1QQF
 
 | | N-TERMINALLY TRUNCATED C3D,G FRAGMENT OF THE COMPLEMENT SYSTEM | | 分子名称: | PROTEIN (COMPLEMENT C3DG) | | 著者 | Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Berni, R. | | 登録日 | 1999-06-04 | | 公開日 | 2000-07-31 | | 最終更新日 | 2015-01-21 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
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2WY7
 | | Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d revealing an alternative binding mode | | 分子名称: | COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN | | 著者 | Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M. | | 登録日 | 2009-11-13 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
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2WY8
 | | Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d | | 分子名称: | COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN | | 著者 | Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M. | | 登録日 | 2009-11-13 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
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7UE9
 | | Structure of anti-C3d Fab(3d8b) in complex with C3d | | 分子名称: | Complement C3dg fragment, Fab heavy chain, Fab light chain, ... | | 著者 | Olland, A.M, White, A, Suto, R.K. | | 登録日 | 2022-03-21 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Front Immunol, 13, 2022
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1C3D
 | | X-RAY CRYSTAL STRUCTURE OF C3D: A C3 FRAGMENT AND LIGAND FOR COMPLEMENT RECEPTOR 2 | | 分子名称: | C3D, GLYCEROL | | 著者 | Nagar, B, Jones, R.G, Diefenbach, R.J, Isenman, D.E, Rini, J.M. | | 登録日 | 1998-05-19 | | 公開日 | 1998-10-07 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.
Science, 280, 1998
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1QSJ
 | | N-TERMINALLY TRUNCATED C3DG FRAGMENT | | 分子名称: | COMPLEMENT C3 PRECURSOR | | 著者 | Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Folli, C, Berni, R. | | 登録日 | 1999-06-22 | | 公開日 | 2000-07-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
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6RMT
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7BAG
 | | C3b in complex with CP40 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETAMIDE, AMINO GROUP, ... | | 著者 | Lamers, C, Xue, X, Smiesko, M, van Son, H, Wagner, B, Sfyroera, G, Gros, P, Lambris, J, Ricklin, D. | | 登録日 | 2020-12-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Nat Commun, 13, 2022
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1GHQ
 | | CR2-C3D COMPLEX STRUCTURE | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, COMPLEMENT C3, CR2/CD121/C3D/EPSTEIN-BARR VIRUS RECEPTOR, ... | | 著者 | Szakonyi, G, Guthridge, J.M, Li, D, Holers, V.M, Chen, X.S. | | 登録日 | 2001-01-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure of complement receptor 2 in complex with its C3d ligand.
Science, 292, 2001
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3D5R
 | | Crystal Structure of Efb-C (N138A) / C3d Complex | | 分子名称: | Complement C3, Fibrinogen-binding protein | | 著者 | Geisbrecht, B.V. | | 登録日 | 2008-05-16 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
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3OXU
 | | Complement components factor H CCP19-20 and C3d in complex | | 分子名称: | Complement C3, GLYCEROL, HF protein | | 著者 | Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. | | 登録日 | 2010-09-22 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for engagement by complement factor H of C3b on a self surface.
Nat.Struct.Mol.Biol., 18, 2011
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4ONT
 | | Ternary host recognition complex of complement factor H, C3d, and sialic acid | | 分子名称: | Complement C3d fragment, Complement factor H, GLYCEROL, ... | | 著者 | Blaum, B.S, Stehle, T.S. | | 登録日 | 2014-01-29 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for sialic acid-mediated self-recognition by complement factor H.
Nat.Chem.Biol., 11, 2015
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2GOX
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4ZH1
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3D5S
 | | Crystal Structure of Efb-C (R131A) / C3d Complex | | 分子名称: | Complement C3, Fibrinogen-binding protein | | 著者 | Geisbrecht, B.V. | | 登録日 | 2008-05-16 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
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7AD7
 | | Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R. | | 登録日 | 2020-09-14 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
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1HZF
 | | C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A | | 分子名称: | COMPLEMENT FACTOR C4A | | 著者 | van den Elsen, J.M.H, Martin, A, Wong, V, Clemenza, L, Rose, D.R, Isenman, D.E. | | 登録日 | 2001-01-24 | | 公開日 | 2002-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
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2XQW
 | | Structure of Factor H domains 19-20 in complex with complement C3d | | 分子名称: | COMPLEMENT C3, COMPLEMENT FACTOR H | | 著者 | Kajander, T, Lehtinen, M.J, Hyvarinen, S, Bhattacharjee, A, Leung, E, Isenman, D.E, Meri, S, Jokiranta, T.S, Goldman, A. | | 登録日 | 2010-09-07 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | | 主引用文献 | Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3RJ3
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6RMU
 | | Crystal structure of disulphide-linked human C3d dimer in complex with Staphylococcus aureus complement subversion protein Sbi-IV | | 分子名称: | 1,2-ETHANEDIOL, Complement C3, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J. | | 登録日 | 2019-05-07 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap
Front Immunol, 13, 2022
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5FO8
 | | Crystal Structure of Human Complement C3b in Complex with MCP (CCP1-4) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3, ... | | 著者 | Forneris, F, Wu, J, Xue, X, Gros, P. | | 登録日 | 2015-11-18 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
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4ZIQ
 | | Crystal structure of trypsin activated alpha-2-macroglobulin from Escherichia coli. | | 分子名称: | CHLORIDE ION, GLYCEROL, Uncharacterized lipoprotein YfhM | | 著者 | Garcia-Ferrer, I, Arede, P, Gomez-Blanco, J, Luque, D, Duquerroy, S, Caston, J.R, Goulas, T, Gomis-Ruth, X.F. | | 登録日 | 2015-04-28 | | 公開日 | 2015-06-10 | | 最終更新日 | 2015-07-15 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
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7OP0
 | | Crystal structure of complement C5 in complex with chemically synthesized K92 knob domain. | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, ... | | 著者 | Macpherson, A, van der Elsen, J.M.H, Schulze, M.E, Birtley, J.R. | | 登録日 | 2021-05-28 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | The Chemical Synthesis of Knob Domain Antibody Fragments.
Acs Chem.Biol., 16, 2021
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5HCC
 | | Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3. | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jore, M.M, Johnson, S, Lea, S.M. | | 登録日 | 2016-01-04 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
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7PI6
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