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5O2L
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BU of 5o2l by Molmil
Myosin VI motor domain in the Pre-Transition State
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
Authors:Isabet, T, Benisty, H, Houdusse, A.
Deposit date:2017-05-22
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DUE
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BU of 6due by Molmil
Toxoplasma gondii MyoA, a Class-XIV myosin, in the pre-powerstroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Powell, C.J, Boulanger, M.J.
Deposit date:2018-06-20
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA fromToxoplasma gondii.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4ZG4
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BU of 4zg4 by Molmil
Myosin Vc Pre-powerstroke
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A.
Deposit date:2015-04-22
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Force-producing ADP state of myosin bound to actin.
Proc.Natl.Acad.Sci.USA, 113, 2016
6I7D
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BU of 6i7d by Molmil
Plasmodium falciparum Myosin A, post-rigor and rigor-like states
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Myosin-A
Authors:Robert-Paganin, J, Auguin, D, Moussaoui, D, Jousset, G, Baum, J, Trybus, K.M, Houdusse, A.
Deposit date:2018-11-16
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism.
Nat Commun, 10, 2019
6I7E
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BU of 6i7e by Molmil
Plasmodium falciparum Myosin A, Pre-powerstroke
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-A, ...
Authors:Robert-Paganin, J, Auguin, D, Moussaoui, D, Jousset, G, Baum, J, Trybus, K.M, Houdusse, A.
Deposit date:2018-11-16
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.492 Å)
Cite:Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism.
Nat Commun, 10, 2019
5HMP
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BU of 5hmp by Molmil
Myosin Vc pre-powerstroke state
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ...
Authors:Ropars, V, Pylypenko, O, Sweeney, H.L, Houdusse, A.
Deposit date:2016-01-16
Release date:2016-09-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:The myosin X motor is optimized for movement on actin bundles.
Nat Commun, 7, 2016
1W8J
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BU of 1w8j by Molmil
Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free
Descriptor: MYOSIN VA, SULFATE ION
Authors:Coureux, P.-D, Sweeney, H.L, Houdusse, A.
Deposit date:2004-09-22
Release date:2005-02-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction
Embo J., 23, 2004
4DBR
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BU of 4dbr by Molmil
Myosin VI D179Y (MD) pre-powerstroke state
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Pylypenko, O, Sweeney, H.L, Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
4PK4
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BU of 4pk4 by Molmil
Myosin VI motor domain in the PPS state - from a Pi release state crystal, space group P212121 after long soaking with PO4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-05-13
Release date:2015-04-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
4E7Z
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BU of 4e7z by Molmil
Myosin VI (MD) pre-powerstroke state, P21 crystal form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Isabet, T, Sweeney, H.L, Houdusse, A.
Deposit date:2012-03-19
Release date:2012-09-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI.
Mol.Cell, 48, 2012
4E7S
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BU of 4e7s by Molmil
Myosin VI D23R I24R R569E (MD) pre-powerstroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Isabet, T, Sweeney, H.L, Houdusse, A.
Deposit date:2012-03-19
Release date:2012-09-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI.
Mol.Cell, 48, 2012
4PFO
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BU of 4pfo by Molmil
Myosin VI motor domain in the Pi release state, space group P212121
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-04-30
Release date:2015-04-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
4PJM
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BU of 4pjm by Molmil
Myosin VI motor domain in the Pi release state, space group P212121 - soaked with PO4 - located in the active site
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-05-12
Release date:2015-04-29
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
4PFP
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BU of 4pfp by Molmil
Myosin VI motor domain in the Pi release state (with Pi) space group P21
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-04-30
Release date:2015-04-29
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
4PJN
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BU of 4pjn by Molmil
Myosin VI motor domain in the Pi release state, space group P212121 - shortly soaked with PO4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-05-12
Release date:2015-04-29
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
4PJL
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BU of 4pjl by Molmil
Myosin VI motor domain A458E mutant in the Pi release state, space group P212121 -
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A.
Deposit date:2014-05-12
Release date:2015-04-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How actin initiates the motor activity of Myosin.
Dev.Cell, 33, 2015
2V26
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BU of 2v26 by Molmil
Myosin VI (MD) pre-powerstroke state (Mg.ADP.VO4)
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Menetrey, J, Llinas, P, Mukherjea, M, Sweeney, H.L, Houdusse, A.
Deposit date:2007-06-03
Release date:2007-11-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Structural Basis for the Large Powerstroke of Myosin Vi.
Cell(Cambridge,Mass.), 131, 2007
1LKX
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BU of 1lkx by Molmil
MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN IE HEAVY CHAIN, ...
Authors:Kollmar, M, Durrwang, U, Kliche, W, Manstein, D.J, Kull, F.J.
Deposit date:2002-04-26
Release date:2002-06-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the motor domain of a class-I myosin.
EMBO J., 21, 2002
1BR4
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BU of 1br4 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-27
Release date:1998-09-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1B7T
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BU of 1b7t by Molmil
MYOSIN DIGESTED BY PAPAIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Houdusse, A, Kalabokis, V, Himmel, D, Szent-Gyorgyi, A.G, Cohen, C.
Deposit date:1999-01-15
Release date:1999-05-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
Cell(Cambridge,Mass.), 97, 1999
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Meinhart, A, Clausen, T, Arnese, R.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.884 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
7YV9
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BU of 7yv9 by Molmil
Cryo-EM structure of full-length Myosin Va in the autoinhibited state
Descriptor: Calmodulin-1, Unconventional myosin-Va
Authors:Niu, F, Wei, Z.
Deposit date:2022-08-19
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (4.78 Å)
Cite:Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va.
Sci Adv, 8, 2022
6UI4
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BU of 6ui4 by Molmil
Crystal structure of phenamacril-bound F. graminearum myosin I
Descriptor: Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F.
Deposit date:2019-09-30
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of Fusarium myosin I inhibition by phenamacril.
Plos Pathog., 16, 2020
4ZLK
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BU of 4zlk by Molmil
Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin
Descriptor: CALCIUM ION, Calmodulin, Unconventional myosin-Va
Authors:Shen, M, Zhang, N, Zheng, S, Zhang, W.-B, Zhang, H.-M, Lu, Z, Su, Q.P, Sun, Y, Ye, K, Li, X.-D.
Deposit date:2015-05-01
Release date:2016-05-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structural basis for calcium regulation of myosin 5 motor function
To Be Published
2JHR
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BU of 2jhr by Molmil
Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and pentabromopseudilin
Descriptor: ADP METAVANADATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN, ...
Authors:Fedorov, R, Boehl, M, Tsiavaliaris, G, Hartmann, F.K, Baruch, P, Brenner, B, Martin, R, Knoelker, H.J, Gutzeit, H.O, Manstein, D.J.
Deposit date:2008-03-25
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Mechanism of Pentabromopseudilin Inhibition of Myosin Motor Activity.
Nat.Struct.Mol.Biol., 16, 2009

217705

数据于2024-03-27公开中

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