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4QN0
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Crystal structure of the CPS-6 mutant Q130K
分子名称: Endonuclease G, mitochondrial, MAGNESIUM ION
著者Lin, J.L.J, Yuan, H.S.
登録日2014-06-17
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
Cell Rep, 16, 2016
1ZM8
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Apo Crystal structure of Nuclease A from Anabaena sp.
分子名称: MANGANESE (II) ION, Nuclease, SODIUM ION, ...
著者Ghosh, M, Meiss, G, Pingoud, A, London, R.E, Pedersen, L.C.
登録日2005-05-10
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Mechanism of Nuclease A, a beta beta alpha Metal Nuclease from Anabaena.
J.Biol.Chem., 280, 2005
1G8T
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BU of 1g8t by Molmil
SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT 1.1 A RESOLUTION
分子名称: MAGNESIUM ION, NUCLEASE SM2 ISOFORM, SULFATE ION
著者Lunin, V.V, Perbandt, M, Betzel, C.H, Mikhailov, A.M.
登録日2000-11-21
公開日2000-12-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism.
Acta Crystallogr.,Sect.D, 56, 2000
1QAE
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BU of 1qae by Molmil
THE ACTIVE SITE OF SERRATIA ENDONUCLEASE CONTAINS A CONSERVED MAGNESIUM-WATER CLUSTER
分子名称: MAGNESIUM ION, PROTEIN (EXTRACELLULAR ENDONUCLEASE)
著者Miller, M.D, Krause, K.L.
登録日1999-03-03
公開日1999-05-18
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The active site of Serratia endonuclease contains a conserved magnesium-water cluster.
J.Mol.Biol., 288, 1999
1QL0
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BU of 1ql0 by Molmil
Sm Endonuclease from Seratia marcenscens at atomic resolution
分子名称: MAGNESIUM ION, NUCLEASE
著者Perbandt, M, Mikhailov, A.M, Betzel, C.H.
登録日1999-08-18
公開日2000-05-07
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic Structure of the Serratia Marcescens Endonuclease at 1.1 A Resolution and the Enzyme Reaction Mechanism.
Acta Crystallogr.,Sect.D, 56, 2000
4E3Y
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BU of 4e3y by Molmil
X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Lashkov, A.A, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M.
登録日2012-03-11
公開日2013-05-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution
To be Published
1SMN
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BU of 1smn by Molmil
IDENTIFICATION OF THE SERRATIA ENDONUCLEASE DIMER: STRUCTURAL BASIS AND IMPLICATIONS FOR CATALYSIS
分子名称: EXTRACELLULAR ENDONUCLEASE
著者Miller, M.D, Krause, K.L.
登録日1995-01-25
公開日1996-01-29
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Identification of the Serratia endonuclease dimer: structural basis and implications for catalysis.
Protein Sci., 5, 1996
3S5B
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BU of 3s5b by Molmil
Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans
分子名称: Endonuclease G, MAGNESIUM ION
著者Yuan, H.S, Lin, J.L.J.
登録日2011-05-23
公開日2012-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans
J.Biol.Chem., 287, 2012
5FGW
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BU of 5fgw by Molmil
Structure of Sda1 nuclease with bound zinc ion
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Moon, A.F, Krahn, J.M, Xun, L, Cuneo, M.J, Pedersen, L.C.
登録日2015-12-21
公開日2016-03-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.
Nucleic Acids Res., 44, 2016
6M3T
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BU of 6m3t by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P41212
分子名称: Endonuclease G, mitochondrial, MAGNESIUM ION
著者Park, K.H, Woo, E.J.
登録日2020-03-04
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6LYF
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BU of 6lyf by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/Se-Met)
分子名称: Endonuclease G, mitochondrial, MAGNESIUM ION
著者Park, K.H, Woo, E.J.
登録日2020-02-14
公開日2020-08-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6M3F
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BU of 6m3f by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121
分子名称: Endonuclease G, mitochondrial, MAGNESIUM ION
著者Park, K.H, Woo, E.J.
