PDB: 15 件ウェブページステータス検索Chemie searchBIRD

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1GOE	Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists. 分子名称: CORTICOTROPIN RELEASING HORMONE 著者 Spyroulias, G.A, Papazacharias, S, Pairas, G, Cordopatis, P. 登録日 2001-10-20 公開日 2001-10-31 最終更新日 2015-10-21 実験手法 SOLUTION NMR 主引用文献 Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone Eur.J.Biochem., 269, 2002
1GO9	Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists. 分子名称: CORTICOTROPIN RELEASING HORMONE 著者 Spyroulias, G.A, Papazacharias, S, Pairas, G, Cordopatis, P. 登録日 2001-10-20 公開日 2001-10-31 最終更新日 2016-12-21 実験手法 SOLUTION NMR 主引用文献 Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone. Implications for Design of Crh Antagonists. Eur.J.Biochem., 269, 2002
2RMG	Human Urocortin 2 分子名称: Urocortin-2 著者 Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. 登録日 2007-10-16 公開日 2008-01-01 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
2RMF	Human Urocortin 1 分子名称: Urocortin 著者 Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. 登録日 2007-10-16 公開日 2008-01-01 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
2RMH	Human Urocortin 3 分子名称: Urocortin-3 著者 Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. 登録日 2007-10-16 公開日 2008-01-01 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
3EHU	Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Corticoliberin, ... 著者 Pioszak, A.A, Xu, H.E. 登録日 2008-09-14 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283, 2008
3EHT	Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF 分子名称: Corticoliberin, FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Pioszak, A.A, Xu, H.E. 登録日 2008-09-14 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283, 2008
3N96	Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 分子名称: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E. 登録日 2010-05-28 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain To be Published
3N93	Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3 分子名称: GLYCEROL, Maltose binding protein-CRFR2 alpha, Urocortin-3, ... 著者 Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E. 登録日 2010-05-28 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain To be Published
3N95	Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2 分子名称: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E. 登録日 2010-05-28 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain To be Published
7TRY	Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein 分子名称: Corticotropin-releasing factor receptor 2, G protein gamma subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhao, L.-H, Lin, J, Mao, C, Zhou, X.E, Ji, S, Shen, D, Xiao, P, Melcher, K, Zhang, Y, Yu, X, Xu, H.E. 登録日 2022-01-31 公開日 2022-11-09 最終更新日 2022-11-16 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor. Nat Commun, 13, 2022
7TS0	Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric Go protein 分子名称: Corticotropin-releasing factor receptor 2,Corticotropin-releasing factor receptor 2,Corticotropin-releasing factor receptor 2,Corticotropin-releasing factor receptor 2,Human corticotropin releasing factor receptor 2, Dominant negative Go alpha subunit, G protein gamma subunit, ... 著者 Zhao, L.-H, Lin, J, Mao, C, Zhou, X.E, Ji, S, Shen, D, Xiao, P, Melcher, K, Zhang, Y, Yu, X, Xu, H.E. 登録日 2022-01-31 公開日 2022-11-09 最終更新日 2022-11-16 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor. Nat Commun, 13, 2022
6PB0	Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 分子名称: CHOLESTEROL, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. 登録日 2019-06-12 公開日 2020-02-12 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
6P9X	CRF1 Receptor Gs GPCR protein complex with CRF1 peptide 分子名称: Corticoliberin, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-06-10 公開日 2020-02-05 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Mol.Cell, 77, 2020
6PB1	Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 分子名称: CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. 登録日 2019-06-12 公開日 2020-02-12 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020