PDB: 150 件ウェブページステータス検索Chemie searchBIRD

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4YOL	Human fibroblast growth factor-1 C16S/A66C/C117A/P134A 分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE 著者 Xia, X, Blaber, M. 登録日 2015-03-11 公開日 2016-03-16 最終更新日 2019-02-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. J.Pharm.Sci., 105, 2016
4XKI	Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R 分子名称: Fibroblast growth factor 1, GLYCEROL, NONAETHYLENE GLYCOL, ... 著者 Xia, X. 登録日 2015-01-12 公開日 2016-01-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biophysical characterizations of Fibroblast Growth Factor - 1 mutant with increased heparin binding affinity To Be Published
8OM6	Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2 分子名称: Fibroblast growth factor 2 著者 Marek, M, Chaloupkova, R, de La Bourdonnaye, G. 登録日 2023-03-31 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2 To Be Published
1BLD	BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR 分子名称: BASIC FIBROBLAST GROWTH FACTOR 著者 Powers, R, Seddon, A.P, Bohlen, P, Moy, F.J. 登録日 1996-05-20 公開日 1996-11-08 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy. Biochemistry, 35, 1996
4CJM	Crystal structure of human FGF18 分子名称: FIBROBLAST GROWTH FACTOR 18, SULFATE ION 著者 Brown, A, Adam, L.E, Blundell, T.L. 登録日 2013-12-21 公開日 2014-04-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Crystal Structure of Fibroblast Growth Factor 18 (Fgf18) Protein Cell, 5, 2014
5X1O	PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Fibroblast growth factor 2 著者 Tsao, Y.H. 登録日 2017-01-26 公開日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study To Be Published
1YTO	Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2005-02-10 公開日 2006-01-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2006
1Z2V	Crystal Structure of Glu60 deletion Mutant of Human Acidic Fibroblast Growth Factor 分子名称: Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2005-03-09 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2006
1Z4S	Crystal Structure of Gly19 and Glu60 deletion mutant of Human Acidic Fibroblast Growth Factor 分子名称: Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2005-03-16 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2005
3BAG	Crystal structure of K112N/N114A mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1 著者 Lee, J, Blaber, M. 登録日 2007-11-07 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
4FGF	REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION 著者 Eriksson, A.E, Matthews, B.W. 登録日 1993-02-26 公開日 1993-07-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993
3BAQ	Crystal structure of L26A mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2007-11-08 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BAU	Crystal structure of K12V/L26D/D28A mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2007-11-08 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3O3Q	Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor 分子名称: GLYCEROL, Heparin-binding growth factor 1 著者 Lee, J, Blaber, M. 登録日 2010-07-25 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A polypeptide "building block"top-down symmetric deconstruction". J.Mol.Biol., 407, 2011
3UD8	Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex 分子名称: 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
3UDA	Crystal Structure Analysis of FGF1-Disaccharide(NI24) complex 分子名称: 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
3UD9	Crystal Structure Analysis of FGF1-Disaccharide(NI23) complex 分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
3UD7	Crystal Structure Analysis of FGF1-Disaccharide(NI21) complexes 分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
6KTR	Crystal structure of fibroblast growth factor 19 in complex with Fab 分子名称: Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ... 著者 Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J. 登録日 2019-08-28 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.59775758 Å) 主引用文献 Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111, 2020
6M6F	Solution structure of disulfide bond mutaion of the core domain of Fibroblast growth factor 21 (FGF21) 分子名称: Fibroblast growth factor 21 著者 Zhu, L, Zhao, H, Wang, J. 登録日 2020-03-14 公開日 2021-01-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamic folding modulation generates FGF21 variant against diabetes. Embo Rep., 22, 2021
6M6E	Solution structure of the core domain of Fibroblast growth factor 21 (FGF21) 分子名称: Fibroblast growth factor 21 著者 Zhu, L, Zhao, H, Wang, J. 登録日 2020-03-14 公開日 2021-01-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamic folding modulation generates FGF21 variant against diabetes. Embo Rep., 22, 2021
3HBW	Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A) 分子名称: Fibroblast growth factor 13 著者 Mohammadi, M. 登録日 2009-05-05 公開日 2009-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels. J.Biol.Chem., 284, 2009
3HAL	Crystal structure of Rabbit acidic fibroblast growth factor 分子名称: CHLORIDE ION, Fibroblast growth factor 1 isoform 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2009-05-01 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray structure and biophysical properties of rabbit fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65, 2009
3HOM	Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor 分子名称: Acidic fibroblast growth factor, FORMIC ACID, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2009-06-02 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine. J.Mol.Biol., 393, 2009
3K1X	Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate 分子名称: 2,5-dihydroxybenzenesulfonic acid, Heparin-binding growth factor 1 著者 Romero, A, Fernandez, I.S, Gimenez-Gallego, G. 登録日 2009-09-29 公開日 2010-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J.Biol.Chem., 285, 2010

 

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