PDB: 92 件ウェブページステータス検索Chemie searchBIRD

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7UW6	The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2 分子名称: 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.Y. 登録日 2022-05-02 公開日 2022-10-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J.Med.Chem., 65, 2022
6U1P	Crystal structure of VpsU (VC0916) from Vibrio cholerae 分子名称: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase 著者 Tripathi, S.M, Schwechheimer, C, Herbert, K, Osorio, J, Yildiz, F.H, Rubin, S.M. 登録日 2019-08-16 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae. Plos Pathog., 16, 2020
5Z3M	Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from Vibrio choleraeO395 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Phosphotyrosine protein phosphatase, ... 著者 Chatterjee, S, Nath, S, Sen, U. 登録日 2018-01-08 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Vibrio cholerae LMWPTP-2 display unique surface charge and grooves around the active site: Indicative of distinctive substrate specificity and scope to design specific inhibitor. Biochim Biophys Acta Proteins Proteom, 1867, 2019
5PNT	CRYSTAL STRUCTURE OF A HUMAN LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE. IMPLICATIONS FOR SUBSTRATE SPECIFICITY 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE 著者 Zhang, M, Stauffacher, C, Lin, D, Vanetten, R. 登録日 1998-04-29 公開日 1998-10-14 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity. J.Biol.Chem., 273, 1998
1C0E	Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase 分子名称: PHOSPHATE ION, PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE)) 著者 Tabernero, L, Evans, B.N, Tishmack, P.A, Van Etten, R.L, Stauffacher, C.V. 登録日 1999-07-15 公開日 1999-09-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism. Biochemistry, 38, 1999
7KH8	Human LMPTP in complex with inhibitor 分子名称: 3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine, Low molecular weight phosphotyrosine protein phosphatase, NITRATE ION 著者 Stanford, S.M, Diaz, M.A, Ardecky, R.J, Zou, J, Roosild, T, Holmes, Z.J, Hedrick, M.P, Rodiles, S, Santelli, E, Chung, T.D.Y, Jackson, M.R, Bottini, N, Pinkerton, A.B. 登録日 2020-10-20 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase. J.Med.Chem., 64, 2021
5GOT	Crystal structure of SP-PTP, low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes 分子名称: CHLORIDE ION, Low molecular weight phosphotyrosine phosphatase family protein 著者 Ku, B, Keum, C.W, KIim, S.J. 登録日 2016-07-29 公開日 2016-09-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes Biochem.Biophys.Res.Commun., 478, 2016
5O7B	CRYSTAL STRUCTURE OF THE SLR0328 TYROSINE PHOSPHATASE WZB FROM SYNECHOCYSTIS SP. PCC 6803 分子名称: Putative low molecular weight protein-tyrosine-phosphatase slr0328 著者 Leite, J.P, Gales, L. 登録日 2017-06-08 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803. Microbiologyopen, 2019
4LRQ	Crystal structure of a Low Molecular Weight Phosphotyrosine phosphatase from Vibrio choleraeO395 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Phosphotyrosine protein phosphatase, SULFATE ION 著者 Nath, S, Banerjee, R, Sen, U. 登録日 2013-07-20 公開日 2014-07-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Atomic resolution crystal structure of VcLMWPTP-1 from Vibrio cholerae O395: insights into a novel mode of dimerization in the low molecular weight protein tyrosine phosphatase family. Biochem.Biophys.Res.Commun., 450, 2014
2MYU	An arsenate reductase in oxidized state 分子名称: Glutaredoxin arsenate reductase 著者 Jin, C, Hu, C, Hu, Y. 登録日 2015-01-30 公開日 2015-08-05 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction. J.Biol.Chem., 290, 2015
6Y2V	Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) 分子名称: Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, TRIETHYLENE GLYCOL 著者 Levy, C. 登録日 2020-02-17 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme. Plos One, 15, 2020
6Y2W	Crystal structure of the single mutant I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) 分子名称: ACETATE ION, Low molecular weight phosphotyrosine protein phosphatase 著者 Levy, C. 登録日 2020-02-17 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme. Plos One, 15, 2020
2WMY	Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with sulphate. 分子名称: NICKEL (II) ION, PUTATIVE ACID PHOSPHATASE WZB, SULFATE ION 著者 Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H. 登録日 2009-07-03 公開日 2009-07-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.211 Å) 主引用文献 Crystal Structures of the Capsular Export Regulating Tyrosine Phosphatases Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae. To be Published
2WJA	Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with phosphate. 分子名称: NICKEL (II) ION, PHOSPHATE ION, PUTATIVE ACID PHOSPHATASE WZB 著者 Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H. 登録日 2009-05-25 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly. J.Mol.Biol., 392, 2009
2P4U	Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus 分子名称: Acid phosphatase 1, PHOSPHATE ION 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-03-13 公開日 2007-03-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
8P6M	Arsenate reductase (ArsC2) from Deinococcus indicus 分子名称: Low molecular weight phosphatase family protein 著者 Gouveia, A.G, Matias, P.M, Romao, C.V. 登録日 2023-05-26 公開日 2023-08-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus . Front Microbiol, 14, 2023
8P5N	Arsenate reductase (ArsC2) from Deinococcus indicus, co-crystallized with arsenate 分子名称: ARSENATE, GLYCEROL, Low molecular weight phosphatase family protein 著者 Gouveia, A.G, Matias, P.M, Romao, C.V. 登録日 2023-05-24 公開日 2023-08-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus . Front Microbiol, 14, 2023
4PIC	YwlE arginine phosphatase from Geobacillus stearothermophilus 分子名称: Arginine phosphatase Ywle, PHOSPHATE ION, SULFATE ION 著者 Clausen, T, Fuhrmann, J. 登録日 2014-05-08 公開日 2014-05-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap. Mol.Cell Proteomics, 2014
4KK3	YwlE arginine phosphatase - wildtype 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
4KK4	YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
3N8I	Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid 分子名称: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID 著者 Homan, K.T, Balasubramaniam, D, Stauffacher, C.V. 登録日 2010-05-28 公開日 2011-12-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases To be Published
4Z99	Crystal structure of the apo Low Molecular Weight Protein Tyrosine Phosphatase isoform A 分子名称: Low molecular weight phosphotyrosine protein phosphatase 著者 Fonseca, E.M.B, Scorsato, V, Dias, M.P, de Oliveria, F.L, Miranda, P.C.M.L, Aparicio, R. 登録日 2015-04-10 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23, 2015
4Z9B	Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with benzylphosphonic acid 分子名称: Low molecular weight phosphotyrosine protein phosphatase, benzylphosphonic acid 著者 Fonseca, E.M.B, Trivella, D.B.B, Scorsato, V, Dias, M.P, de Oliveira, F.L, Miranda, P.C.M.L, Aparicio, R. 登録日 2015-04-10 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23, 2015
4Z9A	Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with phenylmethanesulfonic acid 分子名称: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION, ... 著者 Trivella, D.B.B, Fonseca, E.M.B, Scorsato, V, Dias, M.P, Aparicio, R. 登録日 2015-04-10 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23, 2015
3RH0	Corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate reductase Cg_ArsC2 分子名称: ARSENATE REDUCTASE 著者 Messens, J, Wahni, K, Dufe, T.V. 登録日 2011-04-11 公開日 2011-11-30 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.724 Å) 主引用文献 Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms Mol.Microbiol., 82, 2011

 

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