1B3U
 
 | | CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA | | 分子名称: | PROTEIN (PROTEIN PHOSPHATASE PP2A) | | 著者 | Groves, M.R, Hanlon, N, Turowski, P, Hemmings, B, Barford, D. | | 登録日 | 1998-12-14 | | 公開日 | 1999-04-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs.
Cell(Cambridge,Mass.), 96, 1999
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6MQ5
 | | Structure of human CLASP1 TOG1 | | 分子名称: | CLIP-associating protein 1 | | 著者 | Leano, J.B, Slep, K.C. | | 登録日 | 2018-10-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.146 Å) | | 主引用文献 | Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1.
Plos One, 14, 2019
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7XVK
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6XU2
 | | Human karyopherin RanBP5 (isoform-3) | | 分子名称: | Antipain, Importin-5, NICKEL (II) ION | | 著者 | Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T. | | 登録日 | 2020-01-17 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.834 Å) | | 主引用文献 | X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking.
J.Mol.Biol., 432, 2020
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5OWU
 | | Kap95:Nup1 complex | | 分子名称: | Importin subunit beta-1, Nucleoporin NUP1 | | 著者 | Stewart, M. | | 登録日 | 2017-09-04 | | 公開日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p.
J. Mol. Biol., 349, 2005
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3ND2
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6EF4
 | | Crystal structure of mouse PP2A Aalpha P179R mutant | | 分子名称: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | | 著者 | Wang, Z, Shen, G, Xu, W. | | 登録日 | 2018-08-16 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | The Highly Recurrent PP2A A alpha-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.
Cancer Res., 79, 2019
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4OO6
 | | Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) | | 分子名称: | RNA-binding protein 39, Transportin-1 | | 著者 | Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) | | 登録日 | 2014-01-30 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
to be published
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6IUR
 | | A phosphatase complex STRN3-PP2Aa | | 分子名称: | PP2A scaffolding subunit, PROPANE, Striatin-3 | | 著者 | Tang, Y, Zhou, Z.C. | | 登録日 | 2018-11-30 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | | 主引用文献 | Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Cancer Cell, 38, 2020
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5J3V
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7CYL
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6XTE
 | | Human karyopherin RanBP5 (isoform-1) | | 分子名称: | Antipain, CHLORIDE ION, Importin-5, ... | | 著者 | Swale, C, McCarthy, A.A, Ruigrok, R.W.H, Crepin, T. | | 登録日 | 2020-01-16 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking.
J.Mol.Biol., 432, 2020
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2DB0
 | | Crystal structure of PH0542 | | 分子名称: | 253aa long hypothetical protein | | 著者 | Nishino, A, Handa, N, Kishishita, S, Murayama, K, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-14 | | 公開日 | 2006-06-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of PH0542
To be Published
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4FDD
 | | Crystal structure of KAP beta2-PY-NLS | | 分子名称: | RNA-binding protein FUS, Transportin-1 | | 著者 | Zhang, Z.C, Chook, Y.M. | | 登録日 | 2012-05-28 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQ3
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4JLQ
 | | Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2 | | 分子名称: | Nuclear polyadenylated RNA-binding protein NAB2, Transportin-1 | | 著者 | Sampathkumar, P, Gizzi, A, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) | | 登録日 | 2013-03-12 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
J.Struct.Funct.Genom., 14, 2013
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5YVI
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2H4M
 | | Karyopherin Beta2/Transportin-M9NLS | | 分子名称: | Heterogeneous nuclear ribonucleoprotein A1, Transportin-1 | | 著者 | Chook, Y.M, Cansizoglu, A.E. | | 登録日 | 2006-05-24 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
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5TQC
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5VCH
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5VE8
 | | Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H3 1-28 | | 分子名称: | Histone H3, Kap123 | | 著者 | An, S, Yoon, J, Song, J.-J, Cho, U.-S. | | 登録日 | 2017-04-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
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5W0V
 | | Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H4 1-34 | | 分子名称: | Histone H4 1-34, Kap123 | | 著者 | An, S, Yoon, J, Song, J.-J, Cho, U.-S. | | 登録日 | 2017-05-31 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.821 Å) | | 主引用文献 | Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
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2Z5N
 | | Complex of Transportin 1 with hnRNP D NLS | | 分子名称: | Heterogeneous nuclear ribonucleoprotein D0, Transportin-1 | | 著者 | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | | 登録日 | 2007-07-14 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
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2Z5J
 | | Free Transportin 1 | | 分子名称: | Transportin-1 | | 著者 | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | | 登録日 | 2007-07-13 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
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2Z5O
 | | Complex of Transportin 1 with JKTBP NLS | | 分子名称: | Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1 | | 著者 | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | | 登録日 | 2007-07-14 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
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