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8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
1ACC
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BU of 1acc by Molmil
ANTHRAX PROTECTIVE ANTIGEN
分子名称: ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
著者Petosa, C, Liddington, R.C.
登録日1997-02-05
公開日1998-02-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
4H2A
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BU of 4h2a by Molmil
Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Protective antigen
著者Baker, P.J, Sorrell, F.J.
登録日2012-09-12
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
TO BE PUBLISHED
4NAM
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BU of 4nam by Molmil
1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y)
分子名称: CALCIUM ION, Protective antigen
著者Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G.
登録日2013-10-22
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献(19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability.
Biochemistry, 53, 2014
5FR3
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BU of 5fr3 by Molmil
X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)
分子名称: CALCIUM ION, GLYCEROL, PROTECTIVE ANTIGEN
著者Ganesan, A, Siekierska, A, Beerten, J, Brams, M, van Durme, J, De Baets, G, van der Kant, R, Gallardo, R, Ramakers, M, Langenberg, T, Wilkinson, H, De Smet, F, Ulens, C, Rousseau, F, Schymkowitz, J.
登録日2015-12-15
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.935 Å)
主引用文献Structural Hot Spots for the Solubility of Globular Proteins
Nat.Commun., 7, 2016
2J42
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BU of 2j42 by Molmil
low quality crystal structure of the transport component C2-II of the C2-toxin from Clostridium botulinum
分子名称: C2 TOXIN COMPONENT-II
著者Schleberger, C, Hochmann, H, Barth, H, Aktories, K, Schulz, G.E.
登録日2006-08-24
公開日2006-10-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
J.Mol.Biol., 364, 2006
7KXR
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BU of 7kxr by Molmil
Protective antigen pore translocating lethal factor N-terminal domain
分子名称: CALCIUM ION, Lethal factor, Protective antigen
著者Machen, A.J, Freudenthal, B.D.
登録日2020-12-04
公開日2021-07-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism.
Sci Rep, 11, 2021
4EE2
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BU of 4ee2 by Molmil
Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution
分子名称: CALCIUM ION, Protective antigen
著者Kintzer, A.F, Krantz, B.A.
登録日2012-03-28
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation.
Proc.Natl.Acad.Sci.USA, 109, 2012
7MJR
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BU of 7mjr by Molmil
Vip4Da2 toxin structure
分子名称: CALCIUM ION, SULFATE ION, Vip4Da1 protein
著者Rydel, T.J, Duda, D, Zheng, M, Henry, A.
登録日2021-04-20
公開日2021-05-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Plos One, 16, 2021
7O85
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BU of 7o85 by Molmil
Anthrax toxin prepore in complex with the neutralizing Fab cAb29
分子名称: CALCIUM ION, Fab, Protective antigen PA-63
著者Hoelzgen, F, Zalk, R, Alcalay, R, Cohen-Schwartz, S, Garau, G, Shahar, A, Mazor, O, Frank, G.A.
登録日2021-04-14
公開日2021-04-28
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Neutralization of the anthrax toxin by antibody-mediated stapling of its membrane-penetrating loop.
Acta Crystallogr D Struct Biol, 77, 2021
6ZXK
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BU of 6zxk by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXL
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BU of 6zxl by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXJ
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BU of 6zxj by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked)
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6KLW
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BU of 6klw by Molmil
Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem
分子名称: CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib
著者Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
登録日2019-07-30
公開日2020-01-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
6KLX
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BU of 6klx by Molmil
Pore structure of Iota toxin binding component (Ib)
分子名称: CALCIUM ION, Iota toxin component Ib
著者Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
登録日2019-07-30
公開日2020-01-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
6KLO
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BU of 6klo by Molmil
Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem
分子名称: CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib
著者Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
登録日2019-07-30
公開日2020-01-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
1TZO
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BU of 1tzo by Molmil
Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
分子名称: CALCIUM ION, Protective antigen
著者Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J.
登録日2004-07-10
公開日2004-08-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
3TEX
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BU of 3tex by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution
分子名称: CALCIUM ION, Protective antigen
著者Feld, G.K, Krantz, B.A.
登録日2011-08-15
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEW
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BU of 3tew by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution
分子名称: 2-METHOXYETHANOL, CALCIUM ION, Protective antigen
著者Feld, G.K, Krantz, B.A.
登録日2011-08-15
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEZ
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BU of 3tez by Molmil
Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution
分子名称: 2-METHOXYETHANOL, ACETONE, CALCIUM ION, ...
著者Feld, G.K, Krantz, B.A.
登録日2011-08-15
公開日2011-10-26
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEY
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BU of 3tey by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution
分子名称: CALCIUM ION, Protective antigen
著者Feld, G.K, Krantz, B.A.
登録日2011-08-15
公開日2011-10-26
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
7VNJ
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BU of 7vnj by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with short stem
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosyltransferase enzymatic component, CALCIUM ION
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2021-10-11
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7VNN
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BU of 7vnn by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with long stem
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, CALCIUM ION, CdtA
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2021-10-11
公開日2022-10-26
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
3HVD
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BU of 3hvd by Molmil
The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes
分子名称: CALCIUM ION, Protective antigen
著者Kintzer, A.F, Dong, K.C, Berger, J.M, Krantz, B.A.
登録日2009-06-15
公開日2009-08-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.209 Å)
主引用文献The protective antigen component of anthrax toxin forms functional octameric complexes.
J.Mol.Biol., 392, 2009
3J9C
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BU of 3j9c by Molmil
CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution
分子名称: CALCIUM ION, Protective antigen PA-63
著者Jiang, J, Pentelute, B.L, Collier, R.J, Zhou, Z.H.
登録日2014-12-25
公開日2015-03-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Atomic structure of anthrax protective antigen pore elucidates toxin translocation.
Nature, 521, 2015

 

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