7MLH
 
 | | Crystal structure of human IgE (2F10) in complex with Der p 2.0103 | | 分子名称: | CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ... | | 著者 | Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo.
Pnas Nexus, 1, 2022
|
|
5KWY
 | | Structure of human NPC1 middle lumenal domain bound to NPC2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Epididymal secretory protein E1, ... | | 著者 | Li, X. | | 登録日 | 2016-07-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6OY4
 | | Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1 | | 分子名称: | Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ... | | 著者 | Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M. | | 登録日 | 2019-05-14 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
|
|
1G13
 | | HUMAN GM2 ACTIVATOR STRUCTURE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GANGLIOSIDE M2 ACTIVATOR PROTEIN | | 著者 | Wright, C.S, Li, S.C, Rastinejad, F. | | 登録日 | 2000-10-10 | | 公開日 | 2001-04-11 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human GM2-activator protein with a novel beta-cup topology.
J.Mol.Biol., 304, 2000
|
|
3WEB
 | | Crystal structure of a Niemann-Pick type C2 protein from Japanese carpenter ant in complex with oleic acid | | 分子名称: | Niemann-Pick type C2 protein, OLEIC ACID | | 著者 | Fujimoto, Z, Tsuchiya, W, Ishida, Y, Yamazaki, T. | | 登録日 | 2013-07-02 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Niemann-Pick type C2 protein mediating chemical communication in the worker ant
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3WEA
 | |
6R4N
 | | Crystal structure of S. cerevisia Niemann-Pick type C protein NPC2 with ergosterol bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ERGOSTEROL, ... | | 著者 | Winkler, M.B.L, Kidmose, R.T, Pedersen, B.P. | | 登録日 | 2019-03-22 | | 公開日 | 2019-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins.
Cell, 179, 2019
|
|
6R4M
 | |
1TJJ
 | | Human GM2 Activator Protein PAF complex | | 分子名称: | (2R)-2-(acetyloxy)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Wright, C.S, Mi, L.-Z, Rastinejad, F. | | 登録日 | 2004-06-04 | | 公開日 | 2004-12-07 | | 最終更新日 | 2013-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor
J.Mol.Biol., 342, 2004
|
|
1KTJ
 | | X-ray Structure Of Der P 2, The Major House Dust Mite Allergen | | 分子名称: | ALLERGEN DER P 2 | | 著者 | Derewenda, U, Li, J, Derewenda, Z, Dauter, Z, Mueller, G.A, Rule, G.S, Benjamin, D.C. | | 登録日 | 2002-01-16 | | 公開日 | 2002-05-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
|
|
1WRF
 | | Refined solution structure of Der f 2, The Major Mite Allergen from Dermatophagoides farinae | | 分子名称: | Mite group 2 allergen Der f 2 | | 著者 | Ichikawa, S, Takai, T, Inoue, T, Yuuki, T, Okumura, Y, Ogura, K, Inagaki, F, Hatanaka, H. | | 登録日 | 2004-10-15 | | 公開日 | 2005-04-19 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Study on the Major Mite Allergen Der f 2: Its Refined Tertiary Structure, Epitopes for Monoclonal Antibodies and Characteristics Shared by ML Protein Group Members
J.Biochem.(Tokyo), 137, 2005
|
|
1AHK
 | | DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | DER F 2 | | 著者 | Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F. | | 登録日 | 1997-04-07 | | 公開日 | 1998-04-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
|
|
1AHM
 | | DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, 10 STRUCTURES | | 分子名称: | DER F 2 | | 著者 | Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F. | | 登録日 | 1997-04-07 | | 公開日 | 1998-04-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
|
|
1A9V
 | |
1NEP
 | | Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epididymal secretory protein E1, PHOSPHATE ION | | 著者 | Friedland, N, Liou, H.-L, Lobel, P, Stock, A.M. | | 登録日 | 2002-12-11 | | 公開日 | 2003-01-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of a Cholesterol-binding Protein Deficient in Niemann-Pick Type C2 Disease
Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
3M7O
 | | Crystal structure of mouse MD-1 in complex with phosphatidylcholine | | 分子名称: | (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... | | 著者 | Harada, H, Ohto, U, Satow, Y. | | 登録日 | 2010-03-17 | | 公開日 | 2010-06-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of mouse MD-1 with endogenous phospholipid bound in its cavity
J.Mol.Biol., 400, 2010
|
|
3MTX
 | | Crystal structure of chicken MD-1 | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, GLYCEROL, Protein MD-1, ... | | 著者 | Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A. | | 登録日 | 2010-05-01 | | 公開日 | 2010-06-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3MU3
 | | Crystal structure of chicken MD-1 complexed with lipid IVa | | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A. | | 登録日 | 2010-05-01 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
1PU5
 | |
1PUB
 | |
2E59
 | | Crystal structure of human MD-2 in complex with lipid IVa | | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, ... | | 著者 | Ohto, U, Satow, Y. | | 登録日 | 2006-12-19 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
Science, 316, 2007
|
|
2E56
 | | Crystal structure of human MD-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, MYRISTIC ACID | | 著者 | Ohto, U, Satow, Y. | | 登録日 | 2006-12-19 | | 公開日 | 2007-06-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316, 2007
|
|
2F08
 | | Crystal structure of a major house dust mite allergen, Derf 2 | | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, mite allergen Der f II | | 著者 | Mikami, B, Tanaka, Y, Minato, N, Suzuki, M, Korematsu, S. | | 登録日 | 2005-11-12 | | 公開日 | 2005-11-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure and some properties of a major house dust mite allergen, Derf 2
Biochem.Biophys.Res.Commun., 339, 2006
|
|
2HKA
 | | Crystal structure of bovine NPC2 and cholesterol sulfate complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... | | 著者 | Xu, S, Gu, L, Benoff, B, Stock, A.M. | | 登録日 | 2006-07-03 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease
J.Biol.Chem., 282, 2007
|
|
1XWV
 | | Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross-reactivity | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Der f II | | 著者 | Johannessen, B.R, Skov, L.K, Kastrup, J.S, Kristensen, O, Bolwig, C, Larsen, J.N, Spangfort, M, Lund, K, Gajhede, M. | | 登録日 | 2004-11-02 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity.
Febs Lett., 579, 2005
|
|
