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6PEW
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BU of 6pew by Molmil
CryoEM Plasmodium falciparum glutamine synthetase
Descriptor: Glutamine synthetase
Authors:Ho, C.M, Lai, M, Zhou, Z.H.
Deposit date:2019-06-21
Release date:2019-12-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu.
Nat.Methods, 17, 2020
4XYC
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BU of 4xyc by Molmil
NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES
Descriptor: 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1
Authors:Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E.
Deposit date:2015-02-02
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies.
Bioorg.Med.Chem.Lett., 25, 2015
5LDF
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BU of 5ldf by Molmil
Maltose binding protein genetically fused to dodecameric glutamine synthetase
Descriptor: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Coscia, F, Petosa, C, Schoehn, G.
Deposit date:2016-06-25
Release date:2016-08-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
3NG0
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BU of 3ng0 by Molmil
Crystal Structure of Glutamine Synthetase from Synechocystis sp. PCC 6803
Descriptor: Glutamine synthetase, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Saelices, L, Cascio, D, Florencio, F.J, Muro-Pastor, M.I.
Deposit date:2010-06-10
Release date:2011-06-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Glutamine Synthetase from Synechocystis sp. PCC 6803
To be Published
7EVT
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BU of 7evt by Molmil
Crystal structure of the N-terminal degron-truncated human glutamine synthetase
Descriptor: Glutamine synthetase
Authors:Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T.
Deposit date:2021-05-22
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of N-terminal degron-truncated human glutamine synthetase.
Acta Crystallogr.,Sect.F, 77, 2021
8DNU
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BU of 8dnu by Molmil
Human Brain Glutamine Synthetase
Descriptor: Glutamine synthetase, MANGANESE (II) ION
Authors:Tringides, M.L.
Deposit date:2022-07-11
Release date:2022-11-16
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
4IS4
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BU of 4is4 by Molmil
The glutamine synthetase from the dicotyledonous plant M. truncatula is a decamer
Descriptor: Glutamine synthetase
Authors:Seabra, A.R, Carvalho, H, Pereira, P.J.B.
Deposit date:2013-01-16
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture.
Acta Crystallogr.,Sect.D, 70, 2014
3FKY
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BU of 3fky by Molmil
Crystal structure of the glutamine synthetase Gln1deltaN18 from the yeast Saccharomyces cerevisiae
Descriptor: CITRATE ANION, Glutamine synthetase
Authors:He, Y.X, Gui, L, Liu, Y.Z, Du, Y, Zhou, Y.Y, Li, P, Zhou, C.Z.
Deposit date:2008-12-18
Release date:2009-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly
Proteins, 76, 2009
8ECY
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BU of 8ecy by Molmil
cryoEM structure of bovine bestrophin-2 and glutamine synthetase complex
Descriptor: Bestrophin, CALCIUM ION, CHLORIDE ION, ...
Authors:Owji, A.P, Kittredge, A.K, Yang, T.
Deposit date:2022-09-02
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Bestrophin-2 and glutamine synthetase form a complex for glutamate release.
Nature, 611, 2022
4S0R
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BU of 4s0r by Molmil
Structure of GS-TnrA complex
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
Authors:Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K.
Deposit date:2015-01-04
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
4S17
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BU of 4s17 by Molmil
The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
Descriptor: ACETATE ION, Glutamine synthetase, MAGNESIUM ION
Authors:Cuff, M, Tan, K, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2015-01-08
Release date:2015-01-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
To be Published
8FBP
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BU of 8fbp by Molmil
Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
Descriptor: Glutamine synthetase
Authors:Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-11-29
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
To Be Published
2OJW
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BU of 2ojw by Molmil
Crystal structure of human glutamine synthetase in complex with ADP and phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
Authors:Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-01-15
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
2GLS
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BU of 2gls by Molmil
REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION
Descriptor: GLUTAMINE SYNTHETASE, MANGANESE (II) ION
Authors:Eisenberg, D, Almassy, R.J, Yamashita, M.M.
Deposit date:1989-05-19
Release date:1989-10-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Refined atomic model of glutamine synthetase at 3.5 A resolution.
J.Biol.Chem., 264, 1989
5ZLP
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BU of 5zlp by Molmil
Crystal structure of glutamine synthetase from helicobacter pylori
Descriptor: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Joo, H.K, Lee, J.Y.
Deposit date:2018-03-29
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
5ZLI
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BU of 5zli by Molmil
Crystal structure of glutamine synthetase from helicobacter pylori
Descriptor: Glutamine synthetase
Authors:Joo, H.K, Lee, J.Y.
Deposit date:2018-03-28
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
2QC8
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BU of 2qc8 by Molmil
Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ...
Authors:Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-06-19
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
2LGS
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BU of 2lgs by Molmil
FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE
Descriptor: GLUTAMIC ACID, GLUTAMINE SYNTHETASE, MANGANESE (II) ION
Authors:Liaw, S.-H, Eisenberg, D.
Deposit date:1994-08-05
Release date:1994-11-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.
Proc.Natl.Acad.Sci.USA, 90, 1993
2UU7
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BU of 2uu7 by Molmil
Crystal structure of apo glutamine synthetase from dog (Canis familiaris)
Descriptor: CHLORIDE ION, GLUTAMINE SYNTHETASE, MAGNESIUM ION
Authors:Krajewski, W.W, Jones, T.A, Mowbray, S.L.
Deposit date:2007-02-28
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design.
J.Mol.Biol., 375, 2008
1HTO
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BU of 1hto by Molmil
CRYSTALLOGRAPHIC STRUCTURE OF A RELAXED GLUTAMINE SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GLUTAMINE SYNTHETASE, ...
Authors:Gill, H.S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2001-01-01
Release date:2002-07-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation.
Biochemistry, 41, 2002
1HTQ
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BU of 1htq by Molmil
Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis
Descriptor: ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ...
Authors:Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2001-01-01
Release date:2002-07-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation.
Biochemistry, 41, 2002
2WGS
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BU of 2wgs by Molmil
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor.
Descriptor: 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1
Authors:Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L.
Deposit date:2009-04-27
Release date:2009-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors.
J.Mol.Biol., 393, 2009
2WHI
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BU of 2whi by Molmil
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor and L-methionine-S- sulfoximine phosphate.
Descriptor: 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ...
Authors:Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L.
Deposit date:2009-05-05
Release date:2009-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors.
J.Mol.Biol., 393, 2009
1F1H
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BU of 1f1h by Molmil
CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Gill, H.S, Eisenberg, D.
Deposit date:2000-05-19
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Biochemistry, 40, 2001
1F52
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CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE SYNTHETASE, ...
Authors:Gill, H.S, Pfluegl, G.M.U, Eisenberg, D.
Deposit date:2000-06-12
Release date:2000-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Biochemistry, 40, 2001

 

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