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6NJ7	11-BETA DEHYDROGENASE ISOZYME 1 IN COMPLEX WITH COLLETOIC ACID Descriptor: (1S,4S,5S,9S)-9-hydroxy-8-methyl-4-(propan-2-yl)spiro[4.5]dec-7-ene-1-carboxylic acid, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Miller, D.J, Rivas, F. Deposit date: 2019-01-02 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Mechanistic Insight on the Mode of Action of Colletoic Acid. J.Med.Chem., 62, 2019
7ULH	Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 Descriptor: Short chain dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-04-04 Release date: 2022-04-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 to be published
4RZH	Crystal structure of FabG from Synechocystis sp. PCC 6803 Descriptor: 3-oxoacyl-[acyl-carrier protein] reductase Authors: Liu, Y, Xue, S. Deposit date: 2014-12-22 Release date: 2015-09-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803. Febs Lett., 589, 2015
4WEO	Crystal Structure of a Putative acetoin(Diacetyl) Reductase Burkholderia cenocepacia Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-09-10 Release date: 2014-09-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of a Putative acetoin(Diacetyl) Reductase Burkholderia cenocepacia to be published
4TRR	Crystal structure of a putative Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 Descriptor: 1,2-ETHANEDIOL, Putative D-beta-hydroxybutyrate dehydrogenase, SULFATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-06-17 Release date: 2014-08-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a putative Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 to be published
1CYD	CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL Descriptor: CARBONYL REDUCTASE, ISOPROPYL ALCOHOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Tanaka, N, Nonaka, T, Mitsui, Y. Deposit date: 1995-09-01 Release date: 1996-10-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure, 4, 1996
1DHR	CRYSTAL STRUCTURE OF RAT LIVER DIHYDROPTERIDINE REDUCTASE Descriptor: DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Varughese, K.I, Skinner, M.M, Whiteley, J.M, Matthews, D.A, Xuong, N.H. Deposit date: 1992-03-30 Release date: 1993-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of rat liver dihydropteridine reductase. Proc.Natl.Acad.Sci.USA, 89, 1992
4XGN	Crystal structure of 3-hydroxyacyl-CoA dehydrogenase in complex with NAD from Burkholderia thailandensis Descriptor: 1,2-ETHANEDIOL, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-12-31 Release date: 2015-01-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of 3-hydroxyacyl-CoA dehydrogenase in complex with NAD from Burkholderia thailandensis to be published
7N09	Structural basis for branched substrate selectivity in a ketoreductase from Ascaris suum Descriptor: 3-hydroxyacyl-CoA dehydrogenase type-2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Dong, H, Chang, M.C.Y. Deposit date: 2021-05-25 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis for Branched Substrate Selectivity in a Ketoreductase from Ascaris suum Acs Catalysis, 11, 2021
5FYD	Structural and biochemical insights into 7beta-hydroxysteroid dehydrogenase stereoselectivity Descriptor: GLYCEROL, OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY PROTEIN Authors: Savino, S, Ferrandi, E, Forneris, F, Rovida, S, Riva, S, Monti, D, Mattevi, A. Deposit date: 2016-03-07 Release date: 2016-04-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural and Biochemical Insights Into 7Beta-Hydroxysteroid Dehydrogenase Stereoselectivity. Proteins, 84, 2016
5GT9	The X-ray structure of 7beta-hydroxysteroid dehydrogenase Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein Authors: Wang, F, Wang, R, Lv, Z, Chen, Q, Huo, X. Deposit date: 2016-08-19 Release date: 2017-05-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes Acta Crystallogr F Struct Biol Commun, 73, 2017
6UHX	Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized oxidoreductase YIR035C Authors: Stogios, P.J, Skarina, T, Chen, C, Kagan, O, Iakounine, A, Savchenko, A. Deposit date: 2019-09-29 Release date: 2020-08-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae To Be Published
6UJK	Crystal Structure of a Probable short-chain type dehydrogenase/reductase (Rv1144) from Mycobacterium tuberculosis with bound NAD Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-10-03 Release date: 2019-10-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal Structure of a Probable short-chain type dehydrogenase/reductase (Rv1144) from Mycobacterium tuberculosis with bound NAD to be published
