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8CA3
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BU of 8ca3 by Molmil
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-01-24
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8CA5
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BU of 8ca5 by Molmil
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-01-24
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8C2S
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BU of 8c2s by Molmil
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2022-12-22
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
8OLT
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BU of 8olt by Molmil
Mitochondrial complex I from Mus musculus in the active state bound with piericidin A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-03-30
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
8OM1
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BU of 8om1 by Molmil
Mitochondrial complex I from Mus musculus in the active state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-03-31
Release date:2023-08-09
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
8GYM
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BU of 8gym by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-23
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8GZU
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BU of 8gzu by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-27
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8BQ6
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BU of 8bq6 by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition)
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8B6F
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BU of 8b6f by Molmil
Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8ESW
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BU of 8esw by Molmil
Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Padavannil, A, Letts, J.A.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8ESZ
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BU of 8esz by Molmil
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
Descriptor: (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Padavannil, A, Letts, J.A.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8BQ5
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BU of 8bq5 by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition)
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
7W0Y
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BU of 7w0y by Molmil
Active state CI from Q10-NADH dataset, Subclass 2
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Gu, J.K, Yang, M.J.
Deposit date:2021-11-18
Release date:2023-03-22
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7R41
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BU of 7r41 by Molmil
Bovine complex I in the presence of IM1761092, active class i (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R47
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BU of 7r47 by Molmil
Bovine complex I in the presence of IM1761092, deactive class iii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R42
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BU of 7r42 by Molmil
Bovine complex I in the presence of IM1761092, active class ii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R43
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BU of 7r43 by Molmil
Bovine complex I in the presence of IM1761092, active class iii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R48
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BU of 7r48 by Molmil
Bovine complex I in the presence of IM1761092, deactive class iv (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R4C
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BU of 7r4c by Molmil
Bovine complex I in the presence of IM1761092, deactive class v (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R45
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BU of 7r45 by Molmil
Bovine complex I in the presence of IM1761092, deactive class i (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R4G
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BU of 7r4g by Molmil
Bovine complex I in the presence of IM1761092, slack class ii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R4F
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BU of 7r4f by Molmil
Bovine complex I in the presence of IM1761092, slack class i (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R46
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BU of 7r46 by Molmil
Bovine complex I in the presence of IM1761092, deactive class ii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R44
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BU of 7r44 by Molmil
Bovine complex I in the presence of IM1761092, active class iv (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023

217705

数据于2024-03-27公开中

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