7EZN
| |
4WOH
| Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate | 分子名称: | 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S. | 登録日 | 2014-10-15 | 公開日 | 2015-02-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate. Acta Crystallogr.,Sect.F, 71, 2015
|
|
7C8S
| Crystal structure of DUSP22 mutant_N128A | 分子名称: | Dual specificity protein phosphatase 22, SULFATE ION | 著者 | Lai, C.H, Lyu, P.C. | 登録日 | 2020-06-03 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
|
|
7NCY
| Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3 | 分子名称: | Dual specificity phosphatase, GLYCEROL, NICKEL (II) ION | 著者 | Welin, M, Akutsu, M, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Nordberg Karlsson, E. | 登録日 | 2021-01-29 | 公開日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3 To Be Published
|
|
5GTJ
| |
3LJ8
| Crystal Structure of MKP-4 | 分子名称: | Tyrosine-protein phosphatase | 著者 | Jeong, D.G, Yoon, T.S, Jung, S.-K, Park, H.S, Ryu, S.E, Kim, S.J. | 登録日 | 2010-01-26 | 公開日 | 2010-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4 Acta Crystallogr.,Sect.D, 67, 2011
|
|
1I9S
| CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | 分子名称: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | 著者 | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | 登録日 | 2001-03-20 | 公開日 | 2001-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J., 20, 2001
|
|
4R30
| |
2WGP
| Crystal structure of human dual specificity phosphatase 14 | 分子名称: | DUAL SPECIFICITY PROTEIN PHOSPHATASE 14, PHOSPHATE ION | 著者 | Lountos, G.T, Tropea, J.E, Cherry, S, Waugh, D.S. | 登録日 | 2009-04-22 | 公開日 | 2009-10-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Overproduction, Purification and Structure Determination of Human Dual-Specificity Phosphatase 14. Acta Crystallogr.,Sect.D, 65, 2009
|
|
7U4O
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | 分子名称: | 3,3-dimethyl-1-{[(9aM)-9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, Dual specificity protein phosphatase 10 | 著者 | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | 登録日 | 2022-02-28 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
|
|
7U4R
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | 分子名称: | 3,3-dimethyl-1-{[(9aM)-9-propyl-5,6-dihydrothieno[2,3-h]quinazolin-2-yl]sulfanyl}butan-2-one, Dual specificity protein phosphatase 10 | 著者 | Gannam, Z.T.K, Jamali, H, Gentzel, E, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | 登録日 | 2022-02-28 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. Eur.J.Med.Chem., 243, 2022
|
|
2Y96
| |
4MBB
| Cubic crystal form of PIR1 dual specificity phosphatase core | 分子名称: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | 著者 | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | 登録日 | 2013-08-19 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase. Biochemistry, 53, 2014
|
|
4Y2E
| Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S) | 分子名称: | Dual specificity protein phosphatase 7, PHOSPHATE ION | 著者 | Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S. | 登録日 | 2015-02-09 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structure of human dual-specificity phosphatase 7, a potential cancer drug target. Acta Crystallogr.,Sect.F, 71, 2015
|
|
2C46
| CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase | 分子名称: | MRNA CAPPING ENZYME | 著者 | Debreczeni, J, Johansson, C, Longman, E, Gileadi, O, SavitskySmee, P, Smee, C, Bunkoczi, G, Ugochukwu, E, von Delft, F, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | 登録日 | 2005-10-15 | 公開日 | 2005-11-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase To be Published
|
|
4NYH
| Orthorhombic crystal form of pir1 dual specificity phosphatase core | 分子名称: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | 著者 | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | 登録日 | 2013-12-10 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase. Biochemistry, 53, 2014
|
|
5BX1
| |
2E0T
| Crystal structure of catalytic domain of dual specificity phosphatase 26, MS0830 from Homo sapiens | 分子名称: | Dual specificity phosphatase 26 | 著者 | Xie, Y, Kishishita, S, Murayama, K, Hori-Takemoto, C, Chen, L, Liu, Z.J, Wang, B.C, Shirozu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-10-13 | 公開日 | 2007-10-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | High-resolution crystal structure of the catalytic domain of human dual-specificity phosphatase 26. Acta Crystallogr.,Sect.D, 69, 2013
|
|
2ESB
| Crystal structure of human DUSP18 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Dual specificity protein phosphatase 18 | 著者 | Kim, S.J, Ryu, S.E, Jeong, D.G, Cho, Y.H, Yoon, T.S, Kim, J.H. | 登録日 | 2005-10-25 | 公開日 | 2006-06-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family. Acta Crystallogr.,Sect.D, 62, 2006
|
|
1I9T
| CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | 分子名称: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | 著者 | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | 登録日 | 2001-03-20 | 公開日 | 2001-05-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J., 20, 2001
|
|
1J4X
| HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX | 分子名称: | DDE(AHP)(TPO)G(PTR)VATR, DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 | 著者 | Schumacher, M.A, Todd, J.L, Tanner, K.G, Denu, J.M. | 登録日 | 2001-12-13 | 公開日 | 2001-12-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase. Biochemistry, 41, 2002
|
|
5M43
| |
3CM3
| |
5NCR
| OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity | 分子名称: | PHOSPHATE ION, SULFATE ION, tyrosine phosphatase | 著者 | Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. | 登録日 | 2017-03-06 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity. J. Mol. Biol., 429, 2017
|
|
3EMU
| Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica | 分子名称: | SULFATE ION, leucine rich repeat and phosphatase domain containing protein | 著者 | Bonanno, J.B, Gilmore, M, Bain, K.T, Hu, S, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-09-25 | 公開日 | 2008-10-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica To be Published
|
|