Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4LNV
DownloadVisualize
BU of 4lnv by Molmil
Crystal Structure of TEP1s
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thioester-containing protein I
著者Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
登録日2013-07-12
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Plos Pathog., 8, 2012
6TAV
DownloadVisualize
BU of 6tav by Molmil
Crystal structure of endopeptidase-induced alpha2-macroglobulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
著者Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J.
登録日2019-10-30
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin
Proc.Natl.Acad.Sci.USA, 2022
3T4A
DownloadVisualize
BU of 3t4a by Molmil
Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution
分子名称: Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ...
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
6EHG
DownloadVisualize
BU of 6ehg by Molmil
complement component C3b in complex with a nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R.
登録日2017-09-13
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J. Biol. Chem., 293, 2018
7ZGJ
DownloadVisualize
BU of 7zgj by Molmil
Trypanosoma brucei gambiense ISG65 in complex with human complement component C3
分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3, ...
著者Suelzen, H, Zoll, S.
登録日2022-04-03
公開日2023-04-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun, 14, 2023
7ZGK
DownloadVisualize
BU of 7zgk by Molmil
Trypanosoma brucei gambiense ISG65 in complex with human complement component C3b
分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3 beta chain, ...
著者Suelzen, H, Zoll, S.
登録日2022-04-03
公開日2023-04-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun, 14, 2023
2A74
DownloadVisualize
BU of 2a74 by Molmil
Human Complement Component C3c
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Complement Component C3c, GLYCEROL, ...
著者Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P.
登録日2005-07-04
公開日2005-09-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2A73
DownloadVisualize
BU of 2a73 by Molmil
Human Complement Component C3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P.
登録日2005-07-04
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
7VOO
DownloadVisualize
BU of 7voo by Molmil
Induced alpha-2-macroglobulin monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
著者Huang, X, Wang, Y, Ping, Z.
登録日2021-10-14
公開日2022-10-19
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
7VON
DownloadVisualize
BU of 7von by Molmil
Native alpha-2-macroglobulin monomer
分子名称: Alpha-2-macroglobulin
著者Huang, X, Wang, Y.
登録日2021-10-14
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
6YO6
DownloadVisualize
BU of 6yo6 by Molmil
Structure of iC3b1
分子名称: hC3Nb1, iC3b1 alpha chain, iC3b1 beta chain
著者Jensen, R.K, Andersen, G.R.
登録日2020-04-14
公開日2021-02-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.
J Immunol., 206, 2021
8OQ3
DownloadVisualize
BU of 8oq3 by Molmil
Structure of methylamine treated human complement C3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gadeberg, T.A.F, Andersen, G.R.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of methylamine treated human complement C3
To Be Published
8OVB
DownloadVisualize
BU of 8ovb by Molmil
Human Complement C3b in complex with Trypanosoma brucei ISG65.
分子名称: Complement C3, Complement C3f fragment, ISG65 G
著者Cook, A.D, Higgins, M.K.
登録日2023-04-25
公開日2024-02-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular mechanism of complement factor C3b inhibition by the trypanosome ISG65 receptor.
To be published
3CU7
DownloadVisualize
BU of 3cu7 by Molmil
Human Complement Component 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Fredslund, F, Andersen, G.R.
登録日2008-04-16
公開日2008-06-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
6YSQ
DownloadVisualize
BU of 6ysq by Molmil
The hC4Nb8 complement inhibitory nanobody in complex with C4b
分子名称: Complement C4 beta chain, Complement C4 gamma chain, Complement C4-A alpha chain, ...
著者Zarantonello, A, Laursen, N.S, Andersen, G.R.
登録日2020-04-23
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
J Immunol., 205, 2020
2PN5
DownloadVisualize
BU of 2pn5 by Molmil
Crystal Structure of TEP1r
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
著者Baxter, R.H.G.
登録日2007-04-23
公開日2007-07-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QKI
DownloadVisualize
BU of 2qki by Molmil
Human C3c in complex with the inhibitor compstatin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ...
著者Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P.
登録日2007-07-11
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
3FRP
DownloadVisualize
BU of 3frp by Molmil
Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb
分子名称: CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ...
著者Krishnan, V, Narayana, S.V.L.
登録日2009-01-08
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb.
Structure, 17, 2009
4ZIQ
DownloadVisualize
BU of 4ziq by Molmil
Crystal structure of trypsin activated alpha-2-macroglobulin from Escherichia coli.
分子名称: CHLORIDE ION, GLYCEROL, Uncharacterized lipoprotein YfhM
著者Garcia-Ferrer, I, Arede, P, Gomez-Blanco, J, Luque, D, Duquerroy, S, Caston, J.R, Goulas, T, Gomis-Ruth, X.F.
登録日2015-04-28
公開日2015-06-10
最終更新日2015-07-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZIU
DownloadVisualize
BU of 4ziu by Molmil
Crystal structure of native alpha-2-macroglobulin from Escherichia coli spanning the residues from domain MG7 to the C-terminus.
分子名称: GLYCEROL, NICKEL (II) ION, Uncharacterized lipoprotein YfhM
著者Garcia-Ferrer, I, Arede, P, Gomez-Blanco, J, Luque, D, Duquerroy, S, Caston, J.R, Goulas, T, Gomis-Ruth, X.F.
登録日2015-04-28
公開日2015-06-10
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
2I07
DownloadVisualize
BU of 2i07 by Molmil
Human Complement Component C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P.
登録日2006-08-10
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
5A42
DownloadVisualize
BU of 5a42 by Molmil
Cryo-EM single particle 3D reconstruction of the native conformation of E. coli alpha-2-macroglobulin (ECAM)
分子名称: UNCHARACTERIZED LIPOPROTEIN YFHM
著者Garcia-Ferrer, I, Arede, P, Gomez-Blanco, J, Luque, D, Duquerroy, S, Caston, J.R, Goulas, T, Gomis-Ruth, F.X.
登録日2015-06-04
公開日2015-07-29
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献Structural and Functional Insights Into Escherichia Coli Alpha2- Macroglobulin Endopeptidase Snap-Trap Inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4D94
DownloadVisualize
BU of 4d94 by Molmil
Crystal Structure of TEP1r
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
登録日2012-01-11
公開日2012-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Plos Pathog., 8, 2012
2ICE
DownloadVisualize
BU of 2ice by Molmil
CRIg bound to C3c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
著者Wiesmann, C.
登録日2006-09-12
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2ICF
DownloadVisualize
BU of 2icf by Molmil
CRIg bound to C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
著者Wiesmann, C.
登録日2006-09-12
公開日2006-11-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006

217705

件を2024-03-27に公開中

PDB statisticsPDBj update infoContact PDBjnumon