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2PTL
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BU of 2ptl by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN-BINDING DOMAIN OF PROTEIN L. COMPARISON WITH THE IGG-BINDING DOMAINS OF PROTEIN G
Descriptor: PROTEIN L
Authors:Wikstroem, M, Drakenberg, T, Forsen, S, Sjoebring, U, Bjoerck, L.
Deposit date:1994-08-12
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G.
Biochemistry, 33, 1994
1YMH
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BU of 1ymh by Molmil
anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W
Descriptor: Fab 16D9D6, heavy chain, light chain, ...
Authors:Granata, V, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A.
Deposit date:2005-01-21
Release date:2005-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Comparison of the crystallization and crystal packing of two Fab single-site mutant protein L complexes.
Acta Crystallogr.,Sect.D, 61, 2005
2JZP
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BU of 2jzp by Molmil
NMR solution structure of Kx5Q ProtL mutant
Descriptor: Protein L
Authors:Lopez-Mendez, N, Tadeo, X, Castano, D, Pons, M, Millet Aguilar-Galindo, O.
Deposit date:2008-01-11
Release date:2009-01-13
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Protein stabilization and the hofmeister effect: the role of hydrophobic solvation
Biophys.J., 97, 2009
2KAC
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BU of 2kac by Molmil
NMR solution structure of KX6E protL mutant
Descriptor: Protein L
Authors:Lopez-Mendez, B, Tadeo, X, Pons, M, Millet, O.
Deposit date:2008-11-04
Release date:2009-10-20
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis for the aminoacid composition of proteins from halophilic archea
Plos Biol., 7, 2009
1HZ5
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BU of 1hz5 by Molmil
CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS, WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
Descriptor: PROTEIN L, ZINC ION
Authors:O'Neill, J.W, Kim, D.E, Baker, D, Zhang, K.Y.J.
Deposit date:2001-01-23
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1HZ6
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BU of 1hz6 by Molmil
CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
Descriptor: PROTEIN L
Authors:O'Neill, J.W, Kim, D.E, Baker, D, Zhang, K.Y.J.
Deposit date:2001-01-23
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1JML
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BU of 1jml by Molmil
Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design
Descriptor: Protein L, ZINC ION
Authors:O'Neill, J.W, Kuhlman, B, Kim, D.E, Zhang, K.Y.J, Baker, D.
Deposit date:2001-07-19
Release date:2001-10-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conversion of monomeric protein L to an obligate dimer by computational protein design.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K50
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BU of 1k50 by Molmil
A V49A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus
Descriptor: Protein L
Authors:O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K53
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BU of 1k53 by Molmil
Monomeric Protein L B1 Domain with a G15A Mutation
Descriptor: Protein L, ZINC ION
Authors:O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K51
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BU of 1k51 by Molmil
A G55A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus
Descriptor: Protein L, ZINC ION
Authors:O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K52
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BU of 1k52 by Molmil
Monomeric Protein L B1 Domain with a K54G mutation
Descriptor: Protein L, ZINC ION
Authors:O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1KH0
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BU of 1kh0 by Molmil
Accurate Computer Base Design of a New Backbone Conformation in the Second Turn of Protein L
Descriptor: protein L
Authors:O'Neill, J.W, Kuhlman, B, Kim, D.E, Zhang, K.Y, Baker, D.
Deposit date:2001-11-28
Release date:2002-01-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Accurate computer-based design of a new backbone conformation in the second turn of protein L.
J.Mol.Biol., 315, 2002
1YNT
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BU of 1ynt by Molmil
Structure of the monomeric form of T. gondii SAG1 surface antigen bound to a human Fab
Descriptor: 4F11E12 Fab variable heavy chain region, 4F11E12 Fab variable light chain region, CADMIUM ION, ...
Authors:Graille, M, Stura, E.A, Bossus, M, Muller, B.H, Letourneur, O, Battail-Poirot, N, Sibai, G, Rolland, D, Le Du, M.H, Ducancel, F.
Deposit date:2005-01-25
Release date:2005-12-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response
J.Mol.Biol., 354, 2005
1HEZ
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BU of 1hez by Molmil
Structure of P. magnus protein L bound to a human IgM Fab.
Descriptor: HEAVY CHAIN OF IG, IMIDAZOLE, KAPPA LIGHT CHAIN OF IG, ...
Authors:Graille, M, Stura, E.A, Housden, N.G, Bottomley, S.P, Taussig, M.J, Sutton, B.J, Gore, M.G, Charbonnier, J.B.
Deposit date:2000-11-27
Release date:2001-08-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9, 2001
4HJG
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BU of 4hjg by Molmil
Meditope-enabled trastuzumab
Descriptor: Immunoglobulin G-binding protein A, Protein L fragment, Trastuzumab heavy chain, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-10-12
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKZ
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BU of 4hkz by Molmil
Trastuzumab Fab complexed with Protein L and Protein A fragments
Descriptor: CHLORIDE ION, Immunoglobulin G-binding protein A, Protein L fragment, ...
Authors:Avery, K.N, Zer, C, Bzymek, K.P, Williams, J.C.
Deposit date:2012-10-15
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IOI
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BU of 4ioi by Molmil
Meditope-enabled trastuzumab in complex with CQFDLSTRRLKC
Descriptor: Immunoglobulin G-binding protein A, Protein L, Trastuzumab heavy chain, ...
Authors:Bzymek, K.P, Zer, C, Avery, K.N, Williams, J.C.
Deposit date:2013-01-07
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5U5F
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BU of 5u5f by Molmil
MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT IN COMPLEX WITH (Ac) CQFDA(PH)2STRRLRCGGSK
Descriptor: 5-DIPHENYL LONG MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB FAB HEAVY CHAIN, ...
Authors:Bzymek, K.P, Avery, K.N, Zer, C, Williams, J.C.
Deposit date:2016-12-06
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Meditope Enabled Trastuzumab I83E Variant In Complex With (Ac)Cqfda(Ph)2Strrlrcggsk
To Be Published
5U6A
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BU of 5u6a by Molmil
CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE
Descriptor: Heavy Chain, Immunoglobulin G binding protein A, Light Chain, ...
Authors:Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
Deposit date:2016-12-07
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.736 Å)
Cite:Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-PEG3-Meditope
To Be Published
5U3D
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BU of 5u3d by Molmil
STRUCTURE OF MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT
Descriptor: Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB FAB HEAVY CHAIN, MEMAB TRASTUZUMAB FAB LIGHT CHAIN I83E, ...
Authors:Bzymek, K.P, Avery, K.N, Zer, C, Williams, J.C.
Deposit date:2016-12-01
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Meditope Enabled Trastuzumab I83E Variant
To Be Published
5U5M
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BU of 5u5m by Molmil
CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE
Descriptor: AZIDO-PEG4-MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB, ...
Authors:Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
Deposit date:2016-12-06
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-Meditope
To Be Published
6BAH
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BU of 6bah by Molmil
Trastuzumab Fab v3 with 5-diphenyl meditope variant
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-12
Release date:2018-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6BAE
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BU of 6bae by Molmil
Trastuzumab Fab v3 in complex with CQFDLSTRRLKC
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-12
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6B9Y
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BU of 6b9y by Molmil
Trastuzumab Fab v3 in complex with 5-phenyl meditope variant
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-11
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6B9Z
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BU of 6b9z by Molmil
Trastuzumab Fab v3
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-11
Release date:2018-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018

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数据于2024-03-27公开中

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