8QQ3
| Streptavidin with a Ni-cofactor | Descriptor: | 4-[4-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butylamino]-~{N}1,~{N}1'-di(quinolin-8-yl)cyclohexane-1,1-dicarboxamide, NICKEL (II) ION, Streptavidin | Authors: | Zhang, K, Jakob, R.P, Ward, T.R. | Deposit date: | 2023-10-03 | Release date: | 2024-02-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An artificial nickel chlorinase based on the biotin-streptavidin technology. Chem.Commun.(Camb.), 60, 2024
|
|
1DF8
| S45A MUTANT OF STREPTAVIDIN IN COMPLEX WITH BIOTIN | Descriptor: | BIOTIN, PROTEIN (STREPTAVIDIN) | Authors: | Hyre, D.E, Le Trong, I, Freitag, S, Stenkamp, R.E, Stayton, P.S. | Deposit date: | 1999-11-18 | Release date: | 2000-09-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Ser45 plays an important role in managing both the equilibrium and transition state energetics of the streptavidin-biotin system. Protein Sci., 9, 2000
|
|
4U46
| Crystal structure of an avidin mutant | Descriptor: | Avidin, CHLORIDE ION | Authors: | Agrawal, N, Lehtonen, S, Kahkonen, N, Riihimaki, T, Hytonen, V.P, Kulomaa, M.S, Johnson, M.S, Airenne, T.T. | Deposit date: | 2014-07-23 | Release date: | 2015-08-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Artificial Avidin-Based Receptors for a Panel of Small Molecules. Acs Chem.Biol., 11, 2016
|
|
8GVK
| |
4OKA
| Structural-, Kinetic- and Docking Studies of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis | Descriptor: | IRIDIUM ION, Streptavidin, [N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamidato]iridium(III) | Authors: | Schirmer, T, Heinisch, T. | Deposit date: | 2014-01-22 | Release date: | 2014-11-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.505 Å) | Cite: | Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis J.Am.Chem.Soc., 136, 2014
|
|
7ZOF
| Streptavidin Iron-Porphyrin | Descriptor: | (2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-[[(5Z,10Z,14Z,19Z)-15-[[[(2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-sulfo-propanoyl]amino]methyl]-1,4,21,23-tetrahydroporphyrin-5-yl]methylamino]-3-oxidanylidene-propane-1-sulfonic acid, FE (III) ION, IMIDAZOLE, ... | Authors: | Igareta, N.V, Ward, T.R. | Deposit date: | 2022-04-25 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Streptavidin Iron-Porphyrin To Be Published
|
|
1AVD
| THREE-DIMENSIONAL STRUCTURE OF THE TETRAGONAL CRYSTAL FORM OF EGG-WHITE AVIDIN IN ITS FUNCTIONAL COMPLEX WITH BIOTIN AT 2.7 ANGSTROMS RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AVIDIN, BIOTIN | Authors: | Pugliese, L, Coda, A, Malcovati, M, Bolognesi, M. | Deposit date: | 1993-03-05 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 A resolution. J.Mol.Biol., 231, 1993
|
|
1AVE
| CRYSTAL STRUCTURE OF HEN EGG-WHITE APO-AVIDIN IN RELATION TO ITS THERMAL STABILITY PROPERTIES | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AVIDIN | Authors: | Pugliese, L, Coda, A, Malcovati, M, Bolognesi, M. | Deposit date: | 1993-03-05 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of apo-avidin from hen egg-white. J.Mol.Biol., 235, 1994
|
|
7ALX
| Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes | Descriptor: | ((4S)-1,3-dimesityl-4-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)imidazolidin-2-yl)gold, Streptavidin,Superoxide dismutase [Cu-Zn],Streptavidin | Authors: | Igareta, N.V, Christoffel, F, Peterson, R.L, Ward, T.R. | Deposit date: | 2020-10-07 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis Nat Catal, 4, 2021
|
|
7B74
| Chimeric Streptavidin With A Dimerization Domain For Artificial Transfer Hydrogenation | Descriptor: | Streptavidin,Superoxide dismutase [Cu-Zn],Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) | Authors: | Igareta, N.V, Ward, T.R. | Deposit date: | 2020-12-09 | Release date: | 2021-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Spiers Memorial Lecture: Shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation. Faraday Disc.Chem.Soc, 2023
|
|
6LNG
| Rapid crystallization of streptavidin using charged peptides | Descriptor: | GLYCEROL, Streptavidin | Authors: | Minamihata, K, Tsukamoto, K, Adachi, M, Shimizu, R, Mishina, M, Kuroki, R, Nagamune, T. | Deposit date: | 2019-12-30 | Release date: | 2020-03-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8000015 Å) | Cite: | Genetically fused charged peptides induce rapid crystallization of proteins. Chem.Commun.(Camb.), 56, 2020
|
|
6M9B
| |
7ZN1
| Avidin + Biotin-Tempo | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)hexanamide, ... | Authors: | Milani, J, Lau, K, Pojer, F, Ansermet, J.P, Saenz, F. | Deposit date: | 2022-04-20 | Release date: | 2023-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Avidin + Biotin-Tempo To Be Published
|
|
7ZXZ
