4R8X
 
 | | Crystal structure of a uricase from Bacillus fastidious | | Descriptor: | Uricase | | Authors: | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | | Deposit date: | 2014-09-03 | | Release date: | 2015-05-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions.
Appl.Microbiol.Biotechnol., 99, 2015
|
|
1J2G
 | |
4FSK
 | | Urate oxidase-azide complex in anaerobic conditions | | Descriptor: | AZIDE ION, SODIUM ION, Uricase | | Authors: | Gabison, L, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M, Prange, T. | | Deposit date: | 2012-06-27 | | Release date: | 2013-07-03 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Azide and Cyanide Have Different Inhibition Modes of Urate Oxidase
To be Published
|
|
2PES
 | | Urate Oxidase in complex with tris-dipicolinate Lutetium | | Descriptor: | 8-AZAXANTHINE, LUTETIUM (III) ION, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | | Authors: | Pompidor, G, Vicat, J, Kahn, R. | | Deposit date: | 2007-04-03 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction.
Acta Crystallogr.,Sect.D, 66, 2010
|
|
6OE8
 | | The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C | | Descriptor: | MALONATE ION, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | Authors: | Shi, Y, Wang, T, Zhou, X.E, Liu, Q, Jiang, Y, Xu, H.E. | | Deposit date: | 2019-03-27 | | Release date: | 2019-08-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy.
Acta Pharmacol.Sin., 40, 2019
|
|
7A0L
 | | Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole | | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | | Authors: | McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A. | | Deposit date: | 2020-08-09 | | Release date: | 2020-12-09 | | Last modified: | 2021-02-10 | | Method: | NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION | | Cite: | Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis.
Iucrj, 8, 2021
|
|
5FRC
 | | Structure of urate oxidase prepared by the 'soak-and-freeze' method under 42 bar of oxygen pressure | | Descriptor: | 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ... | | Authors: | Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P. | | Deposit date: | 2015-12-16 | | Release date: | 2016-10-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.443 Å) | | Cite: | Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology.
J.Appl.Crystallogr., 49, 2016
|
|
3WLV
 | | Thermostable urate oxidase from Bacillus sp. TB-90 | | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Hibi, T, Hayashi, Y, Itoh, T. | | Deposit date: | 2013-11-14 | | Release date: | 2014-06-18 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (1.747 Å) | | Cite: | Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase.
Biochemistry, 53, 2014
|
|
2FUB
 | | Crystal structure of urate oxidase at 140 MPa | | Descriptor: | 8-AZAXANTHINE, CYSTEINE, Uricase | | Authors: | Colloc'h, N, Girard, E, Fourme, R. | | Deposit date: | 2006-01-26 | | Release date: | 2006-02-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | High pressure macromolecular crystallography: The 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly
Biochim.Biophys.Acta, 1764, 2006
|
|
4XFP
 | | Crystal Structure of Highly Active Mutant of Bacillus sp. TB-90 Urate Oxidase | | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, SULFATE ION, ... | | Authors: | Hibi, T, Hayashi, Y, Kawamura, A, Itoh, T. | | Deposit date: | 2014-12-28 | | Release date: | 2016-01-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Glycine Substitution of Surface Proline 287 Involves Entropic Enhancement of Bacillus sp. TB-90 Uricase Activity
To be published
|
|
7F2V
 | | Urate oxidase from Thermobispora bispora in apo form | | Descriptor: | DIMETHYL SULFOXIDE, SULFATE ION, Uricase | | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | | Deposit date: | 2021-06-14 | | Release date: | 2022-05-04 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy.
Int.J.Biol.Macromol., 188, 2021
|
|
7F2W
 | | TbUox in complex with uric acid | | Descriptor: | URIC ACID, Uricase | | Authors: | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | | Deposit date: | 2021-06-14 | | Release date: | 2022-05-04 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy.
Int.J.Biol.Macromol., 188, 2021
|
|
5LL1
 | |
6RGT
 | | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-METHYL URIC ACID, ... | | Authors: | Bui, S, Lowden, S.R.J, Steiner, R.A. | | Deposit date: | 2019-04-17 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid
To Be Published
|
|
6RGM
 | | urate oxidase under 130 bar of krypton | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ... | | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | | Deposit date: | 2019-04-17 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
|
|
5M98
 | |
5AYJ
 | | Hyperthermostable mutant of Bacillus sp. TB-90 Urate Oxidase - R298C | | Descriptor: | 9-METHYL URIC ACID, HEXAETHYLENE GLYCOL, SULFATE ION, ... | | Authors: | Hibi, T, Kume, A, Kawamura, A, Itoh, T, Nishiya, Y. | | Deposit date: | 2015-08-21 | | Release date: | 2016-01-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Hyperstabilization of Tetrameric Bacillus sp. TB-90 Urate Oxidase by Introducing Disulfide Bonds through Structural Plasticity
Biochemistry, 55, 2016
|
|
5Y52
 | |
5YJ2
 | |
5Y2P
 | |
2FXL
 | | Urate oxidase from aspergillus flavus complexed with allantoin | | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Uricase | | Authors: | Gabison, L, Chiadmi, M, Colloc'h, N, Prange, T. | | Deposit date: | 2006-02-06 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase.
Febs Lett., 580, 2006
|
|
5YJA
 | |
3BK8
 | | Urate oxidase aza-xanthine complex in cyanide | | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | | Authors: | Gabison, L, Prange, T, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M. | | Deposit date: | 2007-12-06 | | Release date: | 2008-08-12 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
Bmc Struct.Biol., 8, 2008
|
|
5Z2B
 | |
5Z27
 | |
