7RH2
 
 | | IRF4 Transcription factor mutant -K59R | | 分子名称: | DNA (5'-D(*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), ICSAT transcription factor | | 著者 | Williams, S.J, Sundararaj, S, Casarotto, M.G. | | 登録日 | 2021-07-16 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Protein Sci., 31, 2022
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7JM4
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2IRF
 | | CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX. | | 分子名称: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), INTERFERON REGULATORY FACTOR 2, ... | | 著者 | Fujii, Y, Shimizu, T, Kusumoto, M, Kyogoku, Y, Taniguchi, T, Hakoshima, T. | | 登録日 | 1999-05-30 | | 公開日 | 1999-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.
EMBO J., 18, 1999
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7O56
 | | X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods | | 分子名称: | DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP*GP*AP*AP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP*TP*CP*TP*TP*TP*TP*AP*T)-3'), Interferon regulatory factor 4 | | 著者 | El Omari, K, Agnarelli, A, Duman, R, Wagner, A, Mancini, E.J. | | 登録日 | 2021-04-07 | | 公開日 | 2021-05-12 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4.
Acta Crystallogr.,Sect.F, 77, 2021
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6TD4
 | | IRF4 DNA-binding domain surface entropy mutant apo structure | | 分子名称: | CHLORIDE ION, Interferon regulatory factor 4 | | 著者 | Tucker, J.A, Martin, M.P, Wang, L.Z, Jennings, C, Heath, R. | | 登録日 | 2019-11-07 | | 公開日 | 2020-11-18 | | 最終更新日 | 2021-06-23 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Cancer-associated mutations in the IRF4 DNA-binding domain confer no disadvantage in DNA-binding affinity and may increase transcriptional activity
To Be Published
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2DLL
 | | Solution structure of the IRF domain of human interferon regulator factors 4 | | 分子名称: | Interferon regulatory factor 4 | | 著者 | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-20 | | 公開日 | 2006-10-20 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the IRF domain of human interferon regulator factors 4
To be published
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7OGS
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7OOT
 | | X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element | | 分子名称: | DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), Interferon regulatory factor 4, ... | | 著者 | Agnarelli, A, El Omari, K, Alt, A.O, Mancini, E.J. | | 登録日 | 2021-05-28 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to interferon-stimulated response element
To Be Published
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4HLY
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4HLX
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3QU3
 | | Crystal structure of IRF-7 DBD apo form | | 分子名称: | 1,2-ETHANEDIOL, Interferon regulatory factor 7, SODIUM ION | | 著者 | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | | 登録日 | 2011-02-23 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
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3QU6
 | | Crystal structure of IRF-3 DBD free form | | 分子名称: | CHLORIDE ION, IRF3 protein, SODIUM ION, ... | | 著者 | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | | 登録日 | 2011-02-23 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
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2O6G
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1IRG
 | | INTERFERON REGULATORY FACTOR-2 DNA BINDING DOMAIN, NMR, 20 STRUCTURES | | 分子名称: | INTERFERON REGULATORY FACTOR-2 | | 著者 | Furui, J, Uegaki, K, Yamazaki, T, Shirakawa, M, Swindells, M.B, Harada, H, Taniguchi, T, Kyogoku, Y. | | 登録日 | 1997-11-25 | | 公開日 | 1998-03-18 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the IRF-2 DNA-binding domain: a novel subgroup of the winged helix-turn-helix family.
Structure, 6, 1998
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1IF1
 | | INTERFERON REGULATORY FACTOR 1 (IRF-1) COMPLEX WITH DNA | | 分子名称: | DNA (26-MER), PROTEIN (INTERFERON REGULATORY FACTOR 1) | | 著者 | Escalante, C.R, Yie, J, Thanos, D, Aggarwal, A. | | 登録日 | 1997-09-12 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of IRF-1 with bound DNA reveals determinants of interferon regulation.
Nature, 391, 1998
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1IRF
 | | INTERFERON REGULATORY FACTOR-2 DNA BINDING DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | INTERFERON REGULATORY FACTOR-2 | | 著者 | Furui, J, Uegaki, K, Yamazaki, T, Shirakawa, M, Swindells, M.B, Harada, H, Taniguchi, T, Kyogoku, Y. | | 登録日 | 1997-11-24 | | 公開日 | 1998-01-28 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the IRF-2 DNA-binding domain: a novel subgroup of the winged helix-turn-helix family.
Structure, 6, 1998
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2PI0
 | | Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer | | 分子名称: | Interferon regulatory factor 3, PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2 | | 著者 | Escalante, C.R, Nistal-Villan, E, Leyi, S, Garcia-Sastre, A, Aggarwal, A.K. | | 登録日 | 2007-04-12 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.
Mol.Cell, 26, 2007
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8JKN
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8JKL
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8JKQ
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8JKO
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8JKS
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1T2K
 | | Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA | | 分子名称: | 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ... | | 著者 | Panne, D, Maniatis, T, Harrison, S.C. | | 登録日 | 2004-04-21 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
Embo J., 23, 2004
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2O61
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