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5NZ9
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BU of 5nz9 by Molmil
NMR structure of an EphA2-Sam fragment
Descriptor: Ephrin type-A receptor 2
Authors:Mercurio, F.A, Leone, M.
Deposit date:2017-05-12
Release date:2017-12-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors.
Sci Rep, 7, 2017
5L1M
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BU of 5l1m by Molmil
CASKIN2 SAM domain tandem
Descriptor: Caskin-2
Authors:Donaldson, L.W, Kwan, J.J, Saridakis, V.
Deposit date:2016-07-29
Release date:2016-08-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.
Cell Commun. Signal, 14, 2016
1B4F
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BU of 1b4f by Molmil
OLIGOMERIC STRUCTURE OF THE HUMAN EPHB2 RECEPTOR SAM DOMAIN
Descriptor: EPHB2
Authors:Thanos, C.D, Goodwill, K.E, Bowie, J.U.
Deposit date:1998-12-20
Release date:1999-02-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Oligomeric structure of the human EphB2 receptor SAM domain.
Science, 283, 1999
1F0M
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BU of 1f0m by Molmil
MONOMERIC STRUCTURE OF THE HUMAN EPHB2 SAM (STERILE ALPHA MOTIF) DOMAIN
Descriptor: EPHRIN TYPE-B RECEPTOR 2
Authors:Thanos, C.D, Faham, S, Goodwill, K.E, Cascio, D, Phillips, M, Bowie, J.U.
Deposit date:2000-05-16
Release date:2000-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Monomeric structure of the human EphB2 sterile alpha motif domain.
J.Biol.Chem., 274, 1999
5J8Y
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BU of 5j8y by Molmil
Crystal structure of the Scm-SAM and Sfmbt-SAM heterodimer
Descriptor: Polycomb protein Scm, Polycomb protein Sfmbt
Authors:Frey, F, Benda, C, Mueller, J.
Deposit date:2016-04-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC.
Genes Dev., 30, 2016
4IS7
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BU of 4is7 by Molmil
Crystal Structure of the CASKIN2 SAM Domain Tandem
Descriptor: Caskin-2
Authors:Donaldson, L.W, Kwan, J.J.
Deposit date:2013-01-16
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Crystal Structure of the CASKIN2 SAM Domain Tandem
To be Published
2MYQ
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BU of 2myq by Molmil
NMR structure of an Odin-Sam1 fragment
Descriptor: Ankyrin repeat and SAM domain-containing protein 1A
Authors:Mercurio, F.A, Leone, M.
Deposit date:2015-01-30
Release date:2015-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.
Chembiochem, 16, 2015
4NL9
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BU of 4nl9 by Molmil
Crystal structure of the human Anks3-SAM/Anks6-SAM heterodimer
Descriptor: Ankyrin repeat and SAM domain-containing protein 3, Ankyrin repeat and SAM domain-containing protein 6, MAGNESIUM ION
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2013-11-13
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Bmc Struct.Biol., 14, 2014
4NJ8
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BU of 4nj8 by Molmil
Crystal structure of the human ANKS3 SAM Domain L52A mutant
Descriptor: Ankyrin repeat and SAM domain-containing protein 3
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2013-11-08
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Bmc Struct.Biol., 14, 2014
8ATJ
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BU of 8atj by Molmil
Crystal Structure of Shank2-SAM domain
Descriptor: CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ...
Authors:Bento, I, Gracia Alai, M, Kreienkamp, J.-H.
Deposit date:2022-08-23
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.117 Å)
Cite:Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry, 2022
8B10
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Crystal Structure of Shank2-SAM mutant domain - L1800W
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Bento, I, Gracia Alai, M, Kreienkamp, J.-H.
Deposit date:2022-09-08
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry, 2022
2QKQ
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BU of 2qkq by Molmil
Structure of the SAM Domain of Human Ephrin Type-B Receptor 4
Descriptor: CHLORIDE ION, Ephrin type-B receptor 4
Authors:Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-11
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SAM Domain of Human Ephrin Type-B Receptor 4 (EPHB4)
TO BE PUBLISHED
8J1I
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BU of 8j1i by Molmil