登録日2020-03-03
公開日2020-08-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of the mouse endonuclease G.
Biochem.Biophys.Res.Commun., 526, 2020
6M3U
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BU of 6m3u by Molmil
Crystal structure of the mouse endonuclease EndoG(H138A/C100A), space group C2
分子名称: Endonuclease G, mitochondrial
著者Park, K.H, Woo, E.J.
登録日2020-03-04
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure of the mouse endonuclease EndoG(H138A/C100A), space group C2
To Be Published
3OWV
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BU of 3owv by Molmil
Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae
分子名称: CHLORIDE ION, DNA-entry nuclease, MAGNESIUM ION
著者Moon, A.F, Midon, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
登録日2010-09-20
公開日2010-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
Nucleic Acids Res., 39, 2011
6NJT
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BU of 6njt by Molmil
Mouse endonuclease G mutant - H97A
分子名称: CHLORIDE ION, Endonuclease G, mitochondrial, ...
著者Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S.
登録日2019-01-04
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.
Nucleic Acids Res., 48, 2020
6NJU
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BU of 6nju by Molmil
Mouse endonuclease G mutant H97A bound to A-DNA
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DNA (5'-D(CCGGCGCCGG)-3'), ...
著者Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S.
登録日2019-01-04
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.
Nucleic Acids Res., 48, 2020
5GKP
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BU of 5gkp by Molmil
Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA
分子名称: DNA (5'-D(*TP*TP*TP*TP*T)-3'), Endonuclease G, mitochondrial, ...
著者Lin, J.L, Yuan, H.S.
登録日2016-07-05
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
5GKC
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BU of 5gkc by Molmil
The crystal structure of the CPS-6 H148A/F122A
分子名称: Endonuclease G, mitochondrial
著者Lin, J.L, Yuan, H.S.
登録日2016-07-04
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
8GHR
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BU of 8ghr by Molmil
Structure of human ENPP1 in complex with variable heavy domain VH27.2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
著者Carozza, J.A, Wang, H, Solomon, P.E, Wells, J.A, Li, L.
登録日2023-03-10
公開日2023-08-02
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Discovery of VH domains that allosterically inhibit ENPP1.
Nat.Chem.Biol., 20, 2024
2O3B
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BU of 2o3b by Molmil
Crystal structure complex of Nuclease A (NucA) with intra-cellular inhibitor NuiA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ...
著者Ghosh, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
登録日2006-12-01
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.
J.Biol.Chem., 282, 2007
6IID
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BU of 6iid by Molmil
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
分子名称: DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ...
著者Wu, C.C, Lin, J.L.J, Yuan, H.S.
登録日2018-10-04
公開日2019-04-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.986 Å)
主引用文献A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
3ISM
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BU of 3ism by Molmil
Crystal structure of the EndoG/EndoGI complex: Mechanism of EndoG inhibition
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CG4930, CG8862, ...
著者Loll, B, Gebhardt, M, Wahle, E, Meinhart, A.
登録日2009-08-26
公開日2009-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
Nucleic Acids Res., 37, 2009
7R6V
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BU of 7r6v by Molmil
Human EXOG complexed with dRP-containing DNA
分子名称: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*AP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*CP*G)-3'), MAGNESIUM ION, ...
著者Szymanski, M.R, Yin, Y.W.
登録日2021-06-23
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human EXOG possesses strong AP hydrolysis activity
To Be Published
7R6T
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Human EXOG complexed with dRP-containing DNA
分子名称: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*A)-3'), DNA (5'-D(3DR)P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), MAGNESIUM ION, ...
著者Szymanski, M.R, Yin, Y.W.
登録日2021-06-23
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human EXOG possesses strong AP hydrolysis activity
To Be Published
4A1N
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Human Mitochondrial endo-exonuclease
分子名称: CHLORIDE ION, MAGNESIUM ION, NUCLEASE EXOG, ...
著者Welin, M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Nyman, T, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, Weigelt, J, Nordlund, P.
登録日2011-09-16
公開日2012-02-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Mitochondrial Endo-Exonuclease
To be Published

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