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1A25
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BU of 1a25 by Molmil
C2 DOMAIN FROM PROTEIN KINASE C (BETA)
Descriptor: CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA)
Authors:Sutton, R.B, Sprang, S.R.
Deposit date:1998-01-16
Release date:1998-05-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
8C5H
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BU of 8c5h by Molmil
NbSyt1 anti-(rat Synaptotagmin-1) nanobody bound to target cytosolic domain of Synaptotagmin-1
Descriptor: CALCIUM ION, GLYCEROL, NbSyt1 nanobody, ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2023-01-09
Release date:2023-08-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Small Methods, 7, 2023
6IEJ
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BU of 6iej by Molmil
The C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholine
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CALCIUM ION, Cytosolic phospholipase A2, ...
Authors:Hirano, Y, Gao, Y.G, Stephenson, D.J, Vu, N.T, Malinina, L, Chalfant, C.E, Patel, D.J, Brown, R.E.
Deposit date:2018-09-14
Release date:2019-05-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife, 8, 2019
1K5W
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BU of 1k5w by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE
Descriptor: CALCIUM ION, Synaptotagmin I
Authors:Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J.
Deposit date:2001-10-12
Release date:2002-01-23
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
4DNL
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BU of 4dnl by Molmil
Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
Descriptor: Protein kinase C alpha type, SODIUM ION
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2012-02-08
Release date:2012-02-22
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
To be published
7JOF
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BU of 7jof by Molmil
Calcium-bound C2A Domain from Human Dysferlin
Descriptor: CALCIUM ION, Isoform 6 of Dysferlin
Authors:Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S.
Deposit date:2020-08-06
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
1BCI
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BU of 1bci by Molmil
C2 DOMAIN OF CYTOSOLIC PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: CALCIUM ION, CYTOSOLIC PHOSPHOLIPASE A2
Authors:Xu, G.Y, Mcdonagh, T, Yu, H.A, Nalefski, E.A, Clark, J.D, Cumming, D.A.
Deposit date:1998-04-30
Release date:1998-11-25
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2.
J.Mol.Biol., 280, 1998
7K6B
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BU of 7k6b by Molmil
Solution Structure of the Dysferlin C2A Domain in its Calcium-free State
Descriptor: Isoform 15 of Dysferlin
Authors:Wang, Y, Mercier, P, Santamaria, L, Shaw, G.S.
Deposit date:2020-09-19
Release date:2021-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
7KRB
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BU of 7krb by Molmil
Solution Structure of the Dysferlin C2A Domain in its Calcium-bound State
Descriptor: Isoform 15 of Dysferlin
Authors:Wang, Y, Mercier, P, Santamaria, L, Shaw, G.S.
Deposit date:2020-11-19
Release date:2021-01-27
Method:SOLUTION NMR
Cite:Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
1BYN
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BU of 1byn by Molmil
SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I
Descriptor: CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I)
Authors:Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J.
Deposit date:1998-10-18
Release date:1998-10-21
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
Biochemistry, 37, 1998
4V29
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BU of 4v29 by Molmil
The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions
Descriptor: AT3G17980, CALCIUM ION
Authors:Diaz, M, Albert, A.
Deposit date:2014-10-07
Release date:2014-12-17
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:C2-Domain Abscisic Acid-Related Proteins Mediate the Interaction of Pyr/Pyl/Rcar Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic Acid Sensitivity in Arabidopsis.
Plant Cell, 26, 2014
4WEE
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BU of 4wee by Molmil
High-resolution structure of Synaptotagmin 1 C2A
Descriptor: SODIUM ION, SULFATE ION, Synaptotagmin-1
Authors:Sutton, R.B, Fuson, K.L.
Deposit date:2014-09-09
Release date:2014-10-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.891 Å)
Cite:High-resolution structure of Synaptotagmin 1 C2A
To Be Published
4V11
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BU of 4v11 by Molmil
Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84
Descriptor: CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ...
