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2PTL
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BU of 2ptl by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN-BINDING DOMAIN OF PROTEIN L. COMPARISON WITH THE IGG-BINDING DOMAINS OF PROTEIN G
分子名称: PROTEIN L
著者Wikstroem, M, Drakenberg, T, Forsen, S, Sjoebring, U, Bjoerck, L.
登録日1994-08-12
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G.
Biochemistry, 33, 1994
1YMH
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BU of 1ymh by Molmil
anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W
分子名称: Fab 16D9D6, heavy chain, light chain, ...
著者Granata, V, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A.
登録日2005-01-21
公開日2005-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Comparison of the crystallization and crystal packing of two Fab single-site mutant protein L complexes.
Acta Crystallogr.,Sect.D, 61, 2005
2JZP
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BU of 2jzp by Molmil
NMR solution structure of Kx5Q ProtL mutant
分子名称: Protein L
著者Lopez-Mendez, N, Tadeo, X, Castano, D, Pons, M, Millet Aguilar-Galindo, O.
登録日2008-01-11
公開日2009-01-13
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Protein stabilization and the hofmeister effect: the role of hydrophobic solvation
Biophys.J., 97, 2009
2KAC
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BU of 2kac by Molmil
NMR solution structure of KX6E protL mutant
分子名称: Protein L
著者Lopez-Mendez, B, Tadeo, X, Pons, M, Millet, O.
登録日2008-11-04
公開日2009-10-20
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structural basis for the aminoacid composition of proteins from halophilic archea
Plos Biol., 7, 2009
1HZ5
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CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS, WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
分子名称: PROTEIN L, ZINC ION
著者O'Neill, J.W, Kim, D.E, Baker, D, Zhang, K.Y.J.
登録日2001-01-23
公開日2001-04-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1HZ6
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CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
分子名称: PROTEIN L
著者O'Neill, J.W, Kim, D.E, Baker, D, Zhang, K.Y.J.
登録日2001-01-23
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1JML
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Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design
分子名称: Protein L, ZINC ION
著者O'Neill, J.W, Kuhlman, B, Kim, D.E, Zhang, K.Y.J, Baker, D.
登録日2001-07-19
公開日2001-10-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conversion of monomeric protein L to an obligate dimer by computational protein design.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K50
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A V49A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus
分子名称: Protein L
著者O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
登録日2001-10-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K53
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Monomeric Protein L B1 Domain with a G15A Mutation
分子名称: Protein L, ZINC ION
著者O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
登録日2001-10-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K51
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A G55A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus
分子名称: Protein L, ZINC ION
著者O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
登録日2001-10-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K52
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Monomeric Protein L B1 Domain with a K54G mutation
分子名称: Protein L, ZINC ION
著者O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J.
登録日2001-10-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1KH0
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Accurate Computer Base Design of a New Backbone Conformation in the Second Turn of Protein L
分子名称: protein L
著者O'Neill, J.W, Kuhlman, B, Kim, D.E, Zhang, K.Y, Baker, D.
登録日2001-11-28
公開日2002-01-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Accurate computer-based design of a new backbone conformation in the second turn of protein L.
J.Mol.Biol., 315, 2002
1YNT
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BU of 1ynt by Molmil
Structure of the monomeric form of T. gondii SAG1 surface antigen bound to a human Fab
分子名称: 4F11E12 Fab variable heavy chain region, 4F11E12 Fab variable light chain region, CADMIUM ION, ...
著者Graille, M, Stura, E.A, Bossus, M, Muller, B.H, Letourneur, O, Battail-Poirot, N, Sibai, G, Rolland, D, Le Du, M.H, Ducancel, F.
登録日2005-01-25
公開日2005-12-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response
J.Mol.Biol., 354, 2005
1HEZ
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BU of 1hez by Molmil
Structure of P. magnus protein L bound to a human IgM Fab.
分子名称: HEAVY CHAIN OF IG, IMIDAZOLE, KAPPA LIGHT CHAIN OF IG, ...
著者Graille, M, Stura, E.A, Housden, N.G, Bottomley, S.P, Taussig, M.J, Sutton, B.J, Gore, M.G, Charbonnier, J.B.
登録日2000-11-27
公開日2001-08-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9, 2001
4HJG
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BU of 4hjg by Molmil
Meditope-enabled trastuzumab
分子名称: Immunoglobulin G-binding protein A, Protein L fragment, Trastuzumab heavy chain, ...
著者Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
登録日2012-10-12
公開日2013-10-09
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKZ
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BU of 4hkz by Molmil
Trastuzumab Fab complexed with Protein L and Protein A fragments
分子名称: CHLORIDE ION, Immunoglobulin G-binding protein A, Protein L fragment, ...
著者Avery, K.N, Zer, C, Bzymek, K.P, Williams, J.C.
登録日2012-10-15
公開日2013-10-09
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IOI
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Meditope-enabled trastuzumab in complex with CQFDLSTRRLKC
分子名称: Immunoglobulin G-binding protein A, Protein L, Trastuzumab heavy chain, ...
著者Bzymek, K.P, Zer, C, Avery, K.N, Williams, J.C.
登録日2013-01-07
公開日2013-10-09
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5U5F
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BU of 5u5f by Molmil
MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT IN COMPLEX WITH (Ac) CQFDA(PH)2STRRLRCGGSK
分子名称: 5-DIPHENYL LONG MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB FAB HEAVY CHAIN, ...
著者Bzymek, K.P, Avery, K.N, Zer, C, Williams, J.C.
登録日2016-12-06
公開日2018-03-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Meditope Enabled Trastuzumab I83E Variant In Complex With (Ac)Cqfda(Ph)2Strrlrcggsk
To Be Published
5U6A
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CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE
分子名称: Heavy Chain, Immunoglobulin G binding protein A, Light Chain, ...
著者Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
登録日2016-12-07
公開日2018-03-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.736 Å)
主引用文献Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-PEG3-Meditope
To Be Published
5U3D
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BU of 5u3d by Molmil
STRUCTURE OF MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT
分子名称: Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB FAB HEAVY CHAIN, MEMAB TRASTUZUMAB FAB LIGHT CHAIN I83E, ...
著者Bzymek, K.P, Avery, K.N, Zer, C, Williams, J.C.
登録日2016-12-01
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Meditope Enabled Trastuzumab I83E Variant
To Be Published
5U5M
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CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE
分子名称: AZIDO-PEG4-MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB, ...
著者Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
登録日2016-12-06
公開日2018-03-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-Meditope
To Be Published
6BAH
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BU of 6bah by Molmil
Trastuzumab Fab v3 with 5-diphenyl meditope variant
分子名称: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ...
著者Bzymek, K.P, King, J.D, Williams, J.C.
登録日2017-10-12
公開日2018-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6BAE
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Trastuzumab Fab v3 in complex with CQFDLSTRRLKC
分子名称: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
著者Bzymek, K.P, King, J.D, Williams, J.C.
登録日2017-10-12
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6B9Y
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Trastuzumab Fab v3 in complex with 5-phenyl meditope variant
分子名称: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
著者Bzymek, K.P, King, J.D, Williams, J.C.
登録日2017-10-11
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6B9Z
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Trastuzumab Fab v3
分子名称: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
著者Bzymek, K.P, King, J.D, Williams, J.C.
登録日2017-10-11
公開日2018-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018

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件を2024-03-27に公開中

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