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4WWX
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BU of 4wwx by Molmil
Crystal structure of the core RAG1/2 recombinase
分子名称: V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, ZINC ION
著者Kim, M.S, Lapkouski, M, Yang, W, Gellert, M.
登録日2014-11-12
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2001 Å)
主引用文献Crystal structure of the V(D)J recombinase RAG1-RAG2.
Nature, 518, 2015
3JBW
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BU of 3jbw by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (with NBD, no symmetry)
分子名称: 12-RSS signal end forward strand, 5'-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', Nicked 12-RSS intermediate reverse strand, ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-21
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBY
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BU of 3jby by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (C2 symmetry)
分子名称: '-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', CALCIUM ION, ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-22
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBX
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BU of 3jbx by Molmil
Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry)
分子名称: 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', 5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3', 5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3', ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-22
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
6CG0
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BU of 6cg0 by Molmil
Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A)
分子名称: CALCIUM ION, DNA (30-MER), DNA (41-MER), ...
著者Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W.
登録日2018-02-19
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIL
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BU of 6cil by Molmil
PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+
分子名称: High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIJ
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BU of 6cij by Molmil
Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A)
分子名称: CALCIUM ION, DNA (30-MER), DNA (41-MER), ...
著者Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIK
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BU of 6cik by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+
分子名称: DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIM
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BU of 6cim by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-nicked/intact 12/23RSS complex in Mn2+
分子名称: DNA (5'-D(*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 23RSS substrate forward strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
5ZE2
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BU of 5ze2 by Molmil
Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C
分子名称: 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ...
著者Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
登録日2018-02-25
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZDZ
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BU of 5zdz by Molmil
Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (30-MER), ...
著者Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
登録日2018-02-25
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZE0
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BU of 5ze0 by Molmil
Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+
分子名称: 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ...
著者Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
登録日2018-02-25
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZE1
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BU of 5ze1 by Molmil
Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C
分子名称: 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ...
著者Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
登録日2018-02-25
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
6DBR
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BU of 6dbr by Molmil
Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS
分子名称: CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBL
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BU of 6dbl by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (5.001 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBQ
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BU of 6dbq by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBW
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BU of 6dbw by Molmil
Cryo-EM structure of RAG in complex with 12-RSS substrate DNA
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBT
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BU of 6dbt by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBX
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BU of 6dbx by Molmil
Cryo-EM structure of RAG in complex with 12-RSS substrate DNA
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBV
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BU of 6dbv by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.291 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBU
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BU of 6dbu by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBI
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BU of 6dbi by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates
分子名称: CALCIUM ION, Forward strand of 12-RSS signal end, Forward strand of 23-RSS signal end, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBJ
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BU of 6dbj by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates
分子名称: CALCIUM ION, Forward stand of RSS signal end, Forward strand of coding flank, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBO
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BU of 6dbo by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6OEP
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BU of 6oep by Molmil
Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020

 

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