6USN	Co-crystal structure of SPR with compound 5 Descriptor: (2-hydroxyphenyl)[3-methyl-1-(pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Huang, X, Wang, K. Deposit date: 2019-10-28 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.773 Å) Cite: Virtual screening to identify potent sepiapterin reductase inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
7X3Z	Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NAD Descriptor: (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, 17-beta-hydroxysteroid dehydrogenase type 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Li, T, Lin, S.X, Yin, H. Deposit date: 2022-03-01 Release date: 2023-01-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: New insights into the substrate inhibition of human 17 beta-hydroxysteroid dehydrogenase type 1. J.Steroid Biochem.Mol.Biol., 228, 2023
7JK9	Helical filaments of plant light-dependent protochlorophyllide oxidoreductase (LPOR) bound to NADPH, Pchlide, and membrane Descriptor: 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protochlorophyllide, ... Authors: Nguyen, H.C, Gabruk, M, Frost, A. Deposit date: 2020-07-28 Release date: 2021-03-17 Last modified: 2021-10-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. Nat.Plants, 7, 2021
7X5J	ACP-dependent oxoacyl reductase Descriptor: 3-oxoacyl-ACP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHENYLALANINE Authors: Wang, S, Bai, L. Deposit date: 2022-03-04 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: ACP-dependent oxoacyl reductase To Be Published
7LG9	ChsB1 Descriptor: 3-ketoacyl-ACP reductase Authors: Yuan, T, Werman, J.M, Yin, X, Yang, M, Garcia-Diaz, M, Sampson, N.S. Deposit date: 2021-01-19 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Enzymatic beta-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infect Dis., 7, 2021
7LGB	ChsB1 in complex with NAD+ Descriptor: 3-ketoacyl-ACP reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Yuan, T, Werman, J.M, Yin, X, Yang, M, Garcia-Diaz, M, Sampson, N.S. Deposit date: 2021-01-19 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Enzymatic beta-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infect Dis., 7, 2021
7YPD	Discovery and characterization of a new carbonyl reductase from Rhodotorula toluroides reducing fluoroketones, and X-ray analysis of the variant by rational engineering Descriptor: Carbonyl reductase, MAGNESIUM ION Authors: Watanabe, Y, Asano, Y, Hibi, M. Deposit date: 2022-08-03 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Discovery and characterization of a new carbonyl reductase from Rhodotorula toluroides reducing fluoroketones, and X-ray analysis of the variant by rational engineering To Be Published
6R48	Crystal structure of LPOR (Synechocystis) complexed with NADPH at 1.87A resolution. Descriptor: CHLORIDE ION, Light-dependent protochlorophyllide reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Zhou, A, Feng, L. Deposit date: 2019-03-22 Release date: 2019-10-30 Last modified: 2020-05-13 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6R46	Crystal structure of LPOR (Thermosynechococcus elongatus) complexed with NADP+ at 2.5A resolution Descriptor: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase, ... Authors: Zhou, A, Feng, L. Deposit date: 2019-03-22 Release date: 2019-10-30 Last modified: 2020-05-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6RNW	The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) in complex with NADP. Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase Authors: Levy, C.W. Deposit date: 2019-05-09 Release date: 2019-10-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6RNV	The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) Descriptor: CHLORIDE ION, Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) Authors: Levy, C.W. Deposit date: 2019-05-09 Release date: 2019-10-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6YC8	Crystal structure of KRED1-Pglu enzyme Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... Authors: Di Pisa, F. Deposit date: 2020-03-18 Release date: 2021-02-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction. Bioorg.Chem., 108, 2021

 

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