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1ARF	STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING 分子名称: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION 著者 Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E. 登録日 1993-10-01 公開日 1994-01-31 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Structures of DNA-binding mutant zinc finger domains: implications for DNA binding. Protein Sci., 2, 1993
3ZNF	HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FINGER FROM A HUMAN ENHANCER BINDING PROTEIN IN SOLUTION 分子名称: ZINC FINGER, ZINC ION 著者 Gronenborn, A.M, Clore, G.M, Omichinski, J.G. 登録日 1990-07-09 公開日 1992-01-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Biochemistry, 29, 1990
1BBO	HIGH-RESOLUTION SOLUTION STRUCTURE OF THE DOUBLE CYS2*HIS2 ZINC FINGER FROM THE HUMAN ENHANCER BINDING PROTEIN MBP-1 分子名称: HUMAN ENHANCER-BINDING PROTEIN MBP-1, ZINC ION 著者 Clore, G.M, Omichinski, J.G, Gronenborn, A.M. 登録日 1992-05-01 公開日 1993-10-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1. Biochemistry, 31, 1992
4M9E	Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA 分子名称: ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... 著者 Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. 登録日 2013-08-14 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42, 2014
4M9V	Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X. 登録日 2013-08-15 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.969 Å) 主引用文献 DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom. Biochemistry, 52, 2013
7TXC	HIC2 zinc finger domain in complex with the DNA binding motif-2 of the BCL11A enhancer 分子名称: DNA (5'-D(*AP*CP*TP*GP*TP*TP*GP*GP*CP*AP*TP*TP*AP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*TP*AP*AP*TP*GP*CP*CP*AP*AP*CP*AP*GP*T)-3'), Hypermethylated in cancer 2 protein, ... 著者 Horton, J.R, Ren, R, Cheng, X. 登録日 2022-02-08 公開日 2022-06-01 最終更新日 2022-09-28 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nat.Genet., 54, 2022
8H9H	Crystal structure of ZBTB7A in complex with GACCC-containing sequence 分子名称: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ... 著者 Yang, Y. 登録日 2022-10-25 公開日 2023-04-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4. Febs J., 290, 2023
3UK3	Crystal structure of ZNF217 bound to DNA 分子名称: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... 著者 Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. 登録日 2011-11-08 公開日 2012-12-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Rediscovering DNA recognition by classical Zinc Fingers. To be Published
7EYI	Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation 分子名称: BORIC ACID, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... 著者 Yang, Y, Shi, Y.Y. 登録日 2021-05-31 公開日 2021-09-01 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
6PV1	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: Aib in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
4F2J	Crystal structure of ZNF217 bound to DNA, P6522 crystal form 分子名称: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', ZINC ION, Zinc finger protein 217 著者 Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. 登録日 2012-05-08 公開日 2013-02-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217 J.Biol.Chem., 288, 2013
4X9J	EGR-1 with Doubly Methylated DNA 分子名称: DNA (5'-D(*AP*GP*(5CM)P*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*(5CM)P*GP*C)-3'), Early growth response protein 1, ... 著者 White, M.A, Zandarashvili, L, Iwahara, J. 登録日 2014-12-11 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.412 Å) 主引用文献 Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1. Febs Lett., 589, 2015
1JK1	Zif268 D20A Mutant Bound to WT DNA Site 分子名称: 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*G)-3', 5'-D(*TP*CP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... 著者 Miller, J.C, Pabo, C.O. 登録日 2001-07-11 公開日 2001-10-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. J.Mol.Biol., 313, 2001
4GZN	Mouse ZFP57 zinc fingers in complex with methylated DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Liu, Y, Zhang, X, Cheng, X. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev., 26, 2012
6PV2	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: Orn in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
1F2I	COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA 分子名称: 5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3', FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, ZINC ION 著者 Wang, B.S, Grant, R.A, Pabo, C.O. 登録日 2000-05-25 公開日 2001-09-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nat.Struct.Biol., 8, 2001
6PV3	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: altered helix, loop, turn, and sheet 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
6PV0	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: D-Pro in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
1JK2	Zif268 D20A mutant bound to the GCT DNA site 分子名称: 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... 著者 Miller, J.C, Pabo, C.O. 登録日 2001-07-11 公開日 2001-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. J.Mol.Biol., 313, 2001
4ZNF	HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FINGER FROM A HUMAN ENHANCER BINDING PROTEIN IN SOLUTION 分子名称: ZINC FINGER, ZINC ION 著者 Gronenborn, A.M, Clore, G.M, Omichinski, J.G. 登録日 1990-07-09 公開日 1992-01-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Biochemistry, 29, 1990
5A7U	Single-particle cryo-EM of co-translational folded adr1 domain inside the E. coli ribosome exit tunnel. 分子名称: REGULATORY PROTEIN ADR1, ZINC ION 著者 Nilsson, O.B, Hedman, R, Marino, J, Wickles, S, Bischoff, L, Johansson, M, Muller-Lucks, A, Trovato, F, Puglisi, J.D, O'Brien, E, Beckmann, R, von Heijne, G. 登録日 2015-07-10 公開日 2015-09-16 最終更新日 2017-08-23 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Cotranslational Protein Folding Inside the Ribosome Exit Tunnel. Cell Rep., 12, 2015
5EH2	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III 分子名称: DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-27 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
5EI9	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence I 分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*GP*A)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-29 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.921 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
5EGB	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence II 分子名称: DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-26 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.977 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
1G2F	STRUCTURE OF A CYS2HIS2 ZINC FINGER/TATA BOX COMPLEX (TATAZF;CLONE #6) 分子名称: 5'-D(*GP*AP*CP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*AP*G)-3', 5'-D(*TP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*GP*TP*CP*C)-3', TATA BOX ZINC FINGER PROTEIN, ... 著者 Wolfe, S.A, Grant, R.A, Elrod-Erickson, M, Pabo, C.O. 登録日 2000-10-18 公開日 2001-09-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes. Structure, 9, 2001

 

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