PDB: 256 件ウェブページステータス検索Chemie searchBIRD

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1HL2	Crystal structure of N-acetylneuraminate lyase from E. coli mutant L142R in complex with b-hydroxypyruvate 分子名称: 3-HYDROXYPYRUVIC ACID, N-ACETYLNEURAMINATE LYASE SUBUNIT 著者 Joerger, A.C, Fersht, A.R. 登録日 2003-03-12 公開日 2003-05-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mimicking Natural Evolution in Vitro: An N-Acetylneuraminate Lyase Mutant with an Increased Dihydrodipicolinate Synthase Activity Proc.Natl.Acad.Sci.USA, 100, 2003
8GEK	Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 著者 Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. 登録日 2023-03-06 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum To Be Published
2HMC	The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens 分子名称: Dihydrodipicolinate synthase, MAGNESIUM ION 著者 Kim, Y, Zhang, R, Xu, X, Zheng, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-07-11 公開日 2006-09-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens To be Published, 2006
8DO5	Crystal structure of NahE in complex with intermediate (R)-4-hydroxy-4-(2-hydroxyphenyl)-2-iminobutanoate 分子名称: (4R)-4-hydroxy-4-(2-hydroxyphenyl)butanoic acid, DIMETHYL SULFOXIDE, Trans-ohydrobenzylidenepyruvate hydratase aldolase 著者 LeVieux, J.A, Hardtke, H.A, Zhang, Y.J. 登録日 2022-07-12 公開日 2022-12-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway. Arch.Biochem.Biophys., 733, 2023
6MQH	Crystal structure of 4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) from Burkholderia mallei 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-10-09 公開日 2018-10-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of 4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) from Burkholderia mallei To be Published
6NVA	Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound to K161. 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, SODIUM ION 著者 Thomas, L.M, Chooback, L. 登録日 2019-02-04 公開日 2019-02-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound to K161. To Be Published
4R53	dihydrodipicolinate synthase from C. jejuni with vacant active site and vacant allosteric site 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, ... 著者 Conly, C.J.T. 登録日 2014-08-20 公開日 2015-10-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine. Biochemistry, 53, 2014
6P90	Crystal structure of PaDHDPS2-H56Q mutant 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL 著者 Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P. 登録日 2019-06-08 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation. Febs J., 287, 2020
4U4M	Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate 分子名称: 1,2-ETHANEDIOL, PYRUVIC ACID, UREA, ... 著者 Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S. 登録日 2014-07-24 公開日 2015-07-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate To be published
7M06	Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with R,R-bislysine bound at the allosteric site at 2.7 Angstrom 分子名称: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... 著者 Saran, S, Sanders, D.A.R. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS To Be Published
7MJF	Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site 分子名称: (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase 著者 Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J. 登録日 2021-04-20 公開日 2021-07-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site To Be Published
7MDS	Crystal structure of AtDHDPS1 in complex with MBDTA-2 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... 著者 Hall, C.J, Soares da Costa, T.P, Panjikar, S. 登録日 2021-04-06 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10, 2021
5T25	Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, SODIUM ION 著者 Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. 登録日 2016-08-23 公開日 2017-03-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. To Be Published
7C0D	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (Hydroxypyruvate-bound form) 分子名称: L-2-keto-3-deoxyarabonate dehydratase 著者 Watanabe, Y, Watanabe, S. 登録日 2020-05-01 公開日 2020-08-05 最終更新日 2020-09-02 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
5T26	Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, L(+)-TARTARIC ACID, ... 著者 Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. 登録日 2016-08-23 公開日 2016-10-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. To Be Published
7C0E	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (2-oxobutyrate-bound form) 分子名称: L-2-keto-3-deoxyarabonate dehydratase 著者 Watanabe, Y, Ono, A, Watanabe, S. 登録日 2020-05-01 公開日 2020-08-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
4XKY	Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution 分子名称: ACETATE ION, Dihydrodipicolinate synthase, SODIUM ION 著者 Mank, N.J, Arnette, A.K, Klapper, V.G, Chruszcz, M. 登録日 2015-01-12 公開日 2015-04-01 最終更新日 2015-04-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 angstrom resolution. Acta Crystallogr.,Sect.F, 71, 2015
7C0C	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (apo form) 分子名称: L-2-keto-3-deoxyarabonate dehydratase 著者 Watanabe, Y, Nobuchi, R, Watanabe, S. 登録日 2020-05-01 公開日 2020-08-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
5ZJM	Crystal structure of N-acetylneuraminate lyase from Fusobacterium nucleatum 分子名称: 1,2-ETHANEDIOL, N-acetylneuraminate lyase 著者 Kumar, J.P, Rao, H, Nayak, V, Subramanian, R. 登録日 2018-03-21 公開日 2019-01-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.323 Å) 主引用文献 Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum Acta Crystallogr F Struct Biol Commun, 74, 2018
5ZKA	Crystal structure of N-acetylneuraminate lyase from Fusobacterium nucleatum complexed with Pyruvate 分子名称: 1,2-ETHANEDIOL, N-acetylneuraminate lyase, TRIETHYLENE GLYCOL 著者 Kumar, J.P, Rao, H, Nayak, V, Ramaswamy, S. 登録日 2018-03-23 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum Acta Crystallogr F Struct Biol Commun, 74, 2018
5UD6	Crystal structure of DHDPS from Cyanidioschyzon merolae with lysine bound 分子名称: CALCIUM ION, Dihydrodipicolinate synthase, LYSINE 著者 Watkin, S, Keown, J.R, Pearce, F.G. 登録日 2016-12-23 公開日 2017-12-27 最終更新日 2018-12-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of DHDPS from Cyanidioschyzon merolae with lysine bound To Be Published
6ARH	Crystal structure of Human NAL at a resolution of 1.6 Angstrom 分子名称: ACETATE ION, N-acetylneuraminate lyase 著者 Pearce, F.G, Bundela, R, Keown, J.R. 登録日 2017-08-22 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Human NAL at a resolution of 1.6 Angstrom To Be Published
5AFD	Native structure of N-acetylneuramininate lyase (sialic acid aldolase) from Aliivibrio salmonicida 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-ACETYLNEURAMINATE LYASE 著者 Gurung, M.K, Altermark, B, Rader, I.L.U, Helland, R, Smalas, A.O. 登録日 2015-01-21 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Features and structure of a cold active N-acetylneuraminate lyase. Plos One, 14, 2019
5A8G	Crystal structure of the wild-type Staphylococcus aureus N- acetylneurminic acid lyase in complex with fluoropyruvate 分子名称: N-ACETYLNEURAMINATE LYASE 著者 Stockwell, J, Daniels, A.D, Windle, C.L, Harman, T, Woodhall, T, Trinh, C.H, Lebel, T, Pearson, A.R, Mulholland, K, Berry, A, Nelson, A. 登録日 2015-07-15 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Evaluation of Fluoropyruvate as Nucleophile in Reactions Catalysed by N-Acetyl Neuraminic Acid Lyase Variants: Scope, Limitations and Stereoselectivity. Org.Biomol.Chem., 14, 2016
5KZE	N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus 分子名称: GLYCEROL, N-acetylneuraminate lyase, SULFATE ION 著者 North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. 登録日 2016-07-25 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016

 

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