Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5T1J
DownloadVisualize
BU of 5t1j by Molmil
Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet
分子名称: DNA, T-box transcription factor TBX21
著者Liu, C.F, Brandt, G.S, Hoang, Q, Hwang, E.S, Naumova, N, Lazarevic, V, Dekker, J, Glimcher, L.H, Ringe, D, Petsko, G.A.
登録日2016-08-19
公開日2016-10-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.947 Å)
主引用文献Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.
Proc.Natl.Acad.Sci.USA, 113, 2016
6ZU8
DownloadVisualize
BU of 6zu8 by Molmil
Crystal structure of human Brachyury G177D variant in complex with Afatinib
分子名称: Brachyury protein, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide, ZINC ION
著者Newman, J.A, Gavard, A.E, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2020-07-21
公開日2020-08-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human Brachyury G177D variant in complex with Afatinib
To Be Published
4A04
DownloadVisualize
BU of 4a04 by Molmil
Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome
分子名称: DNA, T-BOX TRANSCRIPTION FACTOR TBX1
著者El Omari, K, De Mesmaeker, J, Karia, D, Ginn, H, Bhattacharya, S, Mancini, E.J.
登録日2011-09-07
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure of the DNA-Bound T-Box Domain of Human Tbx1, a Transcription Factor Associated with the Digeorge Syndrome
Proteins, 80, 2012
8FMU
DownloadVisualize
BU of 8fmu by Molmil
Crystal structure of human Brachyury G177D variant in complex with SJF-4601
分子名称: N-(3-chloro-4-fluorophenyl)-3-[4-(dimethylamino)butanamido]-4-methoxybenzamide, T-box transcription factor T
著者Bebenek, A, Linhares, B, Jaime-Figueroa, S, Butrin, A, Crews, C.
登録日2022-12-24
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Discovery and Development of the First Selective Brachyury Degrader
To Be Published
8CDN
DownloadVisualize
BU of 8cdn by Molmil
Crystal structure of human Brachyury in complex with a single T box binding element DNA
分子名称: DNA (5'-D(*AP*GP*GP*CP*TP*CP*AP*CP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*GP*TP*GP*AP*GP*CP*CP*T)-3'), T-box transcription factor T
著者Newman, J.A, Gavard, A.E, von Delft, F, Gileadi, O, Bountra, C.
登録日2023-01-31
公開日2023-03-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human Brachyury in complex with a single T box binding element DNA
To Be Published
1H6F
DownloadVisualize
BU of 1h6f by Molmil
Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
分子名称: 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX3
著者Coll, M, Muller, C.W.
登録日2001-06-13
公開日2002-04-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10, 2002
1XBR
DownloadVisualize
BU of 1xbr by Molmil
T DOMAIN FROM XENOPUS LAEVIS BOUND TO DNA
分子名称: DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*G P*TP*GP*AP*AP*AP* TP*T)-3'), PROTEIN (T PROTEIN)
著者Muller, C.W.
登録日1997-07-16
公開日1998-01-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
Nature, 389, 1997
5BQD
DownloadVisualize
BU of 5bqd by Molmil
Crystal Structure of TBX5 (1-239) Dimer
分子名称: MAGNESIUM ION, T-box transcription factor TBX5
著者Pradhan, L, Gopal, S, Patel, A, Kasahara, H, Nam, H.J.
登録日2015-05-28
公開日2016-03-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.583 Å)
主引用文献Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
8A10
DownloadVisualize
BU of 8a10 by Molmil
Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143
分子名称: T-box transcription factor T, UNKNOWN LIGAND
著者Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O.
登録日2022-05-30
公開日2022-07-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143
To Be Published
8A7N
DownloadVisualize
BU of 8a7n by Molmil
Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125)
分子名称: N-(3-azanylpropyl)-3-[[(3S)-1-(2-fluorophenyl)-2-oxidanylidene-pyrrolidin-3-yl]amino]-N-methyl-benzamide, PHOSPHATE ION, T-box transcription factor T
著者Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O.
登録日2022-06-21
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125)
To Be Published
2X6U
DownloadVisualize
BU of 2x6u by Molmil
Crystal structure of human TBX5 in the DNA-free form
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5
著者Stirnimann, C.U, Mueller, C.W.
登録日2010-02-22
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
2X6V
DownloadVisualize
BU of 2x6v by Molmil
Crystal structure of human TBX5 in the DNA-bound and DNA-free form
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3', ...
