
1VKX
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BU of 1vkx by Molmil
CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
Descriptor: DNA (5'-D(*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*C)-3'), PROTEIN (NF-KAPPA B P50 SUBUNIT), ...
Authors:Chen, F, Huang, D.B, Ghosh, G.
Deposit date:1997-09-17
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Nature, 391, 1998
8TKM
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BU of 8tkm by Molmil
Murine NF-kappaB p50 Rel Homology Region homodimer in complex with 17-mer kappaB DNA from human interleukin-6 (IL-6) promoter
Descriptor: 17-mer kappaB DNA, Nuclear factor NF-kappa-B p50 subunit
Authors:Zhu, N, Mealka, M, Mitchel, S, Rogers, W.E, Huxford, T.
Deposit date:2023-07-25
Release date:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
8TKN
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BU of 8tkn by Molmil
Murine NF-kappaB p50 Rel Homology Region homodimer in complex with 10-mer kappaB DNA from human Neutrophil Gelatinase-associated Lipocalin (NGAL) promoter
Descriptor: DNA A, DNA B, Nuclear factor NF-kappa-B p50 subunit
Authors:Zhu, N, Mealka, M, Mitchel, S, Rogers, W.E, Huxford, T.
Deposit date:2023-07-25
Release date:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
8TKL
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BU of 8tkl by Molmil
Murine NF-kappaB p50 Rel Homology Region homodimer in complex with a Test 16-mer kappaB-like DNA
Descriptor: Nuclear factor NF-kappa-B p50 subunit, Test 17-mer kappaB-like DNA
Authors:Mitchel, S, Mealka, M, Rogers, W.E, Milani, C, Acuna, L.M, Huxford, T.
Deposit date:2023-07-25
Release date:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
1A3Q
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BU of 1a3q by Molmil
HUMAN NF-KAPPA-B P52 BOUND TO DNA
Descriptor: DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52)
Authors:Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W.
Deposit date:1998-01-23
Release date:1998-06-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
7VUP
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BU of 7vup by Molmil
Structure of NF-kB p52 homodimer bound to +1/-1 swap P-Selectin kB DNA fragment
Descriptor: DNA (5'-D(*AP*AP*GP*GP*GP*GP*GP*AP*GP*TP*CP*CP*CP*CP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*AP*CP*TP*CP*CP*CP*CP*CP*TP*T)-3'), Nuclear factor NF-kappa-B p52 subunit
Authors:Meshcheryakov, V.A, Wang, V.Y.-F.
Deposit date:2021-11-04
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
Elife, 12, 2023
7VUQ
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BU of 7vuq by Molmil
Structure of NF-kB p52 homodimer bound to A/T-centric P-Selectin kB DNA fragment
Descriptor: DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*TP*TP*AP*CP*CP*CP*CP*CP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*GP*GP*GP*GP*GP*TP*AP*AP*CP*CP*CP*CP*TP*TP*G)-3'), Nuclear factor NF-kappa-B p52 subunit
Authors:Meshcheryakov, V.A, Wang, V.Y.-F.
Deposit date:2021-11-04
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
Elife, 12, 2023
7W7L
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BU of 7w7l by Molmil
Structure of NF-kB p52 homodimer bound to 13-mer A/T-centric P-Selectin kB DNA fragment
Descriptor: DNA (5'-D(*AP*GP*GP*GP*GP*TP*TP*AP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*TP*AP*AP*CP*CP*CP*CP*T)-3'), Nuclear factor NF-kappa-B p52 subunit
Authors:Meshcheryakov, V.A, Wang, V.Y.-F.
Deposit date:2021-12-05
Release date:2022-01-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
Elife, 12, 2023
2O93
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BU of 2o93 by Molmil
Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Descriptor: actor of activated T-cells, cytoplasmic 2, kappaB enhancer element, ...
Authors:Bates, D.L, Chen, L.
Deposit date:2006-12-13
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Structure, 16, 2008
2O61
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BU of 2o61 by Molmil
Crystal Structure of NFkB, IRF7, IRF3 bound to the interferon-b enhancer
Descriptor: 34-MER, 36-MER, Nuclear factor NF-kappa-B p105 subunit, ...
Authors:Panne, D.
Deposit date:2006-12-06
Release date:2007-07-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An Atomic Model of the Interferon-beta Enhanceosome.
Cell(Cambridge,Mass.), 129, 2007
2RAM
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BU of 2ram by Molmil
A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*(5IU)P*(5IU)P*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65)
Authors:Chen, Y.Q, Ghosh, S, Ghosh, G.
Deposit date:1997-11-23
Release date:1998-05-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Nat.Struct.Biol., 5, 1998
1IMH
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BU of 1imh by Molmil
TonEBP/DNA COMPLEX
Descriptor: 5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3', 5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3', NUCLEAR FACTOR OF ACTIVATED T CELLS 5
Authors:Stroud, J.C, Lopez-Rodriguez, C, Rao, A, Chen, L.
Deposit date:2001-05-10
Release date:2002-02-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor.
Nat.Struct.Biol., 9, 2002

 

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數據於2024-03-27公開中

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