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1S4W
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NMR structure of the cytoplasmic domain of integrin AIIb in DPC micelles
分子名称: Integrin alpha-IIb
著者Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J.
登録日2004-01-19
公開日2004-03-09
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004
7KN0
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BU of 7kn0 by Molmil
Structure of the integrin aIIb(W968V)b3 transmembrane complex
分子名称: Integrin alpha-IIb, Integrin beta-3
著者Situ, A.J, Kim, J, An, W, Kim, C, Ulmer, T.S.
登録日2020-11-03
公開日2021-09-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Insight Into Pathological Integrin alpha IIb beta 3 Activation From Safeguarding The Inactive State.
J.Mol.Biol., 433, 2021
1DPK
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SOLUTION STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE INTEGRIN ALPHA-IIB SUBUNIT
分子名称: INTEGRIN ALPHA-IIB SUBUNIT
著者Vinogradova, O, Haas, T, Plow, E.F, Qin, J.
登録日1999-12-27
公開日2000-02-28
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit.
Proc.Natl.Acad.Sci.USA, 97, 2000
1DPQ
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SOLUTION STRUCTURE OF THE CONSTITUTIVELY ACTIVE MUTANT OF THE INTEGRIN ALPHA IIB CYTOPLASMIC DOMAIN.
分子名称: INTEGRIN ALPHA-IIB SUBUNIT
著者Vinogradova, O, Haas, T, Plow, E.F, Qin, J.
登録日1999-12-27
公開日2000-02-28
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit.
Proc.Natl.Acad.Sci.USA, 97, 2000
2LKJ
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BU of 2lkj by Molmil
Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
分子名称: Integrin alpha-M
著者Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S.
登録日2011-10-12
公開日2011-11-02
最終更新日2011-11-16
実験手法SOLUTION NMR
主引用文献Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011
2LUV
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BU of 2luv by Molmil
Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
分子名称: Integrin alpha-X
著者Chua, G.L, Tang, X, Patra, T.A, Tan, S.M, Bhattacharjya, S.
登録日2012-06-21
公開日2012-07-04
実験手法SOLUTION NMR
主引用文献Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
To be Published
2M3E
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The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2
分子名称: Integrin alpha-L
著者Surya, W, Li, Y, Millet, O, Diercks, T, Torres, J.
登録日2013-01-17
公開日2014-01-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2
To be Published
2N9Y
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BU of 2n9y by Molmil
Structure of the Integrin alphaIIb-beta3(A711P) Transmembrane Complex
分子名称: Integrin alpha-IIb, Integrin beta-3
著者Schmidt, T, Situ, A.J, Ulmer, T.S.
登録日2015-12-14
公開日2016-08-03
実験手法SOLUTION NMR
主引用文献Structural and thermodynamic basis of proline-induced transmembrane complex stabilization.
Sci Rep, 6, 2016
2K1A
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BU of 2k1a by Molmil
Bicelle-embedded integrin alpha(IIB) transmembrane segment
分子名称: Integrin alpha-IIb
著者Lau, T.-L, Dua, V, Ulmer, T.S.
登録日2008-02-25
公開日2008-04-15
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of the Integrin {alpha}IIb Transmembrane Segment.
J.Biol.Chem., 283, 2008
2K8O
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BU of 2k8o by Molmil
Solution structure of integrin Alpha L
分子名称: Integrin alpha-L
著者Bhunia, A, Bhattacharjya, S, Tan, S.
登録日2008-09-17
公開日2008-12-09
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献NMR Solution Conformations and Interactions of Integrin {alpha}L{beta}2 Cytoplasmic Tails
J.Biol.Chem., 284, 2009
2K9J
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BU of 2k9j by Molmil
Integrin alphaIIb-beta3 transmembrane complex
分子名称: Integrin alpha-IIb light chain, Integrin beta-3
著者Lau, T, Kim, C, Ginsberg, M.H, Ulmer, T.S.