Crystal Structure of EphA8/SASH1 Complex
Descriptor: Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1
Authors:Liu, W, Li, J, Ding, Y.
Deposit date:2023-04-12
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of EphA8 and SASH1 complex at 1.60 Angstroms resolution
To Be Published
3HIL
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BU of 3hil by Molmil
SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1)
Descriptor: CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION
Authors:Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-05-20
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1).
To be Published
5ZRX
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BU of 5zrx by Molmil
Crystal Structure of EphA2/SHIP2 Complex
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5ZRY
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BU of 5zry by Molmil
Crystal Structure of EphA6/Odin Complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ...
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
1PK3
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BU of 1pk3 by Molmil
Scm SAM domain
Descriptor: BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA
Authors:Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U.
Deposit date:2003-06-04
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
6F7M
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BU of 6f7m by Molmil
NMR structure of EphA2-Sam stapled peptides (S13ST)
Descriptor: Ephrin type-A receptor 2
Authors:Mercurio, F.A, Leone, M.
Deposit date:2017-12-11
Release date:2018-08-01
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
6FXF
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BU of 6fxf by Molmil
Crystal structure of the SAM domain of murine SLy1
Descriptor: SAM and SH3 domain-containing protein 3
Authors:Kukuk, L.K, Granzin, J, Batra-Safferling, R, Koenig, B.W.
Deposit date:2018-03-09
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
Sci Rep, 9, 2019
6G8O
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BU of 6g8o by Molmil
Solution structure of the cross-linked SAM domain dimer of murine SLy1
Descriptor: SAM and SH3 domain-containing protein 3
Authors:Kukuk, L.K, Dingley, A.J, Koenig, B.W.
Deposit date:2018-04-09
Release date:2019-01-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
Sci Rep, 9, 2019
3KKA
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BU of 3kka by Molmil
Co-crystal structure of the sam domains of EPHA1 AND EPHA2
Descriptor: CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2
Authors:Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-11-05
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2
To be Published
4PZO
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BU of 4pzo by Molmil
Crystal structure of PHC3 SAM L967R
Descriptor: Polyhomeotic-like protein 3
Authors:Nanyes, D.R, Junco, S.E, Taylor, A.B, Robinson, A.K, Patterson, N.L, Shivarajpur, A, Halloran, J, Hale, S.M, Kaur, Y, Hart, P.J, Kim, C.A.
Deposit date:2014-03-31
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motif.
Proteins, 82, 2014
1SGG
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BU of 1sgg by Molmil
THE SOLUTION STRUCTURE OF SAM DOMAIN FROM THE RECEPTOR TYROSINE KINASE EPHB2, NMR, 10 STRUCTURES
Descriptor: EPHRIN TYPE-B RECEPTOR 2
Authors:Smalla, M, Schmieder, P, Kelly, M, Ter Laak, A, Krause, G, Ball, L, Wahl, M, Bork, P, Oschkinat, H.
Deposit date:1999-01-08
Release date:1999-10-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites.
Protein Sci., 8, 1999
4PZN
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BU of 4pzn by Molmil
Crystal structure of PHC3 SAM L971E
Descriptor: 1,2-ETHANEDIOL, Polyhomeotic-like protein 3
Authors:Nanyes, D.R, Junco, S.E, Taylor, A.B, Robinson, A.K, Patterson, N.L, Shivarajpur, A, Halloran, J, Hale, S.M, Kaur, Y, Hart, P.J, Kim, C.A.
Deposit date:2014-03-31
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motif.
Proteins, 82, 2014
3SEN
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BU of 3sen by Molmil
Structure of Caskin1 Tandem SAMs
Descriptor: Caskin-1, POTASSIUM ION
Authors:Stafford, R.L, Bowie, J.U.
Deposit date:2011-06-10
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK.
Structure, 19, 2011

 

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數據於2024-04-24公開中

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