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8Y7E
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Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
分子名称: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-04
公開日2024-03-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-02
公開日2024-03-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8UI0
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BU of 8ui0 by Molmil
Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated
分子名称: DNA, DNA (38-MER), DNA-directed RNA polymerase II subunit E, ...
著者Vos, S.M, Su, B.G.
登録日2023-10-09
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
8UHG
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BU of 8uhg by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Vos, S.M, Su, B.G.
登録日2023-10-09
公開日2024-03-20
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
8UHD
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BU of 8uhd by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Su, B.G, Vos, S.M.
登録日2023-10-08
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
8UHA
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BU of 8uha by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - tilted
分子名称: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ...
著者Vos, S.M, Su, B.G.
登録日2023-10-08
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
8SGH
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BU of 8sgh by Molmil
Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS
分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1
著者Gonzalez, A, Fung, H.Y.J, Chook, Y.M.
登録日2023-04-12
公開日2023-06-14
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Structure, 31, 2023
8RZV
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Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
著者Dunnett, L, Prischi, F.
登録日2024-02-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
To Be Published
8QXB
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TDP-43 amyloid fibrils: Morphology-2
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QXA
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TDP-43 amyloid fibrils: Morphology-1b
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QX9
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BU of 8qx9 by Molmil
TDP-43 amyloid fibrils: Morphology-1a
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QO9
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BU of 8qo9 by Molmil
Cryo-EM structure of a human spliceosomal B complex protomer
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R.
登録日2023-09-28
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (5.29 Å)
主引用文献New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
8PX5
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BU of 8px5 by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe., solved at wavelength 2.75 A
分子名称: Rpb7-binding protein seb1
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Wittmann, S, Renner, M, Grimes, J.M, Wagner, A.
登録日2023-07-22
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8PVL
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BU of 8pvl by Molmil
Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.19 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PVK
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BU of 8pvk by Molmil
Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PV7
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BU of 8pv7 by Molmil
Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.12 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PV6
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BU of 8pv6 by Molmil
Chaetomium thermophilum pre-60S State 3 - post-5S rotation with Rix1 complex with Foot - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PV4
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BU of 8pv4 by Molmil
Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PV3
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BU of 8pv3 by Molmil
Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PV1
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BU of 8pv1 by Molmil
Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure
分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
登録日2023-07-17
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
登録日2023-07-07
公開日2023-10-18
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8PNT
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BU of 8pnt by Molmil
Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
著者Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
登録日2023-07-01
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
8PMP
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BU of 8pmp by Molmil
Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
著者Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
登録日2023-06-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
分子名称: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
著者Hipp, C, Sattler, M.
登録日2023-05-14
公開日2023-07-26
最終更新日2023-08-16
実験手法SOLUTION NMR
主引用文献FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
8OZ0
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BU of 8oz0 by Molmil
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V.
登録日2023-05-06
公開日2024-02-07
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-04-17に公開中

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