| dithiol-ligand bound to streptavidin | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(1~{R},3~{S})-3-[3,5-bis(sulfanylmethyl)phenyl]-2,4-bis(oxidanylidene)cyclopentyl]pentanamide, DI(HYDROXYETHYL)ETHER, Streptavidin | Authors: | Igareta, N.V, Ward, T.R. | Deposit date: | 2022-05-23 | Release date: | 2022-06-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | dithiol-ligand bound to streptavidin To Be Published
|
|
7ZX9
| Streptavidin with a fluorescent substrate | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[6-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-1,3-bis(oxidanylidene)benzo[de]isoquinolin-2-yl]ethyl]pentanamide, Streptavidin | Authors: | Igareta, N.V, Ward, T.R. | Deposit date: | 2022-05-20 | Release date: | 2022-06-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.546 Å) | Cite: | Streptavidin Iron-Porphyrin To Be Published
|
|
3EW2
| Crystal structure of rhizavidin-biotin complex | Descriptor: | BIOTIN, rhizavidin | Authors: | Livnah, O, Meir, A. | Deposit date: | 2008-10-14 | Release date: | 2008-12-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. J.Mol.Biol., 386, 2009
|
|
3EW1
| Crystal structure of rhizavidin | Descriptor: | rhizavidin | Authors: | Livnah, O, Meir, A. | Deposit date: | 2008-10-14 | Release date: | 2008-12-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. J.Mol.Biol., 386, 2009
|
|
3FDC
| Crystal Structure of Avidin | Descriptor: | Avidin, iron(II) tetracyano-5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid (4'-methyl-[2,2']bipyridinyl-4-ylmethyl)-amide | Authors: | Barker, K.D, Sazinsky, M.H, Eckermann, A.L, Abajian, C, Hartings, M.R, Rosenzweig, A.C, Meade, T.J. | Deposit date: | 2008-11-25 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Protein Binding and the Electronic Properties of Iron(II) Complexes: An Electrochemical and Optical Investigation of Outer Sphere Effects. Bioconjug.Chem., 20, 2009
|
|
6ESS
| Artificial imine reductase mutant S112A-N118P-K121A-S122M | Descriptor: | IRIDIUM ION, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) | Authors: | Hestericova, M, Heinisch, T, Alonso-Cotchico, L, Marechal, J.-D, Vidossich, P, Ward, T.R. | Deposit date: | 2017-10-24 | Release date: | 2018-01-03 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Directed Evolution of an Artificial Imine Reductase. Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
6ESU
| Artificial imine reductase mutant S112A-N118P-K121A-S122M | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[4-(2-azanylethylsulfamoyl)phenyl]pentanamide, ACETATE ION, IRIDIUM ION, ... | Authors: | Hestericova, M, Heinisch, T, Alonso-Cotchico, L, Marechal, J.-D, Vidossich, P, Ward, T.R. | Deposit date: | 2017-10-24 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Directed Evolution of an Artificial Imine Reductase. Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
6FH8
| E. coli surface display of streptavidin for directed evolution of an allylic deallocase | Descriptor: | Streptavidin, biotinylated ruthenium cyclopentadienide | Authors: | Heinisch, T, Schwizer, F, Garabedian, B, Csibra, E, Jeschek, M, Pinheiro Bernhardes, V, Marliere, P, Panke, S, Ward, T.R. | Deposit date: | 2018-01-12 | Release date: | 2018-08-22 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | E. colisurface display of streptavidin for directed evolution of an allylic deallylase. Chem Sci, 9, 2018
|
|
6FRY
| Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology | Descriptor: | Streptavidin, [CoBr(appy)-Biot]Br | Authors: | Keller, S, Probst, B, Heinisch, T, Alberto, R, Ward, T.R. | Deposit date: | 2018-02-16 | Release date: | 2019-03-13 | Last modified: | 2020-11-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology Helv.Chim.Acta, 101, 2018
|
|
5B5F
| Crystal structure of ALiS3-Streptavidin complex | Descriptor: | N-methyl-3-(4-oxo-4,5-dihydrofuro[3,2-c]pyridin-2-yl)benzenesulfonamide, Streptavidin | Authors: | Sugiyama, S, Terai, T, Kakinouchi, K, Fujikake, R, Nagano, T, Urano, Y. | Deposit date: | 2016-05-04 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells Chembiochem, 18, 2017
|
|
5B5G
| Crystal structure of ALiS4-Streptavidin complex | Descriptor: | SULFITE ION, Streptavidin, methyl 5-(4-oxidanylidene-5~{H}-furo[3,2-c]pyridin-2-yl)pyridine-3-carboxylate | Authors: | Sugiyama, S, Terai, T, Kakinouchi, K, Fujikake, R, Nagano, T, Urano, Y. | Deposit date: | 2016-05-04 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells Chembiochem, 18, 2017
|
|
8GOG
| Structure of streptavidin mutant (S112Y-K121E) complexed with biotin-cyclopentadienyl-rhodium (III)(Cp*-Rh(III)) | Descriptor: | CHLORIDE ION, GLYCEROL, RHODIUM(III) ION, ... | Authors: | Sairaman, A, Mukherjee, P, Maiti, D, Bhaumik, P. | Deposit date: | 2022-08-24 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Artificial metalloenzyme catalyzed enantiodivergent synthesis of isoindolones To Be Published
|
|