PDB: 291 件ウェブページステータス検索Chemie searchBIRD

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4QCL	Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA TEMPLATE, ... 著者 Baranovskiy, A.G, Suwa, Y, Babayeva, N.D, Gu, J, Tahirov, T.H. 登録日 2014-05-12 公開日 2014-11-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Activity and fidelity of human DNA polymerase alpha depend on primer structure J.Biol.Chem., 2018
7Z13	S. cerevisiae CMGE dimer nucleating origin DNA melting 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... 著者 Lewis, J.S, Sousa, J.S, Costa, A. 登録日 2022-02-24 公開日 2022-06-15 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
6AS7	CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2017-08-23 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Activity and fidelity of human DNA polymerase alpha depend on primer structure. J. Biol. Chem., 293, 2018
5EXR	Crystal structure of human primosome 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2015-11-24 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
1CLQ	CRYSTAL STRUCTURE OF A REPLICATION FORK DNA POLYMERASE EDITING COMPLEX AT 2.7 A RESOLUTION 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*AP*GP*TP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*AP*CP*TP*AP*CP*T)-3'), ... 著者 Shamoo, Y, Steitz, T.A. 登録日 1999-04-30 公開日 1999-10-28 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell(Cambridge,Mass.), 99, 1999
1D5A	CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM 分子名称: MAGNESIUM ION, PROTEIN (DNA POLYMERASE), SULFATE ION 著者 Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J. 登録日 1999-10-06 公開日 2000-03-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an archaebacterial DNA polymerase. Structure Fold.Des., 7, 1999
5H12	Crystal structure of Deep Vent DNA Polymerase 分子名称: Deep Vent DNA Polymerase 著者 Hikida, Y, Kimoto, M, Hirao, I, Yokoyama, S. 登録日 2016-10-07 公開日 2017-01-25 最終更新日 2017-08-30 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Crystal structure of Deep Vent DNA polymerase. Biochem. Biophys. Res. Commun., 483, 2017
1IH7	High-Resolution Structure of Apo RB69 DNA Polymerase 分子名称: DNA POLYMERASE, GUANOSINE, POTASSIUM ION 著者 Franklin, M.C, Wang, J, Steitz, T.A. 登録日 2001-04-18 公開日 2001-06-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
2GV9	Crystal structure of the Herpes Simplex virus type 1 DNA polymerase 分子名称: DNA polymerase, GUANIDINE, MERCURY (II) ION, ... 著者 Liu, S. 登録日 2006-05-02 公開日 2006-05-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Crystal structure of the herpes simplex virus 1 DNA polymerase. J.Biol.Chem., 281, 2006
6P1H	Cryo-EM Structure of DNA Polymerase Delta Holoenzyme 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... 著者 Jain, R, Rice, W, Aggarwal, A.K. 登録日 2019-05-19 公開日 2019-10-02 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure and dynamics of eukaryotic DNA polymerase delta holoenzyme. Nat.Struct.Mol.Biol., 26, 2019
1IG9	Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase 分子名称: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... 著者 Franklin, M.C, Wang, J, Steitz, T.A. 登録日 2001-04-17 公開日 2001-06-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
5IUD	Human DNA polymerase alpha in binary complex with a DNA:DNA template-primer 分子名称: DNA polymerase alpha catalytic subunit, DNA primer, DNA template 著者 Coloma, J, Aggarwal, A.K. 登録日 2016-03-17 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Human DNA polymerase alpha in binary complex with a DNA:DNA template-primer. Sci Rep, 6, 2016
6QIB	The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... 著者 Parkash, V, Johansson, E. 登録日 2019-01-18 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε. Nucleic Acids Res., 47, 2019
2JGU	crystal structure of DNA-directed DNA polymerase 分子名称: DNA POLYMERASE, MANGANESE (II) ION 著者 Kim, D.U, Cho, H.S. 登録日 2007-02-15 公開日 2008-04-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Pfu, the High Fidelity DNA Polymerase from Pyrococcus Furiosus. Int.J.Biol.Macromol., 42, 2008
5OMF	Closed, ternary structure of KOD DNA polymerase 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), ... 著者 Kropp, H.M, Betz, K, Wirth, J, Diederichs, K, Marx, A. 登録日 2017-07-31 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
5OMQ	Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
5OMV	Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
2VWK	Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase variant 分子名称: DNA POLYMERASE, SODIUM ION, SULFATE ION 著者 Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. 登録日 2008-06-26 公開日 2008-07-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
2VWJ	Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. 分子名称: 5'-D(*AP*AP*UP*GP*GP*AP*GP*AP*CP*GP *GP*CP*TP*TP*TP*TP*GP*CP*CP*GP*TP*GP*TP*C)-3', DNA POLYMERASE, POTASSIUM ION 著者 Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. 登録日 2008-06-25 公開日 2008-07-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
2ATQ	RB69 single-stranded DNA binding protein-DNA polymerase fusion 分子名称: DNA polymerase, GUANOSINE-5'-DIPHOSPHATE, ZINC ION, ... 著者 Sun, S, Geng, L, Shamoo, Y. 登録日 2005-08-25 公開日 2006-05-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Proteins, 65, 2006
2XHB	Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA 分子名称: 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ... 著者 Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A. 登録日 2010-06-14 公開日 2010-07-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues. Biochemistry, 49, 2010
6FWK	The crystal structure of Pol2CORE-M644G in complex with DNA and an incoming nucleotide 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*(DOC))-3'), ... 著者 Parkash, V, Johansson, E. 登録日 2018-03-06 公開日 2019-01-30 最終更新日 2019-02-06 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon. Nat Commun, 10, 2019
6G0A	The crystal structure of the Pol2 catalytic domain of DNA polymerase epsilon carrying a P301R substitution. 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*DC)-3'), ... 著者 Parkash, V, Johansson, E. 登録日 2018-03-16 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon. Nat Commun, 10, 2019
6H1V	The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*AP*AP*TP*TP*GP*AP*AP*CP*GP*CP*GP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*(DOC))-3'), ... 著者 Parkash, V, Johansson, E. 登録日 2018-07-12 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε. Nucleic Acids Res., 47, 2019
2DTU	Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog 分子名称: 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase 著者 Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. 登録日 2006-07-15 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007

 

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