1ALK
 
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1ALH
 | | KINETICS AND CRYSTAL STRUCTURE OF A MUTANT E. COLI ALKALINE PHOSPHATASE (ASP-369-->ASN): A MECHANISM INVOLVING ONE ZINC PER ACTIVE SITE | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, SULFATE ION, ... | | 著者 | Tibbitts, T.T, Xu, X, Kantrowitz, E.R. | | 登録日 | 1994-08-23 | | 公開日 | 1995-02-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Kinetics and crystal structure of a mutant Escherichia coli alkaline phosphatase (Asp-369-->Asn): a mechanism involving one zinc per active site.
Protein Sci., 3, 1994
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1ALI
 | | ALKALINE PHOSPHATASE MUTANT (H412N) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Ma, L, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-06-02 | | 公開日 | 1995-11-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
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1ALJ
 | | ALKALINE PHOSPHATASE MUTANT (H412N) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Ma, L, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-06-02 | | 公開日 | 1995-11-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
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1AJC
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1AJD
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1AJA
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1AJB
 | | THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Dealwis, C.G, Chen, L, Abad-Zapatero, C. | | 登録日 | 1995-08-19 | | 公開日 | 1995-11-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | 3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
Protein Eng., 8, 1995
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1ANJ
 | | ALKALINE PHOSPHATASE (K328H) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-09-06 | | 公開日 | 1996-01-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
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1ANI
 | | ALKALINE PHOSPHATASE (D153H, K328H) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-09-06 | | 公開日 | 1996-01-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
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2ANH
 | | ALKALINE PHOSPHATASE (D153H) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-09-06 | | 公開日 | 1996-01-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
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1HQA
 | | ALKALINE PHOSPHATASE (H412Q) | | 分子名称: | ALKALINE PHOSPHATASE, ZINC ION | | 著者 | Ma, L, Kantrowitz, E.R. | | 登録日 | 1995-11-30 | | 公開日 | 1996-03-08 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites.
Biochemistry, 35, 1996
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1URA
 | | ALKALINE PHOSPHATASE (D51ZN) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R. | | 登録日 | 1996-02-03 | | 公開日 | 1996-07-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 257, 1996
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1URB
 | | ALKALINE PHOSPHATASE (N51MG) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R. | | 登録日 | 1996-02-03 | | 公開日 | 1996-07-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 257, 1996
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1HJK
 | | ALKALINE PHOSPHATASE MUTANT H331Q | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Murphy, J.E, Stec, B, Ma, L, Kantrowitz, E.R. | | 登録日 | 1997-05-30 | | 公開日 | 1997-10-15 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Trapping and visualization of a covalent enzyme-phosphate intermediate.
Nat.Struct.Biol., 4, 1997
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1ELZ
 | | E. COLI ALKALINE PHOSPHATASE MUTANT (S102G) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R. | | 登録日 | 1998-02-10 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
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1ELY
 | | E. COLI ALKALINE PHOSPHATASE MUTANT (S102C) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R. | | 登録日 | 1998-02-10 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
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1ELX
 | | E. COLI ALKALINE PHOSPHATASE MUTANT (S102A) | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R. | | 登録日 | 1998-02-10 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
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1B8J
 | | ALKALINE PHOSPHATASE COMPLEXED WITH VANADATE | | 分子名称: | MAGNESIUM ION, PROTEIN (ALKALINE PHOSPHATASE), SULFATE ION, ... | | 著者 | Holtz, K.M, Stec, B, Kantrowitz, E.R. | | 登録日 | 1999-02-01 | | 公開日 | 1999-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A model of the transition state in the alkaline phosphatase reaction.
J.Biol.Chem., 274, 1999
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1ED8
 | | STRUCTURE OF E. COLI ALKALINE PHOSPHATASE INHIBITED BY THE INORGANIC PHOSPHATE AT 1.75A RESOLUTION | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stec, B, Holtz, K.M, Kantrowitz, E.R. | | 登録日 | 2000-01-27 | | 公開日 | 2000-09-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A revised mechanism for the alkaline phosphatase reaction involving three metal ions.
J.Mol.Biol., 299, 2000
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1ED9
 | | STRUCTURE OF E. COLI ALKALINE PHOSPHATASE WITHOUT THE INORGANIC PHOSPHATE AT 1.75A RESOLUTION | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Stec, B, Holtz, K.M, Kantrowitz, E.R. | | 登録日 | 2000-01-27 | | 公開日 | 2000-09-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A revised mechanism for the alkaline phosphatase reaction involving three metal ions.
J.Mol.Biol., 299, 2000
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1EW2
 | | CRYSTAL STRUCTURE OF A HUMAN PHOSPHATASE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHATASE, ... | | 著者 | Le Du, M.H, Stigbrand, T, Taussig, M.J, Menez, A, Stura, E.A. | | 登録日 | 2000-04-21 | | 公開日 | 2001-04-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.
J.Biol.Chem., 276, 2001
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1EW9
 | | ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH MERCAPTOMETHYL PHOSPHONATE | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, MERCAPTOMETHYL PHOSPHONATE, ... | | 著者 | Holtz, K.M, Stec, B, Meyers, J.K, Antonelli, S.M, Widlanski, T.S, Kantrowitz, E.R. | | 登録日 | 2000-04-24 | | 公開日 | 2002-05-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
Protein Sci., 9, 2000
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1EW8
 | | ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH PHOSPHONOACETIC ACID | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Holtz, K.M, Stec, B, Myers, J.K, Antonelli, S.M, Widlanski, T.S, Kantrowitz, E.R. | | 登録日 | 2000-04-24 | | 公開日 | 2002-05-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
Protein Sci., 9, 2000
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1K7H
 | | CRYSTAL STRUCTURE OF SHRIMP ALKALINE PHOSPHATASE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALKALINE PHOSPHATASE, MALEIC ACID, ... | | 著者 | De Backer, M.E, Mc Sweeney, S, Rasmussen, H.B, Riise, B.W, Lindley, P, Hough, E. | | 登録日 | 2001-10-19 | | 公開日 | 2002-07-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
J.Mol.Biol., 318, 2002
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