登録日2008-10-15
公開日2009-03-24
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
Embo J., 28, 2009
2LKE
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BU of 2lke by Molmil
Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
分子名称: Integrin alpha-M
著者Chua, G.L, Tang, X.Y, Amalraj, M, Bhattacharjya, S, Tan, S.M.
登録日2011-10-11
公開日2011-11-02
最終更新日2011-11-16
実験手法SOLUTION NMR
主引用文献Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011
8T2U
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Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
8T2V
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Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
7LA4
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Integrin AlphaIIbBeta3-PT25-2 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J.
登録日2021-01-05
公開日2022-01-12
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding.
Blood Adv, 5, 2021
7SFT
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BU of 7sft by Molmil
Filamin complex-2
分子名称: Filamin-A, Integrin alpha-IIb light chain, form 2
著者Liu, J, Qin, J.
登録日2021-10-04
公開日2023-04-12
最終更新日2023-10-25
実験手法SOLUTION NMR
主引用文献A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
7SC4
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BU of 7sc4 by Molmil
filamin complex-1
分子名称: Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION
著者Liu, J, Qin, J.
登録日2021-09-27
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
8GCE
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The Extracellular Domain of Integrin AlphaIIbBeta3 in Intermediate State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huo, T, Wu, H, Wang, Z.
登録日2023-03-01
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Full-length AlphaIIbBeta3 CryoEM structure reveals intact integrin initiate-activation intrinsic architecture
To Be Published
8GCD
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Full length Integrin AlphaIIbBeta3 in inactive state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huo, T, Wu, H, Wang, Z.
登録日2023-03-01
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Full-length AlphaIIbBeta3 CryoEM structure reveals intact integrin initiate-activation intrinsic architecture
To Be Published
6UJC
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BU of 6ujc by Molmil
Integrin alpha-v beta-8 in complex with the Fabs C6-RGD3 and 11D12v2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C6-RGD3 heavy chain Fab, ...
著者Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L.
登録日2019-10-02
公開日2020-02-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Cell, 180, 2020
6UJB
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Integrin alpha-v beta-8 in complex with the Fabs C6D4 and 11D12v2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C6D4 heavy chain Fab, ...
著者Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L.
登録日2019-10-02
公開日2020-02-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Cell, 180, 2020
1KUZ
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BU of 1kuz by Molmil
Solution Structure of the Membrane Proximal Regions of alpha-IIb and beta-3 Integrins
分子名称: integrin alpha-IIb, integrin beta-3
著者Weljie, A.M, Hwang, P.M, Vogel, H.J.
登録日2002-01-22
公開日2002-05-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KUP
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BU of 1kup by Molmil
Solution Structure of the Membrane Proximal Regions of alpha-IIb and beta-3 Integrins
分子名称: integrin alpha-IIb, integrin beta-3
著者Weljie, A.M, Hwang, P.M, Vogel, H.J.
登録日2002-01-22
公開日2002-05-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits.
Proc.Natl.Acad.Sci.USA, 99, 2002
1M8O
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Platelet integrin alfaIIb-beta3 cytoplasmic domain
分子名称: platelet integrin alfaIIb subunit: cytoplasmic domain, platelet integrin beta3 subunit: cytoplasmic domain
著者Vinogradova, O, Velyvis, A, Velyviene, A, Hu, B, Haas, T, Plow, E.F, Qin, J.
登録日2002-07-25
公開日2002-09-18
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A Structural mechanism of integrin alfaiib beta3 "Inside-out" Activation as regulated by its cytoplasmic face.
Cell(Cambridge,Mass.), 110, 2002
2MTP
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The structure of Filamin repeat 21 bound to integrin
分子名称: Filamin-A, Integrin alpha-IIb, Integrin beta-3
著者Liu, J, Qin, J.
登録日2014-08-28
公開日2015-04-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural mechanism of integrin inactivation by filamin.
Nat.Struct.Mol.Biol., 22, 2015

 

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