3MXG
| Structure of Shiga Toxin type 2 (Stx2) B Pentamer Mutant Q40L | 分子名称: | D-xylose, Shiga-like toxin 2 subunit B | 著者 | Kovall, R.A, Vander Wielen, B.D, Friedmann, D.R, Flagler, M.J. | 登録日 | 2010-05-07 | 公開日 | 2011-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2. Plos One, 5, 2010
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6FE4
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2XSC
| Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli | 分子名称: | SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION | 著者 | Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J. | 登録日 | 2010-09-27 | 公開日 | 2010-10-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | 主引用文献 | Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli. Nature, 355, 1992
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4ULL
| SOLUTION NMR STRUCTURE OF VEROTOXIN-1 B-SUBUNIT FROM E. COLI, 5 STRUCTURES | 分子名称: | Shiga toxin 1B | 著者 | Richardson, J.M, Evans, P.D, Homans, S.W, Donohue-Rolfe, A. | 登録日 | 1996-12-17 | 公開日 | 1997-04-01 | 最終更新日 | 2019-12-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the carbohydrate-binding B-subunit homopentamer of verotoxin VT-1 from E. coli. Nat.Struct.Biol., 4, 1997
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2BOS
| A MUTANT SHIGA-LIKE TOXIN IIE BOUND TO ITS RECEPTOR | 分子名称: | N-BUTANE, PROTEIN (SHIGA-LIKE TOXIN IIE B SUBUNIT), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | 著者 | Ling, H, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | 登録日 | 1998-10-20 | 公開日 | 1999-10-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A mutant Shiga-like toxin IIe bound to its receptor Gb(3): structure of a group II Shiga-like toxin with altered binding specificity. Structure Fold.Des., 8, 2000
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2C5C
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1BOS
| SHIGA-LIKE TOXIN COMPLEXED WITH ITS RECEPTOR | 分子名称: | SHIGA-LIKE TOXIN I B SUBUNIT, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Ling, H, Boodhoo, A, Hazes, B, Cummings, M.D, Armstrong, G.D, Brunton, J.L, Read, R.J. | 登録日 | 1998-01-13 | 公開日 | 1999-02-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3. Biochemistry, 37, 1998
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1C48
| MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T) | 分子名称: | PROTEIN (SHIGA-LIKE TOXIN I B SUBUNIT) | 著者 | Ling, H, Bast, D, Brunton, J.L, Read, R.J. | 登録日 | 1999-08-11 | 公開日 | 2000-08-16 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate To be Published
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1C4Q
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1QNU
| Shiga-Like Toxin I B Subunit Complexed with the Bridged-Starfish Inhibitor | 分子名称: | ETHYL-CARBAMIC ACID METHYL ESTER, METHYL-CARBAMIC ACID ETHYL ESTER, Shiga toxin 1 variant B subunit, ... | 著者 | Pannu, N.S, Hayakawa, K, Read, R.J. | 登録日 | 1999-10-21 | 公開日 | 2000-04-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands. Nature, 403, 2000
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1QOH
| A MUTANT SHIGA-LIKE TOXIN IIE | 分子名称: | SHIGA-LIKE TOXIN IIE B SUBUNIT | 著者 | Pannu, N.S, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | 登録日 | 1999-11-08 | 公開日 | 2000-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A Mutant Shiga-Like Toxin Iie Bound to its Receptor Gb(3): Structure of a Group II Shiga-Like Toxin with Altered Binding Specificity Structure, 8, 2000
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1CZG
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1CZW
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1D1I
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1CQF
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1D1K
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6X6H
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6U3U
| Crystal Structure of Shiga Toxin 2K | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Shiga toxin 2K subunit A, ... | 著者 | Zhang, Y.Z, He, X.H. | 登録日 | 2019-08-22 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.287 Å) | 主引用文献 | Structural and Functional Characterization of Stx2k, a New Subtype of Shiga Toxin 2. Microorganisms, 8, 2019
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1DM0
| SHIGA TOXIN | 分子名称: | SHIGA TOXIN A SUBUNIT, SHIGA TOXIN B SUBUNIT | 著者 | Fraser, M.E, Chernaia, M.M, Kozlov, Y.V, James, M.N. | 登録日 | 1999-12-13 | 公開日 | 1999-12-30 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution. Nat.Struct.Biol., 1, 1994
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4M1U
| The crystal structure of Stx2 and a disaccharide ligand | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 A-subunit, ... | 著者 | Yin, J, James, M.N.G, Jacobson, J.M, Kitov, P.I, Bundle, D.R, Mulvey, G, Armstrong, G. | 登録日 | 2013-08-04 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor. J.Biol.Chem., 289, 2014
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7D6Q
| Crystal structure of the Stx2a | 分子名称: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 B subunit, rRNA N-glycosylase | 著者 | Takahashi, M, Tamada, M, Hibino, M, Senda, M, Okuda, A, Miyazawa, A, Senda, T, Nishikawa, K. | 登録日 | 2020-10-01 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin. Commun Biol, 4, 2021
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7D6R
| Crystal structure of the Stx2a complexed with MMA betaAla peptide | 分子名称: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, MMA betaAla peptide, Shiga toxin 2 B subunit, ... | 著者 | Takahashi, M, Tamada, M, Hibino, M, Senda, M, Okuda, A, Miyazawa, A, Senda, T, Nishikawa, K. | 登録日 | 2020-10-01 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin. Commun Biol, 4, 2021
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7U6V
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7UJJ
| Stx2a and DARPin complex | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | 著者 | Jiang, M, Zhang, J. | 登録日 | 2022-03-30 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits. Bioengineering (Basel), 9, 2022
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4P2C
| Complex of Shiga toxin 2e with a neutralizing single-domain antibody | 分子名称: | Nanobody 1, Anti-F4+ETEC bacteria VHH variable region, Shiga toxin 2e, ... | 著者 | Lo, A.W.H, Moonens, K, De Kerpel, M, Brys, L, Pardon, E, Remaut, H, De Greve, H. | 登録日 | 2014-03-03 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain. J.Biol.Chem., 289, 2014
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