PDB: 372 件ウェブページステータス検索Chemie searchBIRD

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1CX4	CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA 著者 Diller, T.C, Xuong, N.H, Taylor, S.S. 登録日 1999-08-28 公開日 2001-03-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure, 9, 2001
4Z07	Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kim, J.J, Reger, A.S, Arold, S.T, Kim, C. 登録日 2015-03-25 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure, 24, 2016
1RGS	REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP DEPENDENT PROTEIN KINASE 著者 Su, Y, Dostmann, W.R.G, Herberg, F.W, Durick, K, Xuong, N.-H, Ten Eyck, L, Taylor, S.S, Varughese, K.I. 登録日 1995-06-21 公開日 1996-12-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science, 269, 1995
1U12	M. loti cyclic nucleotide binding domain mutant 分子名称: IODIDE ION, POTASSIUM ION, SULFATE ION, ... 著者 Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. 登録日 2004-07-14 公開日 2004-11-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel Cell(Cambridge,Mass.), 119, 2004
1VP6	M.loti ion channel cylic nucleotide binding domain 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel 著者 Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. 登録日 2004-10-14 公開日 2004-10-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell(Cambridge,Mass.), 119, 2004
4QX5	Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: Insights for PKG agonist design 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, IODIDE ION, cGMP-dependent protein kinase 1 著者 Huang, G.Y, Gerlits, O.O, Blakeley, M.P, Sankaran, B, Kovalevsky, A.Y, Kim, C. 登録日 2014-07-18 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.318 Å) 主引用文献 Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design. Biochemistry, 53, 2014
4QXK	Joint X-ray/neutron structure of PKGIbeta in complex with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-dependent protein kinase 1 著者 Kim, C, Gerlits, O, Kovalevsky, A, Huang, G.Y. 登録日 2014-07-21 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION 主引用文献 Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design. Biochemistry, 53, 2014
6SYG	Crystal structure of the Cyclic Nucleotide-Binding Homology Domain of the human KCNH2 channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Ben-Bassat, A, Giladi, M, Haitin, Y. 登録日 2019-09-27 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge. J.Gen.Physiol., 152, 2020
6BQ8	Joint X-ray/neutron structure of PKG II CNB-B domain in complex with 8-pCPT-cGMP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(~2~H_2_)amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2-hydroxy-7-(~2~H)hydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl](~2~H)-1,9-dihydro-6H-purin-6-one, STRONTIUM ION, ... 著者 Kim, C, Kovalevsky, A, Gerlits, O. 登録日 2017-11-27 公開日 2018-03-21 最終更新日 2024-04-03 実験手法 NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION 主引用文献 Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator. Biochemistry, 57, 2018
6CPB	Crystal structure of the heme domain of CooA from Carboxydothermus hydrogenoformans 分子名称: Carbon monoxide oxidation system transcription regulator CooA-1, GLYCEROL, SULFATE ION 著者 Tripathi, S.M, Poulos, T.L. 登録日 2018-03-13 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.155 Å) 主引用文献 Testing the N-Terminal Velcro Model of CooA Carbon Monoxide Activation. Biochemistry, 57, 2018
2K0G	Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein 著者 Schunke, S, Stoldt, M, Willbold, D. 登録日 2008-02-02 公開日 2009-02-10 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP. Embo Rep., 10, 2009
6HQ2	Structure of EAL Enzyme Bd1971 - apo form 分子名称: EAL Enzyme Bd1971 著者 Lovering, A.L, Cadby, I.T. 登録日 2018-09-24 公開日 2019-07-31 最終更新日 2019-09-11 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase. Embo J., 38, 2019
6HYI	Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine 分子名称: INOSINE, Protein kinase A regulatory subunit 著者 Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. 登録日 2018-10-22 公開日 2019-11-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.39944851 Å) 主引用文献 Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
6HYQ	Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi bound to guanosine 分子名称: ACETATE ION, GUANOSINE, Protein kinase A regulatory subunit 著者 Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. 登録日 2018-10-22 公開日 2019-11-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi in complex with guanosine to be published
2D93	Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 分子名称: Rap guanine nucleotide exchange factor 6 著者 Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-12-08 公開日 2006-06-08 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 to be published
7MBJ	Crystal structure of cGMP dependent protein kinase I alpha (PKG I alpha)CNB-A domain with R177Q mutation 分子名称: cGMP-dependent protein kinase 1 著者 Kim, J.J, Casteel, D.E, Kim, C. 登録日 2021-03-31 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
6NP6	Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis 分子名称: Crp/Fnr family transcriptional regulator, GLYCEROL 著者 Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Scarsdale, J.N, Lewis, J.P. 登録日 2019-01-17 公開日 2019-06-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Nitrosative Stress Sensing in Porphyromonas gingivalis: Structure and Mechanisms of the Heme Binding Transcriptional Regulator HcpR. Acta Crystallogr D Struct Biol, 75, 2019
2KXL	Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state 分子名称: Cyclic nucleotide-gated potassium channel mll3241 著者 Schunke, S, Stoldt, M, Willbold, D. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc.Natl.Acad.Sci.USA, 108, 2011
5T3N	Sp-2Cl-cAMPS bound to PKAR CBD2 分子名称: (2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one, IODIDE ION, cAMP-dependent protein kinase regulatory subunit 著者 Littler, D.R, Gilson, P. 登録日 2016-08-26 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
2MHF	Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel 分子名称: Uncharacterized protein 著者 Li, Q, Ng, H. 登録日 2013-11-21 公開日 2014-04-02 最終更新日 2022-08-24 実験手法 SOLUTION NMR 主引用文献 Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel. J.Struct.Biol., 186, 2014
2MNG	Apo Structure of human HCN4 CNBD solved by NMR 分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Akimoto, M, Zhang, Z, Boulton, S, Selvaratnam, R, VanSchouwen, B, Gloyd, M, Accili, E.A, Lange, O.F, Melacini, G. 登録日 2014-04-03 公開日 2014-06-04 最終更新日 2015-02-11 実験手法 SOLUTION NMR 主引用文献 A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J.Biol.Chem., 289, 2014
5V30	Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis 分子名称: GLYCEROL, SULFATE ION, Transcriptional regulator 著者 Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Lewis, J.P. 登録日 2017-03-06 公開日 2018-06-13 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Nitrosative stress sensing in Porphyromonas gingivalis: structure of and heme binding by the transcriptional regulator HcpR. Acta Crystallogr D Struct Biol, 75, 2019
2N7G	Structure of the cyclic nucleotide-binding homology domain of the hERG channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Li, Y, Ng, H, Li, Q, Kang, C. 登録日 2015-09-10 公開日 2016-05-18 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome Sci Rep, 6, 2016
2MPF	Solution structure human HCN2 CNBD in the cAMP-unbound state 分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Saponaro, A, Pauleta, S.R, Cantini, F, Matzapetakis, M, Hammann, C, Banci, L, Thiel, G, Santoro, B, Moroni, A. 登録日 2014-05-16 公開日 2014-09-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc.Natl.Acad.Sci.USA, 111, 2014
2PTM	Structure and rearrangements in the carboxy-terminal region of SpIH channels 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT HEXAMMINE(III), Hyperpolarization-activated (Ih) channel 著者 Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N. 登録日 2007-05-08 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure and rearrangements in the carboxy-terminal region of SpIH channels. Structure, 15, 2007

 

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