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7AEJ
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Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors
分子名称: 2H10, Envelope glycoprotein gp160,Envelope glycoprotein gp160
著者Caillat, C, Guilligay, D, Weissenhorn, W.
登録日2020-09-17
公開日2021-05-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies.
Elife, 10, 2021
2XRA
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crystal structure of the HK20 Fab in complex with a gp41 mimetic 5- Helix
分子名称: HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN, ...
著者Sabin, C, Corti, D, Buzon, V, Seaman, M.S, Lutje Hulsik, D, Hinz, A, Vanzetta, F, Agatic, G, Silacci, C, Langedijk, J.P.M, Mainetti, L, Scarlatti, G, Sallusto, F, Weiss, R, Lanzavecchia, A, Weissenhorn, W.
登録日2010-09-13
公開日2010-12-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
3WFV
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HIV-1 CRF07 gp41
分子名称: Envelope glycoprotein gp160
著者Du, J, Xue, H, Ma, J, Liu, F, Zhou, J, Shao, Y, Qiao, W, Liu, X.
登録日2013-07-24
公開日2013-10-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of HIV CRF07 B'/C gp41 reveals a hyper-mutant site in the middle of HR2 heptad repeat
Virology, 446, 2013
6R2G
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Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34
分子名称: Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41
著者Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B.
登録日2019-03-17
公開日2019-07-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins.
J.Mol.Biol., 431, 2019
1DLB
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HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES
分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41
著者Shu, W, Liu, J, Ji, H, Rading, L, Jiang, S, Lu, M.
登録日1999-12-09
公開日1999-12-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides.
Biochemistry, 39, 2000
1DF4
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INTERACTIONS BETWEEN HIV-1 GP41 CORE AND DETERGENTS AND THEIR IMPLICATIONS FOR MEMBRANE FUSION
分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41
著者Shu, W, Ji, H, Lu, M.
登録日1999-11-17
公開日1999-11-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion.
J.Biol.Chem., 275, 2000
3CYO
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Structure of a longer thermalstable core domain of HIV-1 GP41 containing the enfuvirtide resistance mutation N43D and complementary mutation E137K
分子名称: Transmembrane protein
著者Wang, Z.M, Dwyer, J.J.
登録日2008-04-25
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
3CP1
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Structure of a longer thermalstable core domain of HIV-1 gp41 containing the enfuvirtide resistance mutation N43D
分子名称: Transmembrane Protein
著者Wang, Z.M, Dwyer, J.J.
登録日2008-03-30
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
2OT5
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Crystal structure of the HIV gp41 core with the enfuvirtide resistance mutation N43D
分子名称: HIV-1 gp41 glycoprotein
著者Bai, X, Seedorff, J.E, Green, J, Dwyer, J.J.
登録日2007-02-07
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
6SNE
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crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ...
著者Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W.
登録日2019-08-23
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
4KHT
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Triple helix bundle of GP41 complexed with fab 8066
分子名称: 8066 heavy chain, 8066 light chain, Gp41 helix
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2013-05-01
公開日2014-03-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
2SIV
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SIV GP41 CORE STRUCTURE
分子名称: SIV GP41 GLYCOPROTEIN
著者Malashkevich, V.N, Chan, D.C, Chutkowski, C.T, Kim, P.S.
登録日1998-06-17
公開日1998-08-19
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides.
Proc.Natl.Acad.Sci.USA, 95, 1998
4KHX
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Crystal structure of gp41 helix complexed with antibody 8062
分子名称: 8062 heavy chain, 8062 light chain, gp41 helix
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2013-05-01
公開日2014-03-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.921 Å)
主引用文献Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
1DF5
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INTERACTIONS BETWEEN HIV-1 GP41 CORE AND DETERGENTS AND THEIR IMPLICATIONS FOR MEMBRANE FUSION
分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41
著者Shu, W, Ji, H, Lu, M.
登録日1999-11-17
公開日1999-11-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion.
J.Biol.Chem., 275, 2000
1ENV
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ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41
分子名称: HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41
著者Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C.
登録日1997-06-27
公開日1997-11-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Atomic structure of the ectodomain from HIV-1 gp41.
Nature, 387, 1997
1F23
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CONTRIBUTION OF A BURIED HYDROGEN BOND TO HIV-1 ENVELOPE GLYCOPROTEIN STRUCTURE AND FUNCTION
分子名称: TRANSMEMBRANE GLYCOPROTEIN
著者Liu, J, Shu, W, Fagan, M, Nunberg, J.H, Lu, M.
登録日2000-05-23
公開日2001-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional analysis of the HIV gp41 core containing an Ile573 to Thr substitution: implications for membrane fusion.
Biochemistry, 40, 2001
1QBZ
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THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MERCURY (II) ION, ...
著者Yang, Z.-N, Mueser, T.C, Kaufman, J, Stahl, S.J, Wingfield, P.T, Hyde, C.C.
登録日1999-04-28
公開日1999-05-17
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
J.Struct.Biol., 126, 1999
1QCE
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SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE PLUS 29 SIMULATED ANNEALING STRUCTURES
分子名称: PROTEIN (GP41)
著者Clore, G.M.
登録日1999-04-30
公開日1999-07-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Measurement of Residual Dipolar Couplings of Macromolecules Aligned in the Nematic Phase of Acolloidal Suspension of Rod-Shaped Viruses
J.Am.Chem.Soc., 121, 1999
1SZT
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ATOMIC STRUCTURE OF A THERMOSTABLE SUBDOMAIN OF HIV-1 GP41
分子名称: HIV-1 ENVELOPE GLYCOPROTEIN GP41
著者Tan, K, Lu, M, Wang, J.-H.
登録日1997-07-28
公開日1997-12-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic structure of a thermostable subdomain of HIV-1 gp41.
Proc.Natl.Acad.Sci.USA, 94, 1997
1K33
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Crystal structure analysis of the gp41 core mutant
分子名称: Transmembrane glycoprotein GP41
著者Shu, W, Lu, M.
登録日2001-10-01
公開日2001-10-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
1K34
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Crystal structure analysis of gp41 core mutant
分子名称: Transmembrane glycoprotein GP41
著者Shu, W, Lu, M.
登録日2001-10-01
公開日2001-10-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
1JQ0
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Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure.
分子名称: gp41 envelope protein
著者Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M.
登録日2001-08-03
公開日2002-04-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex.
J.Biol.Chem., 277, 2002
1JPX
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Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Wild type.
分子名称: gp41 envelope protein
著者Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M.
登録日2001-08-03
公開日2002-04-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex.
J.Biol.Chem., 277, 2002
5KA5
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HIV-1 gp41 variant V549E resistance mutation
分子名称: Transmembrane glycoprotein gp41
著者Bhardwaj, A, Khasnis, M.D, Halkidis, K, Root, M.J.
登録日2016-06-01
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
PLoS Pathog., 12, 2016
5KA6
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HIV-1 gp41 variant Q552R and L555M resistance mutations
分子名称: Transmembrane protein gp41
著者Bhardwaj, A, Khasnis, M.D, Halkidis, K, Root, M.J.
登録日2016-06-01
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
PLoS Pathog., 12, 2016

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