2M7Z
 
 | | Structure of SmTSP2EC2 | | 分子名称: | CD63-like protein Sm-TSP-2 | | 著者 | Mulvenna, J, Jia, X. | | 登録日 | 2013-05-02 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure, membrane interactions, and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni
J.Biol.Chem., 289, 2014
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5TCX
 | | Crystal structure of human tetraspanin CD81 | | 分子名称: | CD81 antigen, CHOLESTEROL | | 著者 | Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C. | | 登録日 | 2016-09-16 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
Cell, 167, 2016
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1IV5
 | | New Crystal Form of Human CD81 Large Extracellular Loop. | | 分子名称: | CD81 antigen | | 著者 | Kitadokoro, K, Bolognesi, M, Grandi, G, Marco, P, Galli, G, Petracca, R, Fabiana, F. | | 登録日 | 2002-03-14 | | 公開日 | 2003-01-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Subunit Association and Conformational Flexibility in the Head-subdomain of Human CD81 Large Extracellular Loop.
Biol.Chem., 383, 2002
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7JIC
 | | Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment | | 分子名称: | B-lymphocyte antigen CD19, CD81 antigen, Coltuximab Heavy Chain, ... | | 著者 | Susa, K.J, Rawson, S, Kruse, A.C, Blacklow, S.C. | | 登録日 | 2020-07-23 | | 公開日 | 2021-01-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81
Science, 371, 2021
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6K4J
 | | Crystal Structure of the the CD9 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CD9 antigen, NICKEL (II) ION, ... | | 著者 | Umeda, R, Nishizawa, T, Sato, K, Nureki, O. | | 登録日 | 2019-05-24 | | 公開日 | 2020-05-13 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Structural insights into tetraspanin CD9 function.
Nat Commun, 11, 2020
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1G8Q
 | | CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS | | 分子名称: | CD81 ANTIGEN, EXTRACELLULAR DOMAIN | | 著者 | Kitadokoro, K, Bolognesi, M, Bordo, D, Grandi, G, Galli, G, Petracca, R, Falugi, F. | | 登録日 | 2000-11-20 | | 公開日 | 2001-02-21 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs.
EMBO J., 20, 2001
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7ZW1
 | | Human PRPH2-ROM1 hetero-dimer | | 分子名称: | Nanobody, Peripherin-2, Rod outer segment membrane protein 1 | | 著者 | El Mazouni, D, Gros, P. | | 登録日 | 2022-05-17 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of peripherin-2 and ROM1 suggest multiple roles in photoreceptor membrane morphogenesis.
Sci Adv, 8, 2022
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6U9S
 | | Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab | | 分子名称: | 5A6 FAB Heavy Chain, 5A6 FAB Light Chain, CD81 antigen, ... | | 著者 | Susa, K.J, Seegar, T.C.M, Blacklow, S.C.B, Kruse, A.C. | | 登録日 | 2019-09-09 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking.
Elife, 9, 2020
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7MWS
 | | Crystal structure of tamarin CD81 large extracellular loop | | 分子名称: | CD81 protein, GLYCEROL, TETRAETHYLENE GLYCOL | | 著者 | Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. | | 登録日 | 2021-05-17 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into hepatitis C virus receptor binding and entry.
Nature, 598, 2021
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6RLR
 | | Crystal structure of CD9 large extracellular loop | | 分子名称: | CD9 antigen | | 著者 | Neviani, V, Kroon-Batenburg, L, Lutz, M, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | | 登録日 | 2019-05-02 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F.
Life Sci Alliance, 3, 2020
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6Z1V
 | | Structure of the EC2 domain of CD9 in complex with nanobody 4E8 | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CD9 antigen, ... | | 著者 | Oosterheert, W, Pearce, N.M, Gros, P. | | 登録日 | 2020-05-14 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-09-30 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F.
Life Sci Alliance, 3, 2020
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6Z20
 | | Structure of the EC2 domain of CD9 in complex with nanobody 4C8 | | 分子名称: | CD9 antigen, CHLORIDE ION, GLYCEROL, ... | | 著者 | Oosterheert, W, Manshande, J, Pearce, N.M, Lutz, M, Gros, P. | | 登録日 | 2020-05-14 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F.
Life Sci Alliance, 3, 2020
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6RLO
 | | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | | 分子名称: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | | 登録日 | 2019-05-02 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody
To Be Published
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5DFV
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5DFW
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7RD5
 | | Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab | | 分子名称: | 1C12 Fab Heavy Chain, 1C12 Fab Light Chain, Tetraspanin-15 | | 著者 | Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C. | | 登録日 | 2021-07-09 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.
Structure, 30, 2022
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7RDB
 | | Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) | | 分子名称: | Tetraspanin-15 | | 著者 | Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C. | | 登録日 | 2021-07-09 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.
Structure, 30, 2022
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6EJG
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6EJM
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6EK2
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3X0F
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3X0E
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3X0G
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5M3D
 | | Structural tuning of CD81LEL (space group P31) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, PHOSPHATE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-14 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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5M4R
 | | Structural tuning of CD81LEL (space group C2) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, SULFATE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-19 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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