PDB: 299 件ウェブページステータス検索Chemie searchBIRD

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1BL8	POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS 分子名称: POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN) 著者 Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R. 登録日 1998-07-23 公開日 1998-07-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 1998
8THN	KcsA M96V mutant with Y78ester in High K+ 分子名称: KcsA Fab Heavy Chain, KcsA Fab Light Chain, POTASSIUM ION, ... 著者 Reddi, R, Valiyaveetil, F.I. 登録日 2023-07-17 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds. J.Biol.Chem., 300, 2023
4BW5	Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CADMIUM ION, POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, ... 著者 Pike, A.C.W, Dong, Y.Y, Dong, L, Quigley, A, Shrestha, L, Mukhopadhyay, S, Strain-Damerell, C, Goubin, S, Grieben, M, Shintre, C.A, Mackenzie, A, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N, Carpenter, E.P. 登録日 2013-06-30 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac Science, 347, 2015
1F6G	POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD 分子名称: VOLTAGE-GATED POTASSIUM CHANNEL 著者 Cortes, D.M, Perozo, E. 登録日 2000-06-21 公開日 2001-02-21 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J.Gen.Physiol., 117, 2001
5J9P	KcsA in vitro 分子名称: Fab, POTASSIUM ION, pH-gated potassium channel KcsA 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2016-04-10 公開日 2016-07-20 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression. Biochemistry, 55, 2016
8A35	NaK C-DI mutant with Rb+ and Na+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2022-06-07 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
8A7X	NaK C-DI F92A mutant soaked in Cs+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, POTASSIUM ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2022-06-21 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
8AYP	NaK C-DI mutant with Rb+ and Ba2+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2022-09-02 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel. J.Chem.Inf.Model., 63, 2023
8AYQ	NaK C-DI mutant with Rb+ and Ca2+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2022-09-02 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel. J.Chem.Inf.Model., 63, 2023
6CPV	MicroED structure of NaK ion channel reveals a process of Na+ partition into the selectivity filter 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, SODIUM ION 著者 Liu, S, Gonen, T. 登録日 2018-03-14 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 ELECTRON CRYSTALLOGRAPHY (2.5 Å) 主引用文献 MicroED structure of the NaK ion channel reveals a Na+partition process into the selectivity filter. Commun Biol, 1, 2018
7SQW	Structure of the KcsA-W67F mutant with the activation gate in the closed conformation 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Fragment, KcsA potassium channel, ... 著者 Cuello, L.G, Labro, A.J. 登録日 2021-11-07 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels. Sci Adv, 8, 2022
4UUJ	POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... 著者 Lenaeus, M.J, Burdette, D, Wagner, T, Focia, P.J, Gross, A. 登録日 2014-07-29 公開日 2014-08-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
4WFH	Human TRAAK K+ channel in a Tl+ bound nonconductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
4WFG	Human TRAAK K+ channel in a Tl+ bound conductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
4WFE	Human TRAAK K+ channel in a K+ bound conductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
4WFF	Human TRAAK K+ channel in a K+ bound nonconductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
6RV3	Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... 著者 Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2019-05-30 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
6RV4	Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 2341237 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, ... 著者 Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2019-05-30 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
6RV2	Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... 著者 Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2019-05-30 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
6FIZ	Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, POTASSIUM ION, ... 著者 Napolitano, L.M.R, De March, M, Steiner, R.A, Onesti, S. 登録日 2018-01-19 公開日 2019-03-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+ To Be Published
5VKH	Closed conformation of KcsA Y82A-F103A mutant 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E, Cortes, D.M. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
5VK6	Open conformation of KcsA non-inactivating E71A mutant 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
5VKE	Open conformation of KcsA deep-inactivated 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E, Cortes, D.M. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
6U9Z	Wild-type MthK pore in 6 mM K+ 分子名称: Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION 著者 Posson, D.J, Nimigean, C.M. 登録日 2019-09-09 公開日 2020-11-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
6U9Y	Wild-type MthK pore in 11 mM K+ 分子名称: Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION 著者 Posson, D.J, Nimigean, C.M. 登録日 2019-09-09 公開日 2020-11-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020

 

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