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2UVK
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BU of 2uvk by Molmil
Structure of YjhT
Descriptor: YJHT
Authors:Muller, A, Severi, E, Wilson, K.S, Thomas, G.H.
Deposit date:2007-03-12
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Sialic Acid Mutarotation is Catalyzed by the Escherichia Coli Beta-Propeller Protein Yjht.
J.Biol.Chem., 283, 2008
8PIF
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BU of 8pif by Molmil
Fragment 12 in complex with KLHDC2
Descriptor: 1,2-ETHANEDIOL, 2-(furan-3-yl)ethanoic acid, Kelch domain-containing protein 2
Authors:Boettcher, J, Mayer, M.
Deposit date:2023-06-21
Release date:2023-07-12
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:KLHDC2 - The Next Level
To Be Published
8SGF
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BU of 8sgf by Molmil
KLHDC2 Kelch Domain with KLHDC2 c-terminal peptide bound
Descriptor: GLYCEROL, HIS-SER-VAL-ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2
Authors:Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K.
Deposit date:2023-04-12
Release date:2024-01-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.418 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8SGE
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BU of 8sge by Molmil
KLHDC2 Kelch Domain with ligand KDRLKZ-1
Descriptor: GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid
Authors:Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K.
Deposit date:2023-04-12
Release date:2024-01-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.509 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8EBL
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BU of 8ebl by Molmil
Structure of KLHDC2 substrate binding domain bound to C-degron from EPHB2
Descriptor: GLU-ASP-SER-HIS-LYS-GLU-SER-ASN-ASP-CYS-SER-CYS-GLY-GLY, Kelch domain-containing protein 2
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2022-08-31
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
8EBM
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BU of 8ebm by Molmil
Structure of KLHDC2 substrate binding domain bound to KLHDC2's C-degron mimic
Descriptor: ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2022-08-31
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
6DO4
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BU of 6do4 by Molmil
KLHDC2 ubiquitin ligase in complex with SelS C-end degron
Descriptor: Kelch domain-containing protein 2, SELS C-END DEGRON
Authors:Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N.
Deposit date:2018-06-08
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
6DO3
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BU of 6do3 by Molmil
KLHDC2 ubiquitin ligase in complex with SelK C-end degron
Descriptor: Kelch domain-containing protein 2, SelK C-end Degron
Authors:Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N.
Deposit date:2018-06-08
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
6DO5
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BU of 6do5 by Molmil
KLHDC2 ubiquitin ligase in complex with USP1 C-end degron
Descriptor: Kelch domain-containing protein 2, USP1 C-END DEGRON
Authors:Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N.
Deposit date:2018-06-08
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
6ZYW
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BU of 6zyw by Molmil
Outer Dynein Arm-Shulin complex - overall structure (Tetrahymena thermophila)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Mali, G.R, Abid Ali, F, Lau, C.K, Carter, A.P.
Deposit date:2020-08-03
Release date:2021-01-20
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (8.78 Å)
Cite:Shulin packages axonemal outer dynein arms for ciliary targeting.
Science, 371, 2021
8GLV
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BU of 8glv by Molmil
96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella
Descriptor: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ...
Authors:Walton, T, Brown, A.
Deposit date:2023-03-23
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
8BWY
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BU of 8bwy by Molmil
In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ...
Authors:Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
Deposit date:2022-12-07
Release date:2023-05-10
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (38 Å)
Cite:ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
8BX8
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BU of 8bx8 by Molmil
In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
Deposit date:2022-12-08
Release date:2023-05-10
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (30.299999 Å)
Cite:ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
8SH2
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BU of 8sh2 by Molmil
KLHDC2 in complex with EloB and EloC
Descriptor: Elongin-B, Elongin-C, Kelch domain-containing protein 2
Authors:Digianantonio, K.M, Bekes, M.
Deposit date:2023-04-13
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8EBN
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BU of 8ebn by Molmil
Structure of KLHDC2-EloB/C tetrameric assembly
Descriptor: Elongin-B, Elongin-C, Kelch domain-containing protein 2
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2022-08-31
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
7KEK
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BU of 7kek by Molmil
Structure of the free outer-arm dynein in pre-parallel state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-10-11
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7KZM
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BU of 7kzm by Molmil
Outer dynein arm bound to doublet microtubules from C. reinhardtii
Descriptor: DC1, DC2, Dynein 11 kDa light chain, ...
Authors:Walton, T, Wu, H, Brown, A.B.
Deposit date:2020-12-10
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KZN
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BU of 7kzn by Molmil
Outer dynein arm core subcomplex from C. reinhardtii
Descriptor: DC1, DC2, Dynein 11 kDa light chain, ...
Authors:Walton, T, Wu, H, Brown, A.B.
Deposit date:2020-12-10
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7MOQ
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BU of 7moq by Molmil
The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ...
Authors:Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H.
Deposit date:2021-05-03
Release date:2021-07-14
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM.
Embo Rep., 22, 2021

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PDB entries from 2024-03-27

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