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5GPH
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BU of 5gph by Molmil
Solution structure of the Pin1-PPIase (S138A) mutant
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Tochio, N, Wang, J, Tate, S.
Deposit date:2016-08-02
Release date:2017-08-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the Pin1-PPIase (S138A) mutant
To Be Published
1J6Y
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BU of 1j6y by Molmil
Solution structure of Pin1At from Arabidopsis thaliana
Descriptor: peptidyl-prolyl cis-trans isomerase
Authors:Landrieu, I, Wieruszeski, J.M, Wintjens, R, Inze, D, Lippens, G.
Deposit date:2001-05-15
Release date:2002-08-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure of the Single-domain Prolyl Cis/Trans Isomerase PIN1At from Arabidopsis thaliana
J.Mol.Biol., 320, 2002
5EZ1
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BU of 5ez1 by Molmil
Crystal Structure of Cell Binding Factor 2 from Helicobacter pylori in complex with I2CA
Descriptor: 1H-indole-2-carboxylic acid, Putative peptidyl-prolyl cis-trans isomerase HP_0175
Authors:Sun, Y.J, Chu, C.H, Tsai, Y.C.
Deposit date:2015-11-26
Release date:2016-03-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Helicobacter pylori cell binding factor 2: Insights into domain motion.
J.Struct.Biol., 194, 2016
6BHF
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BU of 6bhf by Molmil
Crystal structure of the petidylprolyl cis,trans-isomerase from Helicobacter pylori
Descriptor: Putative peptidyl-prolyl cis-trans isomerase HP_0175
Authors:Yaseen, A, Audette, G.F.
Deposit date:2017-10-30
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural flexibility in the Helicobacter pylori peptidyl-prolyl cis,trans-isomerase HP0175 is achieved through an extension of the chaperone helices.
J. Struct. Biol., 204, 2018
6DUN
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BU of 6dun by Molmil
Crystal Structure Analysis of PIN1
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, TRIHYDROXYARSENITE(III)
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2018-06-21
Release date:2019-03-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells.
Nat Commun, 9, 2018
5TVL
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BU of 5tvl by Molmil
Crystal structure of foldase protein PrsA from Streptococcus pneumoniae str. Canada MDR_19A
Descriptor: CHLORIDE ION, Foldase protein PrsA, GLYCEROL, ...
Authors:Borek, D, Yim, V, Kudritska, M, Wawrzak, Z, Stogios, P.J, Otwinowski, Z, Savchenko, A, Anderson, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-11-09
Release date:2016-11-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of foldase protein PrsA from Streptococcus pneumoniae str. Canada MDR_19A
To Be Published
6VJ4
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BU of 6vj4 by Molmil
1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
Descriptor: Peptidylprolyl isomerase PrsA
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Wiersum, G, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-01-14
Release date:2020-02-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
To Be Published
6GMP
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BU of 6gmp by Molmil
CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF TBPAR42
Descriptor: PARVULIN 42
Authors:Hoenig, D, Rute, A, Hofmann, E, Bayer, P, Gasper, R.
Deposit date:2018-05-28
Release date:2019-03-20
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural Analysis of the 42 kDa Parvulin ofTrypanosoma brucei.
Biomolecules, 9, 2019
8HM4
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BU of 8hm4 by Molmil
Crystal structure of PPIase
Descriptor: Peptidylprolyl isomerase
Authors:Xu, J.H, Chen, Z, Gao, X.
Deposit date:2022-12-02
Release date:2023-11-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome.
Nat Microbiol, 9, 2024
8SOT
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BU of 8sot by Molmil
Structure of the PPIase domain of borrelial BB0108
Descriptor: Basic membrane protein, GLYCEROL
Authors:Shakya, A.K, Herzberg, O.
Deposit date:2023-04-30
Release date:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A multi-domain microbial protein facilitates immune evasion in Lyme disease pathogens
To be published
2JZV
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BU of 2jzv by Molmil
Solution structure of S. aureus PrsA-PPIase
Descriptor: Foldase protein prsA
Authors:Seppala, R, Tossavainen, H, Heikkinen, S, Koskela, H, Kontinen, V, Permi, P.
Deposit date:2008-01-21
Release date:2009-01-20
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA - Implications for the catalytic mechanism of parvulins.
Bmc Struct.Biol., 9, 2009
1NMW
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BU of 1nmw by Molmil
Solution structure of the PPIase domain of human Pin1
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION
Authors:Bayer, E, Goettsch, S, Mueller, J.W, Griewel, B, Guiberman, E, Mayr, L, Bayer, P.
Deposit date:2003-01-12
Release date:2003-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING.
J.Biol.Chem., 278, 2003
2LJ4
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BU of 2lj4 by Molmil
Solution structure of the TbPIN1
Descriptor: Peptidyl-prolyl cis-trans isomerase/rotamase, putative
Authors:Sun, L, Lin, D, Zhao, Y.
