7P2B
 
 | |
5O2Z
 | | Domain swap dimer of the G167R variant of gelsolin second domain | | Descriptor: | ACETATE ION, CALCIUM ION, CITRATE ANION, ... | | Authors: | Boni, F, Milani, M, Mastrangelo, E, de Rosa, M. | | Deposit date: | 2017-05-23 | | Release date: | 2017-11-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein.
Hum. Mol. Genet., 27, 2018
|
|
6QW3
 | | Calcium-bound gelsolin domain 2 | | Descriptor: | CALCIUM ION, Gelsolin | | Authors: | Scalone, E, Boni, F, Milani, M, Mastrangelo, E, de Rosa, M. | | Deposit date: | 2019-03-05 | | Release date: | 2019-08-28 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.
Biochem.Biophys.Res.Commun., 518, 2019
|
|
4S10
 | |
5ZZ0
 | | HUMAN GELSOLIN FROM RESIDUES GLU28 TO ARG161 WITH CALCIUM | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, Gelsolin | | Authors: | Sharma, P, Badmalia, M, Yadav, S.P.S, Singh, S. | | Deposit date: | 2018-05-29 | | Release date: | 2019-06-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.635 Å) | | Cite: | Bonsai Gelsolin Survives Heat Induced Denaturation by Forming beta-Amyloids which Leach Out Functional Monomer.
Sci Rep, 8, 2018
|
|
5H3M
 | |
5H3N
 | |
5FAE
 | | N184K pathological variant of gelsolin domain 2 (trigonal form) | | Descriptor: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Boni, F, Milani, M, Ricagno, S, Bolognesi, M, de Rosa, M. | | Deposit date: | 2015-12-11 | | Release date: | 2016-10-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
|
|
6H1F
 | | Structure of the nanobody-stabilized gelsolin D187N variant (second domain) | | Descriptor: | Gelsolin, THIOCYANATE ION, gelsolin nanobody, ... | | Authors: | Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M. | | Deposit date: | 2018-07-11 | | Release date: | 2019-01-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
|
|
5FAF
 | | N184K pathological variant of gelsolin domain 2 (orthorhombic form) | | Descriptor: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Boni, F, Milani, M, Ricagno, s, Bolognesi, M, de Rosa, M. | | Deposit date: | 2015-12-11 | | Release date: | 2016-10-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
|
|
2VIK
 | |
2VIL
 | |
6Q9Z
 | | Crystal structure of the pathological G167R variant of calcium-free human gelsolin, | | Descriptor: | GLYCEROL, Gelsolin, SULFATE ION | | Authors: | Boni, F, Scalone, E, Milani, M, Eloise, M, de Rosa, M. | | Deposit date: | 2018-12-18 | | Release date: | 2019-11-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
|
|
6QBF
 | | Crystal structure of the pathological D187N variant of calcium-free human gelsolin. | | Descriptor: | GLYCEROL, Gelsolin, SODIUM ION, ... | | Authors: | Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M. | | Deposit date: | 2018-12-21 | | Release date: | 2019-11-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.499 Å) | | Cite: | The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
|
|
6Q9R
 | | Crystal structure of the pathological N184K variant of calcium-free human gelsolin | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M. | | Deposit date: | 2018-12-18 | | Release date: | 2019-11-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
|
|
5A1K
 | |
5A1M
 | | Crystal structure of calcium-bound human adseverin domain A3 | | Descriptor: | ADSEVERIN, CALCIUM ION | | Authors: | Chumnarnsilpa, S, Robinson, R.C, Grimes, J.M, Leyrat, C. | | Deposit date: | 2015-05-01 | | Release date: | 2015-09-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Calcium-Controlled Conformational Choreography in the N-Terminal Half of Adseverin.
Nat.Commun., 6, 2015
|
|
2LLF
 | | Sixth Gelsolin-like domain of villin in 5 mM CaCl2 | | Descriptor: | Villin-1 | | Authors: | Pfaff, D.A, Brockerman, J, Fedechkin, S, Burns, L, Zhang, F, Mcknight, C, Smirnov, S.L. | | Deposit date: | 2011-11-07 | | Release date: | 2012-11-07 | | Last modified: | 2015-04-15 | | Method: | SOLUTION NMR | | Cite: | Gelsolin-like activation of villin: calcium sensitivity of the long helix in domain 6.
Biochemistry, 52, 2013
|
|
1SVQ
 | |
1SVY
 | | SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE | | Descriptor: | CALCIUM ION, SEVERIN, SODIUM ION | | Authors: | Puius, Y.A, Fedorov, E.V, Eichinger, L, Sullivan, M, Schleicher, M, Almo, S.C. | | Deposit date: | 1998-08-10 | | Release date: | 1999-08-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry, 39, 2000
|
|
1D0N
 | | THE CRYSTAL STRUCTURE OF CALCIUM-FREE EQUINE PLASMA GELSOLIN. | | Descriptor: | HORSE PLASMA GELSOLIN | | Authors: | Burtnick, L.D, Robinson, R, Li, C. | | Deposit date: | 1999-09-13 | | Release date: | 1999-09-15 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation.
Cell(Cambridge,Mass.), 90, 1997
|
|
1SVR
 | |
2FH3
 | | C-terminal half of gelsolin soaked in low calcium at pH 8 | | Descriptor: | CALCIUM ION, Gelsolin | | Authors: | Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. | | Deposit date: | 2005-12-23 | | Release date: | 2006-06-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
|
|
2FGH
 | | ATP bound gelsolin | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, gelsolin | | Authors: | Ma, Q, Robinson, R.C, Burtnick, L.D, Urosev, D. | | Deposit date: | 2005-12-22 | | Release date: | 2006-04-18 | | Last modified: | 2017-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structure of gelsolin bound to ATP
J.Mol.Biol., 357, 2006
|
|
2FH2
 | | C-terminal half of gelsolin soaked in EGTA at pH 4.5 | | Descriptor: | CALCIUM ION, Gelsolin | | Authors: | Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. | | Deposit date: | 2005-12-23 | | Release date: | 2006-06-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
|
|
