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7RNN
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BU of 7rnn by Molmil
Human ASIC1a-Nb.C1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Nanobodies Nb.C1
著者Wu, Y, Chen, Z, Sigworth, F.J, Canessa, C.M.
登録日2021-07-29
公開日2021-08-11
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structure and analysis of nanobody binding to the human ASIC1a ion channel.
Elife, 10, 2021
6CMC
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BU of 6cmc by Molmil
Barium sites in the structure of a desensitized acid sensing ion channel
分子名称: Acid-sensing ion channel 1, CHLORIDE ION
著者Yoder, N, Gouaux, E.
登録日2018-03-03
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.671 Å)
主引用文献Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography.
PLoS ONE, 13, 2018
3IJ4
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BU of 3ij4 by Molmil
Cesium sites in the crystal structure of a functional acid sensing ion channel in the desensitized state
分子名称: Amiloride-sensitive cation channel 2, neuronal, CESIUM ION, ...
著者Gonzales, E.B, Gouaux, E.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.
Nature, 460, 2009
6VTL
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BU of 6vtl by Molmil
Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a resting state at high pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1
著者Yoder, N, Gouaux, E.
登録日2020-02-12
公開日2020-03-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity.
Elife, 9, 2020
2QTS
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BU of 2qts by Molmil
Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ...
著者Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E.
登録日2007-08-02
公開日2007-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Nature, 449, 2007
3S3X
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BU of 3s3x by Molmil
Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, neuronal, ...
著者Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A.
登録日2011-05-18
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.
Nat Commun, 3, 2012
3S3W
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Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, ...
著者Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A.
登録日2011-05-18
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.
Nat Commun, 3, 2012
4FZ1
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Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at high pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Pi-theraphotoxin-Pc1a
著者Baconguis, I, Gouaux, E.
登録日2012-07-05
公開日2012-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.359 Å)
主引用文献Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes.
Nature, 489, 2012
4FZ0
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Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at low pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHLORIDE ION, ...
著者Baconguis, I, Gouaux, E.
登録日2012-07-05
公開日2012-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes.
Nature, 489, 2012
7CFS
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BU of 7cfs by Molmil
Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHOLESTEROL HEMISUCCINATE, ...
著者Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L.
登録日2020-06-28
公開日2020-10-21
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
Elife, 9, 2020
7CFT
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BU of 7cft by Molmil
Cryo-EM strucutre of human acid-sensing ion channel 1a in complex with snake toxin Mambalgin1 at pH 8.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Mambalgin-1
著者Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L.
登録日2020-06-28
公開日2020-10-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
Elife, 9, 2020
5WKV
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BU of 5wkv by Molmil
Structure of an acid sensing ion channel in a resting state with calcium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Gating mechanisms of acid-sensing ion channels.
Nature, 555, 2018
5WKY
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BU of 5wky by Molmil
Bromide sites in the structure of an acid sensing ion channel in a resting state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography.
PLoS ONE, 13, 2018
7YVB
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BU of 7yvb by Molmil
Aplysia californica FaNaC in ligand bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated Na+ channel, ...
著者Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
登録日2022-08-19
公開日2023-08-09
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
7YVC
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BU of 7yvc by Molmil
Aplysia californica FaNaC in apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
登録日2022-08-19
公開日2023-08-09
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
6VTK
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BU of 6vtk by Molmil
Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1
著者Yoder, N, Gouaux, E.
登録日2020-02-12
公開日2020-03-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity.
Elife, 9, 2020
6WTH
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BU of 6wth by Molmil
Full-length human ENaC ECD
分子名称: 10D4 Fab, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Posert, R, Baconguis, I, Noreng, S, Bharadwaj, A, Houser, A.
登録日2020-05-02
公開日2020-08-12
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Molecular principles of assembly, activation, and inhibition in epithelial sodium channel.
Elife, 9, 2020
6X9H
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BU of 6x9h by Molmil
Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1)
分子名称: 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1.
Commun Biol, 4, 2021
6L6I
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BU of 6l6i by Molmil
hASIC1a co-crystallized with Mamb-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1
著者Lei, F, Jian, S.
登録日2019-10-29
公開日2020-11-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献hASIC1a co-crystallized with Mamb-1
To Be Published
6L6N
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BU of 6l6n by Molmil
hASIC1a co-crystallized with Nafamostat
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lei, F, Jian, S.
登録日2019-10-29
公開日2021-01-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献hASIC1a co-crystallized with Mamb-1
To Be Published
6L6P
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BU of 6l6p by Molmil
hASIC2a co-crystallized with Mamb-1
分子名称: Acid-sensing ion channel 2
著者Lei, F, Jian, S.
登録日2019-10-29
公開日2020-11-04
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献hASIC2a co-crystallized with Mamb-1
To Be Published
5WKU
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BU of 5wku by Molmil
Structure of an acid sensing ion channel in a resting state with barium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Gating mechanisms of acid-sensing ion channels.
Nature, 555, 2018
5WKX
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BU of 5wkx by Molmil
Barium sites in the structure of a resting acid sensing ion channel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.034 Å)
主引用文献Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography.
PLoS ONE, 13, 2018
4NYK
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BU of 4nyk by Molmil
Structure of a membrane protein
分子名称: Acid-sensing ion channel 1, CHLORIDE ION
著者Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
登録日2013-12-10
公開日2014-02-12
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.
Nature, 460, 2009
6AVE
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BU of 6ave by Molmil
Structure of an acid sensing ion channel in a resting state at high pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1
著者Yoder, N, Yoshioka, C, Gouaux, E.
登録日2017-09-02
公開日2018-03-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Gating mechanisms of acid-sensing ion channels.
Nature, 555, 2018

 

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