PDB: 106 件ウェブページステータス検索Chemie searchBIRD

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5EX9	Structure of P450 StaF from glycopeptide antibiotic A47934 biosynthesis; glycerol cryo 分子名称: Cytochrome P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Cryle, M.J, Ulrich, V. 登録日 2015-11-23 公開日 2017-01-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934. Beilstein J Org Chem, 12, 2016
5EX8	Structure of P450 StaF from glycopeptide antibiotic A47934 biosynthesis; ethylene glycol cryo 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Cryle, M.J, Ulrich, V. 登録日 2015-11-23 公開日 2017-01-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934. Beilstein J Org Chem, 12, 2016
5HH3	OxyA from Actinoplanes teichomyceticus 分子名称: ACETATE ION, GLYCEROL, OxyA protein, ... 著者 Haslinger, K, Cryle, M.J. 登録日 2016-01-09 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of OxyAtei : completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade. Febs Lett., 590, 2016
1GAC	NMR structure of asymmetric homodimer of a82846b, a glycopeptide antibiotic, complexed with its cell wall pentapeptide fragment 分子名称: CELL WALL PENTAPEPTIDE, CHLOROORIENTICIN A, vancosamine, ... 著者 Kline, A.D, Prowse, W.G, Skelton, M.A, Loncharich, R.J. 登録日 1995-05-24 公開日 1996-08-17 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Conformation of A82846B, a Glycopeptide Antibiotic, Complexed with its Cell Wall Fragment: An Asymmetric Homodimer Determined Using NMR Spectroscopy. Biochemistry, 34, 1995
4EEC	Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934. 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, StaL, desulfo-A47934 著者 Shi, R, Cygler, M. 登録日 2012-03-28 公開日 2012-07-04 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of sulfonation of the glycopeptide antibiotic scaffold by the sulfotransferase StaL Proc.Natl.Acad.Sci.USA, 2012
3G2Q	Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with sinefungin 分子名称: PCZA361.24, SINEFUNGIN 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-01-31 公開日 2009-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chem.Biol., 16, 2009
3G2P	Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH) 分子名称: PCZA361.24, S-ADENOSYL-L-HOMOCYSTEINE 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-01-31 公開日 2009-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chem.Biol., 16, 2009
3G2M	Crystal Structure of the Glycopeptide N-methyltransferase MtfA 分子名称: PCZA361.24 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-01-31 公開日 2009-05-05 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chem.Biol., 16, 2009
3G2O	Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-methionine (SAM) 分子名称: PCZA361.24, S-ADENOSYLMETHIONINE 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-01-31 公開日 2009-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chem.Biol., 16, 2009
6M7L	Complex of OxyA with the X-domain from GPA biosynthesis 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase, Putative non-ribosomal peptide synthetase 著者 Greule, A, Izore, T, Tailhades, J, Peschke, M, Schoppet, M, Ahmed, I, Kulik, A, Adamek, M, Ziemert, N, De Voss, J, Stegmann, E, Cryle, M.J. 登録日 2018-08-20 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.648297 Å) 主引用文献 Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nat Commun, 10, 2019
6FSH	Crystal structure of hybrid P450 OxyBtei(BC/FGvan) 分子名称: ACETATE ION, OxyB protein, POTASSIUM ION, ... 著者 Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J. 登録日 2018-02-19 公開日 2018-05-23 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. J. Inorg. Biochem., 185, 2018
2OVB	Crystal Structure of StaL-sulfate complex 分子名称: SULFATE ION, StaL 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2007-02-13 公開日 2007-02-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. J.Biol.Chem., 282, 2007
2OV8	Crystal Structure of StaL 分子名称: StaL 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2007-02-13 公開日 2007-02-27 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. J.Biol.Chem., 282, 2007