Authors:Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R.
Deposit date:2014-09-22
Release date:2015-02-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
3RPB
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BU of 3rpb by Molmil
THE C2B-DOMAIN OF RABPHILIN: STRUCTURAL VARIATIONS IN A JANUS-FACED DOMAIN
Descriptor: RABPHILIN 3-A
Authors:Ubach, J, Garcia, J, Nittler, M.P, Sudhof, T.C, Rizo, J.
Deposit date:1999-04-19
Release date:1999-12-23
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the Janus-faced C2B domain of rabphilin.
Nat.Cell Biol., 1, 1999
2UZP
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BU of 2uzp by Molmil
Crystal structure of the C2 domain of human protein kinase C gamma.
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, COBALT (II) ION, ...
Authors:Pike, A.C.W, Amos, A, Johansson, C, Sobott, F, Savitsky, P, Berridge, G, Fedorov, O, Umeano, C, Gorrec, F, Bunkoczi, G, Debreczeni, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S.
Deposit date:2007-04-30
Release date:2007-05-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
7U4Q
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BU of 7u4q by Molmil
Human Synaptotagmin-1 C2A Y181F Ca2+ bound
Descriptor: CALCIUM ION, Synaptotagmin-1
Authors:Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B.
Deposit date:2022-02-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Human Synaptotagmin-1 C2A Y181F Ca2+ bound
To Be Published
7TUA
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BU of 7tua by Molmil
Human Synaptotagmin-1 C2B Y312F without Ca2+
Descriptor: SULFATE ION, Synaptotagmin
Authors:Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B.
Deposit date:2022-02-02
Release date:2023-03-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Human Synaptotagmin-1 C2B Y312F without Ca2+
To Be Published
7TX9
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BU of 7tx9 by Molmil
Human Synaptotagmin-1 C2B Y312F Ca2+ bound
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B.
Deposit date:2022-02-08
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Human Synaptotagmin-1 C2B Y312F Ca2+ bound
To Be Published
7A1R
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BU of 7a1r by Molmil
Crystal structure of the C2B domain of Trypanosoma brucei extended synaptotagmin (E-Syt)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Dong, G.
Deposit date:2020-08-13
Release date:2021-06-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei .
Iscience, 24, 2021
3GPE
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BU of 3gpe by Molmil
Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2
Descriptor: CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ...
Authors:Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N.
Deposit date:2009-03-23
Release date:2009-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
5CCJ
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BU of 5ccj by Molmil
Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain
Descriptor: GLYCEROL, SULFATE ION, Synaptotagmin-1
Authors:Zhou, Q, Zhao, M, Brunger, A.T.
Deposit date:2015-07-02
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.
Nature, 525, 2015
4RJ9
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BU of 4rj9 by Molmil
Structure of a plant specific C2 domain protein, OsGAP1 from rice
Descriptor: C2 domain-containing protein-like, POTASSIUM ION
Authors:Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M.
Deposit date:2014-10-08
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1).
J.Biol.Chem., 290, 2015
7ATP
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BU of 7atp by Molmil
2.0 angstrom structure in complex with Ca of plant Extended Synaptotagmin 1, C2A domain
Descriptor: CALCIUM ION, CHLORIDE ION, Synaptotagmin-1, ...
Authors:Benavente, J.L, Albert, A.
Deposit date:2020-10-30
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites.
Life Sci Alliance, 4, 2021
7AS6
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BU of 7as6 by Molmil
2.0 angstrom structure of plant Extended Synaptotagmin 1, C2A domain
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Benavente, J.L, Albert, A.
Deposit date:2020-10-27
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites.
Life Sci Alliance, 4, 2021
4TS6
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BU of 4ts6 by Molmil
Crystal structure of the RIM C2A domain from Drosophila.
Descriptor: GLYCEROL, Rab3 interacting molecule variant 2
Authors:Hatzopoulos, G.N, Shiroma, J, Vakonakis, I.
Deposit date:2014-06-18
Release date:2015-07-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of the RIM C2A domain from Drosophila.
To Be Published

217705

數據於2024-03-27公開中

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