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3TGX
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BU of 3tgx by Molmil
IL-21:IL21R complex
Descriptor: Interleukin-21, Interleukin-21 receptor, NICKEL (II) ION, ...
Authors:Hamming, O.J, Kang, L, Svenson, A, Karlsen, J.L, Rahbek-Nielsen, H, Paludan, S.R, Hjort, S.A, Bondensgaard, K, Hartmann, R.
Deposit date:2011-08-18
Release date:2012-02-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor.
J.Biol.Chem., 2012
2OQP
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BU of 2oqp by Molmil
Solution structure of human interleukin-21
Descriptor: Interleukin-21
Authors:Bondensgaard, K, Breinholt, J.
Deposit date:2007-02-01
Release date:2007-06-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogue.
J.Biol.Chem., 282, 2007
2XQB
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BU of 2xqb by Molmil
Crystal Structure of anti-IL-15 Antibody in Complex with human IL-15
Descriptor: ANTI-IL-15 ANTIBODY, INTERLEUKIN 15, SULFATE ION
Authors:Lowe, D.C, Gerhardt, S, Ward, A, Hargreaves, D, Anderson, M, StGallay, S, Vousden, K, Ferraro, F, Pauptit, R.A, Cochrane, D, Pattison, D.V, Buchanan, C, Popovic, B, Finch, D.K, Wilkinson, T, Sleeman, M, Vaughan, T.J, Cruwys, S, Mallinder, P.R.
Deposit date:2010-09-01
Release date:2010-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope.
J.Mol.Biol., 406, 2011
2Z3Q
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Crystal structure of the IL-15/IL-15Ra complex
Descriptor: Interleukin-15, Interleukin-15 receptor alpha chain
Authors:Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
2Z3R
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BU of 2z3r by Molmil
Crystal structure of the IL-15/IL-15Ra complex
Descriptor: GLYCEROL, Interleukin-15, Interleukin-15 receptor alpha chain
Authors:Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
8ENT
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BU of 8ent by Molmil
Interleukin-21 signaling complex with IL-21R and IL-2Rg
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Abhiraman, G.C, Jude, K.M, Garcia, K.C.
Deposit date:2022-09-30
Release date:2023-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:A structural blueprint for interleukin-21 signal modulation.
Cell Rep, 42, 2023
4GS7
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BU of 4gs7 by Molmil
Structure of the Interleukin-15 quaternary complex
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ring, A.M, Ozkan, E, Feng, D, Garcia, K.C.
Deposit date:2012-08-27
Release date:2012-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.
Nat.Immunol., 13, 2012
2PSM
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BU of 2psm by Molmil
Crystal structure of Interleukin 15 in complex with Interleukin 15 receptor alpha
Descriptor: BENZAMIDINE, Interleukin-15, Interleukin-15 receptor alpha chain
Authors:Olsen, S.K, Murayama, K, Kishishita, S, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Ota, N, Kanagawa, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2007-11-06
Last modified:2021-08-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of the Interleukin-15{middle dot}Interleukin-15 Receptor {alpha} Complex: INSIGHTS INTO TRANS AND CIS PRESENTATION
J.Biol.Chem., 282, 2007

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