著者Ptchelkine, D, Stirnimann, C.U, Grimm, C, Mueller, C.W.
登録日2010-02-22
公開日2010-04-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
6F59
DownloadVisualize
BU of 6f59 by Molmil
Crystal structure of human Brachyury (T) G177D variant in complex with DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Brachyury protein, DNA (26-MER), ...
著者Newman, J.A, Gavard, A.E, Krojer, T, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2017-12-01
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Crystal structure of human Brachyury (T) G177D variant in complex with DNA
To Be Published
6F58
DownloadVisualize
BU of 6f58 by Molmil
Crystal structure of human Brachyury (T) in complex with DNA
分子名称: Brachyury protein, DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*TP*T)-3'), SODIUM ION
著者Newman, J.A, Gavard, A.E, Krojer, T, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2017-12-01
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.253 Å)
主引用文献Crystal structure of human Brachyury (T) in complex with DNA
To Be Published
7ZK2
DownloadVisualize
BU of 7zk2 by Molmil
Crystal Structure of human Brachyury G177D variant in complex with CSC027898502
分子名称: N-[4-(2-morpholin-4-yl-1,3-thiazol-4-yl)phenyl]ethanamide, PHOSPHATE ION, T-box transcription factor T
著者Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O.
登録日2022-04-12
公開日2022-06-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of human Brachyury G177D variant in complex with CSC027898502
To Be Published
7ZL2
DownloadVisualize
BU of 7zl2 by Molmil
Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810
分子名称: T-box transcription factor T, UNKNOWN LIGAND
著者Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O.
登録日2022-04-13
公開日2022-06-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810
To Be Published
7ZKF
DownloadVisualize
BU of 7zkf by Molmil
Crystal Structure of human Brachyury G177D variant in complex with CF-5-86
分子名称: PHOSPHATE ION, T-box transcription factor T, UNKNOWN LIGAND
著者Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O.
登録日2022-04-12
公開日2022-06-22
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Crystal Structure of human Brachyury G177D variant in complex with CF-5-86
To Be Published
5QSL
DownloadVisualize
BU of 5qsl by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1273312153
分子名称: CADMIUM ION, N-methyl-1H-indole-7-carboxamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-07-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QRH
DownloadVisualize
BU of 5qrh by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z32327641
分子名称: CADMIUM ION, T-box transcription factor T, [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone
著者Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-07-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QS6
DownloadVisualize
BU of 5qs6 by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z44592329
分子名称: N-phenyl-N'-pyridin-3-ylurea, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Fernandez-Cid, A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-06-19
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QSK
DownloadVisualize
BU of 5qsk by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434906
分子名称: (benzyloxy)acetic acid, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QS7
DownloadVisualize
BU of 5qs7 by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z32327641
分子名称: T-box transcription factor T, [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QRM
DownloadVisualize
BU of 5qrm by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1899842917
分子名称: 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-5-methyl-1,3,4-thiadiazol-2(3H)-one, CADMIUM ION, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-07-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QSD
DownloadVisualize
BU of 5qsd by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z54571979
分子名称: N-{4-[(pyrimidin-2-yl)oxy]phenyl}acetamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QRI
DownloadVisualize
BU of 5qri by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434826
分子名称: CADMIUM ION, T-box transcription factor T, [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone
著者Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-07-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献PanDDA analysis group deposition
To Be Published

 

123>

217705

件を2024-03-27に公開中

PDB statisticsPDBj update infoContact PDBjnumon