Deposit date:2011-09-06
Release date:2012-08-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structural analysis of the single-domain parvulin TbPin1.
Plos One, 7, 2012
2N87
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BU of 2n87 by Molmil
Solution structure of the PPIase domain of TbPar42
Descriptor: Uncharacterized protein
Authors:Rehic, E, Bayer, P.
Deposit date:2015-10-05
Release date:2016-10-12
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.
Biomolecules, 9, 2019
4TNS
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BU of 4tns by Molmil
Structure of Pin1 PPIase domain bound with all-trans retinoic acid
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, RETINOIC ACID
Authors:Li, W.Z, Zhang, Y.
Deposit date:2014-06-04
Release date:2015-04-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structure of Pin1 PPIase domain bound with all-trans retinoic acid
To Be Published
4TYO
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BU of 4tyo by Molmil
PPIase in complex with a non-phosphate small molecule inhibitor.
Descriptor: 3-(6-fluoro-1H-benzimidazol-2-yl)-N-(naphthalen-2-ylcarbonyl)-D-alanine, GLYCEROL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Greasley, S.E, Ferre, R.A.
Deposit date:2014-07-08
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-based design of novel human Pin1 inhibitors (III): Optimizing affinity beyond the phosphate recognition pocket.
Bioorg.Med.Chem.Lett., 24, 2014
2PV2
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BU of 2pv2 by Molmil
Crystallographic Structure of SurA first peptidyl-prolyl isomerase domain complexed with peptide NFTLKFWDIFRK
Descriptor: C-peptide, Chaperone surA
Authors:Xu, X, McKay, D.B.
Deposit date:2007-05-09
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Periplasmic Bacterial Molecular Chaperone SurA Adapts its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues.
J.Mol.Biol., 373, 2007
2PV1
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BU of 2pv1 by Molmil
Crystallographic Structure of SurA first peptidyl-prolyl isomerase domain complexed with peptide WEYIPNV
Descriptor: Chaperone surA, Glycosyl transferase, group 1
Authors:Xu, X, McKay, D.B.
Deposit date:2007-05-09
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Periplasmic Bacterial Molecular Chaperone SurA Adapts its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues.
J.Mol.Biol., 373, 2007
2RUC
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BU of 2ruc by Molmil
Solution structure of the peptidyl prolyl cis-trans isomerase domain of human Pin1 with sulfate ion
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Xu, N, Tamari, Y, Tochio, N, Tate, S.
Deposit date:2014-03-25
Release date:2014-12-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.
Biochemistry, 53, 2014
2RUQ
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BU of 2ruq by Molmil
solution structure of human Pin1 PPIase mutant C113A
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Jing, W, Tochio, N, Tate, S.
Deposit date:2015-01-20
Release date:2016-01-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric Breakage of the Hydrogen Bond within the Dual-Histidine Motif in the Active Site of Human Pin1 PPIase
Biochemistry, 54, 2015
2RUD
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BU of 2rud by Molmil
Solution structure of the peptidyl prolyl cis-trans isomerase domain of C113D mutant human Pin1 with sulfate ion
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Xu, N, Tamari, Y, Tochio, N, Tate, S.
Deposit date:2014-03-25
Release date:2014-12-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.
Biochemistry, 53, 2014
2RUR
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BU of 2rur by Molmil
Solution structure of Human Pin1 PPIase C113S mutant
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Jing, W, Tochio, N, Tate, S.
Deposit date:2015-01-20
Release date:2016-01-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric Breakage of the Hydrogen Bond within the Dual-Histidine Motif in the Active Site of Human Pin1 PPIase
Biochemistry, 54, 2015
3GPK
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BU of 3gpk by Molmil
Crystal Structure of PpiC-type peptidyl-prolyl cis-trans isomerase domain at 1.55A resolution.
Descriptor: PpiC-type peptidyl-prolyl cis-trans isomerase, SULFATE ION
Authors:Satyanarayana, L, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-03-23
Release date:2009-03-31
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of PpiC-type peptidyl-prolyl cis-trans isomerase domain at 1.55A resolution.
To be Published
3I6C
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BU of 3i6c by Molmil
Structure-Based Design of Novel PIN1 Inhibitors (II)
Descriptor: 3-fluoro-N-(naphthalen-2-ylcarbonyl)-D-phenylalanine, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Greasley, S.E, Ferre, R.A.
Deposit date:2009-07-06
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-based design of novel human Pin1 inhibitors (II).
Bioorg.Med.Chem.Lett., 20, 2010
3IKD
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BU of 3ikd by Molmil
Structure-Based Design of Novel PIN1 Inhibitors (I)
Descriptor: (2R)-2-[(1-benzothiophen-2-ylcarbonyl)amino]-3-phenylpropyl phosphate, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Matthews, D, Greasley, S, Ferre, R, Parge, H.
Deposit date:2009-08-05
Release date:2009-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of novel human Pin1 inhibitors (I).
Bioorg.Med.Chem.Lett., 19, 2009

 

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