2OVF	Crystal Structure of StaL-PAP complex 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, StaL 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2007-02-13 公開日 2007-02-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. J.Biol.Chem., 282, 2007
5EX6	Structure of P450 StaH from glycopeptide antibiotic A47934 biosynthesis 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, GLYCEROL, ... 著者 Cryle, M.J, Ulrich, V. 登録日 2015-11-23 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH. Mol Biosyst, 12, 2016
8GLC	A1 AncAla: Adenylation domain 1 core construct from ancestral reconstruction of glycopeptide antibiotic biosynthesis, alanine selection pocket 分子名称: MbtH-like short polypeptide, Non-ribosomal peptide synthetase 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-21 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
3RUN	New strategy to analyze structures of glycopeptide antibiotic-target complexes 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Economou, N.J, Townsend, T.M, Loll, P.J. 登録日 2011-05-05 公開日 2012-06-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A carrier protein strategy yields the structure of dalbavancin. J.Am.Chem.Soc., 134, 2012
3RUM	New strategy to analyze structures of glycopeptide antibiotic-target complexes 分子名称: 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranose, ISOPROPYL ALCOHOL, Maltose-binding periplasmic protein, ... 著者 Economou, N.J, Weeks, S.D, Grasty, K.C, Nahoum, V, Loll, P.J. 登録日 2011-05-05 公開日 2012-06-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 A carrier protein strategy yields the structure of dalbavancin. J.Am.Chem.Soc., 134, 2012
1GO6	Balhimycin in complex with Lys-D-ala-D-ala 分子名称: (2R,4S,6S)-4-azanyl-4,6-dimethyl-oxane-2,5,5-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... 著者 Lehmann, C, Bunkoczi, G, Vertesy, L, Sheldrick, G.M. 登録日 2001-10-19 公開日 2002-06-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Structures of Glycopeptide Antibiotics with Peptides that Model Bacterial Cell-Wall Precursors J.Mol.Biol., 318, 2002
1HHZ	Deglucobalhimycin in complex with cell wall pentapeptide 分子名称: (2R,4S,6S)-4-azanyl-4,6-dimethyl-oxane-2,5,5-triol, CELL WALL PEPTIDE, DEGLUCOBALHIMYCIN, ... 著者 Lehmann, C, Bunkoczi, G, Sheldrick, G.M, Vertesy, L. 登録日 2000-12-29 公開日 2003-09-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 Structures of Glycopeptide Antibiotics with Peptides that Model Bacterial Cell-Wall Precursors J.Mol.Biol., 318, 2002
1HHU	Balhimycin in complex with D-Ala-D-Ala 分子名称: (2R,4S,6S)-4-azanyl-4,6-dimethyl-oxane-2,5,5-triol, (4S)-2-METHYL-2,4-PENTANEDIOL, BALHIMYCIN, ... 著者 Lehmann, C, Bunkoczi, G, Sheldrick, G.M, Vertessy, L. 登録日 2000-12-28 公開日 2003-09-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (0.89 Å) 主引用文献 Structures of Glycopeptide Antibiotics with Peptides that Model Bacterial Cell-Wall Precursors J.Mol.Biol., 318, 2002
1HHY	Deglucobalhimycin in complex with D-Ala-D-Ala 分子名称: (2R,4S,6S)-4-azanyl-4,6-dimethyl-oxane-2,5,5-triol, D-ALANINE, DEGLUCOBALHIMYCIN, ... 著者 Lehmann, C, Bunkoczi, G, Sheldrick, G.M, Vertesy, L. 登録日 2000-12-29 公開日 2003-09-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (0.89 Å) 主引用文献 Structures of Glycopeptide Antibiotics with Peptides that Model Bacterial Cell-Wall Precursors J.Mol.Biol., 318, 2002
4MFP	The crystal structure of acyltransferase in complex with decanoyl-CoA and Tei pseudoaglycone 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, COENZYME A, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFL	The crystal structure of acyltransferase in complex with decanoyl-CoA and Tei pseudoaglycone 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein tcp24, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFQ	The crystal structure of acyltransferase in complex with CoA and 10C-Teicoplanin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, COENZYME A, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014

 

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