PDB: 205 件ウェブページステータス検索Chemie searchBIRD

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4LND	Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor 分子名称: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION 著者 Manvilla, B.A, Pozharski, E, Toth, E.A, Drohat, A.C. 登録日 2013-07-11 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor. Acta Crystallogr.,Sect.D, 69, 2013
3TEB	endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b 分子名称: Endonuclease/exonuclease/phosphatase, MAGNESIUM ION 著者 Chang, C, Bigelow, L, Muniez, I, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-08-12 公開日 2011-08-31 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Crystal structure of endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b To be Published
2O3H	Crystal structure of the human C65A Ape 分子名称: ACETATE ION, DNA-(apurinic or apyrimidinic site) lyase, SAMARIUM (III) ION 著者 Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. 登録日 2006-12-01 公開日 2007-12-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease Mutat.Res., 643, 2008
3U8U	Crystal structure of Human Apurinic/Apyridinimic Endonuclease, Ape1 in a new crystal form 分子名称: CHLORIDE ION, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION 著者 Agarwal, R, Naidu, M.D. 登録日 2011-10-17 公開日 2011-10-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of Human Apurinic/Apyridinimic Endonuclease, Ape1 in a new crystal form To be Published
2O3C	Crystal structure of zebrafish Ape 分子名称: APEX nuclease 1, LEAD (II) ION 著者 Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. 登録日 2006-12-01 公開日 2007-12-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease Mutat.Res., 643, 2008
1VYB	Endonuclease domain of human LINE1 ORF2p 分子名称: GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ... 著者 Weichenrieder, O, Repanas, K, Perrakis, A. 登録日 2004-04-25 公開日 2004-06-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon. Structure, 12, 2004
3DNI	CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE OF DNASE I AT 2 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, DEOXYRIBONUCLEASE I, alpha-D-galactopyranose-(1-6)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Oefner, C, Suck, D. 登録日 1992-08-20 公開日 1994-01-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic refinement and structure of DNase I at 2 A resolution. J.Mol.Biol., 192, 1986
1HD7	A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism 分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION 著者 Beernink, P.T, Segelke, B.W, Rupp, B. 登録日 2000-11-09 公開日 2001-02-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307, 2001
1I9Y	CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN 分子名称: PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE 著者 Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H. 登録日 2001-03-21 公開日 2001-05-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell(Cambridge,Mass.), 105, 2001
1I9Z	CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN IN COMPLEX WITH INOSITOL (1,4)-BISPHOSPHATE AND CALCIUM ION 分子名称: CALCIUM ION, D-MYO-INOSITOL-1,4-BISPHOSPHATE, PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE 著者 Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H. 登録日 2001-03-21 公開日 2001-05-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell(Cambridge,Mass.), 105, 2001
6FK5	Structure of 3' phosphatase NExo (D146N) from Neisseria bound to DNA substrate in presence of magnesium ion 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), MAGNESIUM ION, ... 著者 Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S. 登録日 2018-01-23 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Res., 46, 2018
6FKE	Structure of 3' phosphatase NExo (D146N) from Neisseria bound to product DNA hairpin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*A)-3'), Exodeoxyribonuclease III, ... 著者 Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S. 登録日 2018-01-23 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Res., 46, 2018
6FK4	Structure of 3' phosphatase NExo (WT) from Neisseria bound to DNA substrate 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*GP*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), Exodeoxyribonuclease III 著者 Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S. 登録日 2018-01-23 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.297 Å) 主引用文献 Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Res., 46, 2018
2V0R	crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease 分子名称: LTX, SULFATE ION 著者 Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O. 登録日 2007-05-17 公開日 2007-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease Nucleic Acids Res., 35, 2007
2V0S	crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease 分子名称: GLYCEROL, LR1, MANGANESE (II) ION, ... 著者 Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O. 登録日 2007-05-17 公開日 2007-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease. Nucleic Acids Res., 35, 2007
2UYR	Crystal structure of Bacillus cereus sphingomyelinase mutant :N57A 分子名称: MAGNESIUM ION, SPHINGOMYELINASE C 著者 Oda, M, Tsuge, H, Sakurai, J. 登録日 2007-04-12 公開日 2008-05-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Bacillus Cereus Sphingomyelinase Mutant : N57A To be Published
2VOA	Structure of an AP Endonuclease from Archaeoglobus fulgidus 分子名称: 5'-D(*CP*GP*GP*CP*TP*AP*CP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*GP*TP*AP*GP*CP*CP*GP)-3', EXODEOXYRIBONUCLEASE III 著者 Kuettner, E.B, Schmiedel, R, Greiner-Stoffele, T, Strater, N. 登録日 2008-02-11 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and Function of the Abasic Site Specificity Pocket of an Ap Endonuclease from Archaeoglobus Fulgidus. DNA Repair, 8, 2009
3L1W	The crystal structure of a functionally unknown conserved protein from Enterococcus faecalis V583 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, SULFATE ION, ... 著者 Tan, K, Rakowski, E, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-12-14 公開日 2010-01-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The crystal structure of a functionally unknown conserved protein from Enterococcus faecalis V583 To be Published
4PUQ	Mus Musculus Tdp2 reaction product complex with 5'-phosphorylated RNA/DNA, glycerol, and Mg2+ 分子名称: ACETATE ION, DNA/RNA hybrid, GLYCEROL, ... 著者 Schellenberg, M.J, Williams, R.S. 登録日 2014-03-13 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2DNA and Top2RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2). J.Biol.Chem., 289, 2014
4QHE	Crystal structure of Mg2+ bound human APE1 分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION 著者 He, H, Chen, Q, Georgiadis, M.M. 登録日 2014-05-28 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
4QHD	Crystal structure of apo human APE1 分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase 著者 He, H, Chen, Q, Georgiadis, M.M. 登録日 2014-05-28 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
4QH9	Crystal structure of Mn2+ bound human APE1 分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION 著者 Chen, Q, He, H, Georgiadis, M.M. 登録日 2014-05-27 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.175 Å) 主引用文献 High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
7CD6	mAPE1-recessed dsDNA product complex 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*AP*C)-3'), DNA-(apurinic or apyrimidinic site) endonuclease 著者 Liu, T.C, Hsiao, Y.Y. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021
3MPR	Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A 分子名称: ACETIC ACID, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-04-27 公開日 2010-05-26 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Northeast Structural Genomics Consortium Target BtR318A To be Published
7CD5	mAPE1-blunt-ended dsDNA product complex 分子名称: DNA(5'-D(*CP*GP*TP*AP*AP*TP*AP*CP*G)-3'), DNA-(apurinic or apyrimidinic site) endonuclease 著者 Liu, T.C, Hsiao, Y.Y. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021

 

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