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8GYM
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BU of 8gym by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-23
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8GZU
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BU of 8gzu by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-27
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8B6J
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BU of 8b6j by Molmil
Cryo-EM structure of cytochrome bc1 complex (complex-III) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apocytochrome b, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
7TGH
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BU of 7tgh by Molmil
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A.
Deposit date:2022-01-07
Release date:2022-04-06
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
3L73
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BU of 3l73 by Molmil
Cytochrome BC1 complex from chicken with triazolone inhibitor
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 4-[7-(3,3-dimethylbut-1-yn-1-yl)naphthalen-1-yl]-5-methoxy-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one, CARDIOLIPIN, ...
Authors:Huang, L, Berry, E.A.
Deposit date:2009-12-27
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the Qo site of the BC1 compl and fix the rieske iron-sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "DISTAL" Qo inhibitors.
To be Published
7TZ6
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BU of 7tz6 by Molmil
Structure of mitochondrial bc1 in complex with ck-2-68
Descriptor: 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Xia, D, Esser, L, Zhou, F, Huang, R.
Deposit date:2022-02-15
Release date:2023-02-22
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
J.Biol.Chem., 299, 2023
1BGY
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BU of 1bgy by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-06-02
Release date:1999-01-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
3TGU
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BU of 3tgu by Molmil
Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ...
Authors:Huang, L.-S, Yang, G.-F, Berry, E.A.
Deposit date:2011-08-17
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.
J.Am.Chem.Soc., 134, 2012
4U3F
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BU of 4u3f by Molmil
Cytochrome bc1 complex from chicken with designed inhibitor bound
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CARDIOLIPIN, ...
Authors:Huang, L.-S, Zhu, X.-L, Yang, G.F, Berry, E.A.
Deposit date:2014-07-21
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2312 Å)
Cite:Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization
Sci Rep, 5, 2015
1EZV
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BU of 1ezv by Molmil
STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT
Descriptor: 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CYTOCHROME B, CYTOCHROME C1, ...
Authors:Hunte, C, Koepke, J, Lange, C, Rossmanith, T, Michel, H.
Deposit date:2000-05-12
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Structure Fold.Des., 8, 2000
6FO6
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BU of 6fo6 by Molmil
CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911
Descriptor: 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy)phenyl]pyridin-3-yl]quinolin-4-ol, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Johnson, R.M, Amporndanai, K, O'Neill, P.M, Fishwick, C.W.G, Jamson, A.H, Rawson, S.D, Hasnain, S.S, Antonyuk, S.V, Muench, S.P.
Deposit date:2018-02-06
Release date:2018-02-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
5NMI
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BU of 5nmi by Molmil
Cytochrome bc1 bound to the inhibitor MJM170
Descriptor: (4aS)-2-methyl-3-(4-phenoxyphenyl)-5,6,7,8-tetrahydroquinolin-4(4aH)-one, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ARG-ASN-TRP-VAL-PRO-THR-ALA-GLN-LEU-TRP-GLY-ALA-VAL-GLY-ALA-VAL-GLY-LEU-VAL-SER-ALA-THR, ...
Authors:Capper, N.J, Antonyuk, S.V, Hasnain, S.S.
Deposit date:2017-04-05
Release date:2017-06-14
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Sci Rep, 6, 2016
1BCC
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BU of 1bcc by Molmil
CYTOCHROME BC1 COMPLEX FROM CHICKEN
Descriptor: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H.
Deposit date:1998-03-23
Release date:1998-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Electron transfer by domain movement in cytochrome bc1.
Nature, 392, 1998
1BE3
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BU of 1be3 by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-05-19
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
6T0B
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BU of 6t0b by Molmil
The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-02
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
8SNH
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BU of 8snh by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-27
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023
6T15
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BU of 6t15 by Molmil
The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CARDIOLIPIN, COPPER (II) ION, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-03
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
8SMR
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BU of 8smr by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-26
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023
5OKD
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BU of 5okd by Molmil
Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911.
Descriptor: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
Authors:Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V.
Deposit date:2017-07-25
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
8EC0
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BU of 8ec0 by Molmil
III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ...
Authors:Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W.
Deposit date:2022-08-31
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex.
Nat Commun, 14, 2023
8E7S
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BU of 8e7s by Molmil
III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6
Descriptor: (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ...
Authors:Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W.
Deposit date:2022-08-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex.
Nat Commun, 14, 2023
4D6U
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BU of 4d6u by Molmil
Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 3-chloro-6-(hydroxymethyl)-2-methyl-5-{4-[3-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol, CARDIOLIPIN, ...
Authors:Capper, M.J, ONeill, P.M, Fisher, N, Strange, R.W, Moss, D, Ward, S.A, Berry, N.G, Lawrenson, A.S, Hasnain, S.S, Biagini, G.A, Antonyuk, S.V.
Deposit date:2014-11-14
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.09 Å)
Cite:Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1.
Proc.Natl.Acad.Sci.USA, 112, 2015
4D6T
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BU of 4d6t by Molmil
Cytochrome bc1 bound to the 4(1H)-pyridone GW844520
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 3-chloro-2,6-dimethyl-5-{4-[4-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol, CARDIOLIPIN, ...
Authors:Capper, M.J, O'Neill, P.M, Fisher, N, Strange, R.W, Moss, D, Ward, S.A, Berry, N.G, Lawrenson, A.S, Hasnain, S.S, Biagini, G.A, Antonyuk, S.V.
Deposit date:2014-11-14
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1.
Proc.Natl.Acad.Sci.USA, 112, 2015
1SQV
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BU of 1sqv by Molmil
Crystal Structure Analysis of Bovine Bc1 with UHDBT
Descriptor: 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE, Cytochrome b, Cytochrome c1, ...
Authors:Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D.
Deposit date:2004-03-19
Release date:2005-09-06
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004

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数据于2024-03-27公开中

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