Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6P57
DownloadVisualize
BU of 6p57 by Molmil
Crystal Structure of the Beta Subunit of Luteinizing Hormone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Lutropin subunit beta, alpha-D-mannopyranose, ...
Authors:McPherson, A.
Deposit date:2019-05-29
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:The Crystal Structure of the Beta Subunit of Luteinizing Hormone and a Model for the Intact Hormone
Curr Res Struct Biol, 2019
5BQ8
DownloadVisualize
BU of 5bq8 by Molmil
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form II
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Norrin
Authors:Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPU
DownloadVisualize
BU of 5bpu by Molmil
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form I
Descriptor: (GGL)EEE, (GGL)EEEEEE, Norrin
Authors:Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQB
DownloadVisualize
BU of 5bqb by Molmil
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III
Descriptor: CHLORIDE ION, CITRIC ACID, Norrin
Authors:Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
1HRP
DownloadVisualize
BU of 1hrp by Molmil
CRYSTAL STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN
Authors:Lapthorn, A.J, Harris, D.C, Isaacs, N.W.
Deposit date:1994-08-15
Release date:1994-11-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human chorionic gonadotropin.
Nature, 369, 1994
4AY9
DownloadVisualize
BU of 4ay9 by Molmil
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ...
Authors:Jiang, X, Liu, H, Chen, X, He, X.
Deposit date:2012-06-19
Release date:2012-08-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
1QFW
DownloadVisualize
BU of 1qfw by Molmil
TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ...
Authors:Tegoni, M, Spinelli, S, Cambillau, C.
Deposit date:1999-04-15
Release date:2000-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
1XWD
DownloadVisualize
BU of 1xwd by Molmil
Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle stimulating hormone receptor, ...
Authors:Fan, Q.R, Hendrickson, W.A.
Deposit date:2004-10-30
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of human follicle-stimulating hormone in complex with its receptor.
Nature, 433, 2005
4MY2
DownloadVisualize
BU of 4my2 by Molmil
Crystal Structure of Norrin in fusion with Maltose Binding Protein
Descriptor: Maltose-binding periplasmic protein, Norrin fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Ke, J, Jurecky, C, Chen, C, Gu, X, Parker, N, Williams, B.O, Melcher, K, Xu, H.E.
Deposit date:2013-09-27
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.
Genes Dev., 27, 2013
4MQW
DownloadVisualize
BU of 4mqw by Molmil
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ...
Authors:Jiang, X, Liu, H, Chen, X, He, X.
Deposit date:2013-09-16
Release date:2014-04-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
1FL7
DownloadVisualize
BU of 1fl7 by Molmil
HUMAN FOLLICLE STIMULATING HORMONE
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE STIMULATING PROTEIN ALPHA CHAIN, ...
Authors:Fox, K.M, Dias, J.A, Van Roey, P.
Deposit date:2000-08-11
Release date:2001-03-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structure of human follicle-stimulating hormone.
Mol.Endocrinol., 15, 2001
1HCN
DownloadVisualize
BU of 1hcn by Molmil
STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN
Authors:Wu, H, Lustbader, J.W, Liu, Y, Canfield, R.E, Hendrickson, W.A.
Deposit date:1994-07-01
Release date:1994-09-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2, 1994
8END
DownloadVisualize
BU of 8end by Molmil
Crystal structure of LGR ligand alpha2/beta5 from C. elegans in crystal form 1 (SeMet)
Descriptor: Bursicon, Cys_knot domain-containing protein
Authors:Gong, Z, Hendrickson, W.A.
Deposit date:2022-09-29
Release date:2023-01-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Crystal structure of LGR ligand alpha2/beta5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones
Proc Natl Acad Sci U S A, 120, 2023
8ENF
DownloadVisualize
BU of 8enf by Molmil
Crystal structure of LGR ligand alpha2/beta5 from C. elegans in crystal form 1 (native)
Descriptor: Bursicon, Cys_knot domain-containing protein
Authors:Gong, Z, Hendrickson, W.A.
Deposit date:2022-09-29
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Crystal structure of LGR ligand alpha2/beta5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones
Proc Natl Acad Sci U S A, 120, 2023
8ENB
DownloadVisualize
BU of 8enb by Molmil
Crystal structure of LGR ligand alpha2/beta5 from C. elegans in crystal form 2
Descriptor: Bursicon, Cys_knot domain-containing protein
Authors:Gong, Z, Hendrickson, W.A.
Deposit date:2022-09-29
Release date:2023-01-11
Last modified:2023-04-26
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of LGR ligand alpha2/beta5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones
Proc Natl Acad Sci U S A, 120, 2023
5BQE
DownloadVisualize
BU of 5bqe by Molmil
Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 -Methylated form
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQC
DownloadVisualize
BU of 5bqc by Molmil
Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, ...
Authors:Chang, T.-H, Hsieh, F.-L, Zebisch, M, Harlos, K, Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5CL1
DownloadVisualize
BU of 5cl1 by Molmil
Complex structure of Norrin with human Frizzled 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Maltose-binding periplasmic protein,Norrin
Authors:Wang, Z, Ke, J, Shen, G, Cheng, Z, Xu, H.E, Xu, W.
Deposit date:2015-07-16
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
8I2G
DownloadVisualize
BU of 8i2g by Molmil
FSHR-Follicle stimulating hormone-compound 716340-Gs complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
Deposit date:2023-01-14
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
7T9I
DownloadVisualize
BU of 7t9i by Molmil
Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein hormones alpha chain, ...
Authors:Faust, B, Cheng, Y, Manglik, A.
Deposit date:2021-12-19
Release date:2022-08-03
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Autoantibody mimicry of hormone action at the thyrotropin receptor.
Nature, 609, 2022
7UTZ
DownloadVisualize
BU of 7utz by Molmil
Human thyrotropin analog TR1402 bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein hormones alpha chain analog TR1402, ...
Authors:Faust, B, Cheng, Y, Manglik, A.
Deposit date:2022-04-28
Release date:2022-08-03
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Autoantibody mimicry of hormone action at the thyrotropin receptor.
Nature, 609, 2022
7XW5
DownloadVisualize
BU of 7xw5 by Molmil
TSHR-thyroid stimulating hormone-Gs-ML109 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Glycoprotein hormones alpha chain, ...
Authors:Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E.
Deposit date:2022-05-26
Release date:2022-08-24
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Hormone- and antibody-mediated activation of the thyrotropin receptor.
Nature, 609, 2022
7FII
DownloadVisualize
BU of 7fii by Molmil
luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex
Descriptor: Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Glycoprotein hormones alpha chain, ...
Authors:Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E.
Deposit date:2021-07-31
Release date:2021-09-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
7FIG
DownloadVisualize
BU of 7fig by Molmil
luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ...
Authors:Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E.
Deposit date:2021-07-31
Release date:2021-09-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
7FIH
DownloadVisualize
BU of 7fih by Molmil
luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex
Descriptor: 5-azanyl-N-tert-butyl-2-methylsulfanyl-4-[3-(2-morpholin-4-ylethanoylamino)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide, Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, ...
Authors:Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E.
Deposit date:2021-07-31
Release date:2021-09-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon