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5DM3
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Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, L-glutamine synthetase
著者Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2015-09-07
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP
To be published
2J9I
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Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens.
分子名称: GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1
著者Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G.
登録日2006-11-09
公開日2006-12-13
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens.
Structure, 14, 2006
8WWV
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1-naphthylamine GS in complex with ADP and MetSox-P
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
著者Zhang, S.T, Zhou, N.Y.
登録日2023-10-26
公開日2024-01-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation
To Be Published
8WWU
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1-naphthylamine GS in complex with AMP PNP
分子名称: Glutamine synthetase, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Zhang, S.T, Zhou, N.Y.
登録日2023-10-26
公開日2024-01-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation
To Be Published
7CQQ
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GmaS in complex with AMPPNP and MetSox
分子名称: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQL
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Apo GmaS without ligand
分子名称: Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQN
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GmaS in complex with AMPPCP
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQU
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GmaS/ADP/MetSox-P complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MAGNESIUM ION, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQX
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GmaS/ADP complex-Conformation 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQW
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GmaS/ADP complex-Conformation 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CPR
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glutamine synthetase from Drosophila
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase 2 cytoplasmic
著者Yin, H.S, Chen, W.T.
登録日2020-08-07
公開日2021-08-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural Insight into the Contributions of the N-Terminus and Key Active-Site Residues to the Catalytic Efficiency of Glutamine Synthetase 2.
Biomolecules, 10, 2020
7V4H
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Cryo-EM Structure of Glycine max glutamine synthetase GmGS Beta2
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7EVT
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Crystal structure of the N-terminal degron-truncated human glutamine synthetase
分子名称: Glutamine synthetase
著者Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T.
登録日2021-05-22
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of N-terminal degron-truncated human glutamine synthetase.
Acta Crystallogr.,Sect.F, 77, 2021
4XYC
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NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES
分子名称: 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1
著者Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E.
登録日2015-02-02
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies.
Bioorg.Med.Chem.Lett., 25, 2015
8FBP
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BU of 8fbp by Molmil
Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
分子名称: Glutamine synthetase
著者Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-29
公開日2024-02-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
To Be Published
5LDF
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Maltose binding protein genetically fused to dodecameric glutamine synthetase
分子名称: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Coscia, F, Petosa, C, Schoehn, G.
登録日2016-06-25
公開日2016-08-10
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
6PEW
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CryoEM Plasmodium falciparum glutamine synthetase
分子名称: Glutamine synthetase
著者Ho, C.M, Lai, M, Zhou, Z.H.
登録日2019-06-21
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu.
Nat.Methods, 17, 2020
3FKY
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BU of 3fky by Molmil
Crystal structure of the glutamine synthetase Gln1deltaN18 from the yeast Saccharomyces cerevisiae
分子名称: CITRATE ANION, Glutamine synthetase
著者He, Y.X, Gui, L, Liu, Y.Z, Du, Y, Zhou, Y.Y, Li, P, Zhou, C.Z.
登録日2008-12-18
公開日2009-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly
Proteins, 76, 2009
5ZLP
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Crystal structure of glutamine synthetase from helicobacter pylori
分子名称: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Joo, H.K, Lee, J.Y.
登録日2018-03-29
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
4S0R
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BU of 4s0r by Molmil
Structure of GS-TnrA complex
分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
著者Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K.
登録日2015-01-04
公開日2015-03-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
3NG0
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BU of 3ng0 by Molmil
Crystal Structure of Glutamine Synthetase from Synechocystis sp. PCC 6803
分子名称: Glutamine synthetase, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Saelices, L, Cascio, D, Florencio, F.J, Muro-Pastor, M.I.
登録日2010-06-10
公開日2011-06-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Glutamine Synthetase from Synechocystis sp. PCC 6803
To be Published
4S17
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The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
分子名称: ACETATE ION, Glutamine synthetase, MAGNESIUM ION
著者Cuff, M, Tan, K, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-01-08
公開日2015-01-28
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
To be Published
2OJW
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Crystal structure of human glutamine synthetase in complex with ADP and phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-01-15
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
5ZLI
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Crystal structure of glutamine synthetase from helicobacter pylori
分子名称: Glutamine synthetase
著者Joo, H.K, Lee, J.Y.
登録日2018-03-28
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
8DNU
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Human Brain Glutamine Synthetase
分子名称: Glutamine synthetase, MANGANESE (II) ION
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023

 

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